anti-Adiponectin (ADIPOQ) Antibodies

Human Adiponectin (ADIPOQ) interaction partners

1. preoperative adiponectin levels correlate with postoperative complications after cancer surgery

2. women with gestational diabetes showed significantly low adiponectin and high resistin (show RETN Antibodies) levels when compared with control group.

3. Late improvement of low-density lipoprotein cholesterol and adiponectin after transplant suggested that kidney transplant recipients may still have risk of cardiovascular events, especially in the first years.

4. Findings suggest a significant association between variants in COL13A1 (show COL13A1 Antibodies), ADIPOQ, SAMM50 (show SAMM50 Antibodies), and PNPLA3 (show PNPLA3 Antibodies), and risk of NAFLD (show TSC2 Antibodies)/elevated transaminase levels in Mexican adults with an admixed ancestry.

5. fetuin a to adiponectin ratio is more strongly associated with metabolic syndrome and its components than fetuin-A or adiponectin alone

6. Data suggest that first trimester measurement of adiponectin and 1,5-anhydroglucitol are potential early serum biomarkers for later onset of gestational diabetes; both serum levels are lower in women who later develop gestational diabetes than in women who do not. This study was conducted in Dublin, Ireland.

7. Worse nutritional state in de novo heart failure patients is associated with higher adiponectin plasma levels. Their levels were upregulated in adipose cells after being nutrients-starved. These results may help us to understand the adiponectin paradox in heart failure.

8. Adiponectin may be considered a biomarker of metabolic compensation, inversely associated with chronic low-grade inflammation. Circulating adiponectin is also associated with lower risk of adverse cardivascular events in patients with severe carotid stenosis.

9. Review/Meta-analysis: circulating adiponectin levels were significantly higher in patients with rheumatoid arthritis, but there was no correlation with disease activity.

10. ADIPOQ rs1501299 gene polymorphism is associated with an increased risk of new-onset diabetes mellitus after liver transplantation.

Mouse (Murine) Adiponectin (ADIPOQ) interaction partners

1. These data may indicate that insulin (show INS Antibodies) resistance in Adp(-/-) mice is likely caused by an increase in concentrations of TNFalpha (show TNF Antibodies) and FFA via downregulation of PPARalpha (show PPARA Antibodies).

2. Adiponectin improves metabolic health but has only minor effects on reproductive functions in the polycystic ovary syndromemouse model.

3. APN attenuates adverse cardiac remodeling following cardiac injury by up-regulating MMP-9 expression. APN up-regulates MMP-9 expression via activation of AMPK and ERK1/2.

4. the effects of APN (show ANPEP Antibodies) on the promotion of preadipocyte differentiation under inflammatory conditions may involve the PPARgamma (show PPARG Antibodies) signaling pathway, and at least partly depends on upregulation of PPARgamma (show PPARG Antibodies) expression.

5. Results demonstrate that adiponectin enhances inhibitory postsynaptic current onto neuropeptide Y (NPY (show NPY Antibodies)) neurons to attenuate action potential firing in NPY (show NPY Antibodies) neurons in a glucose-independent manner, being contrasted to its glucose-dependent effect on proopiomelanocortin (show POMC Antibodies) neurons.

6. Results show a reciprocal regulation of adiponectin and FGF19 (show FGF19 Antibodies) gene expression in mice.

7. Acrp30 (a globular form of adiponectin) reduces the expression of proinflammatory cytokines and the expression of RAGE (show AGER Antibodies) as beta amyloid transporters into brain. Moreover, Acrp30 attenuated the apoptosis and the tight junction disruption through AdipoR1 (show ADIPOR1 Antibodies)-mediated NF-kappaB (show NFKB1 Antibodies) pathway in beta amyloid-exposed bEnd.3 cells.

8. Findings demonstrate that adiponectin is an essential regulator of thermogenesis, and adiponectin is required for maintaining body temperature under cold exposure.

9. Chronic stress accelerates DPP4-mediated GLP-1 degradation and alters plasma adiponectin, accelerating vascular senescence and impairing ischemia-induced neovascularization.

10. AdipoQ antisense (AS) Long noncoding RNA (lncRNA) transfer from nucleus to cytoplasm inhibits adipogenesis through formation of an AdipoQ AS lncRNA/AdipoQ mRNA duplex to suppress the translation of AdipoQ mRNA.[

Pig (Porcine) Adiponectin (ADIPOQ) interaction partners

1. Adiponectin affects development of porcine uterine epithelia and reproductive performance through modulation of PI3K/AKT (show AKT1 Antibodies) and MAPK (show MAPK1 Antibodies) cell signaling pathway.

2. Results presented in this study indicate the modulatory effect of P4 on adiponectin system in the porcine uterus during early pregnancy, which may suggest the involvement of this adipokine in the early pregnancy establishment.

3. The fluctuations in adiponectin and orexin (show OX Antibodies) concentrations in the plasma and uterine lining fluid (ULF (show TRIP12 Antibodies)) suggest that the hormones present in ULF (show TRIP12 Antibodies) are mostly of local origin and that these hormones participate in the processes that accompany early pregnancy.

4. This study demonstrated the presence of adiponectin and its receptors in the uteri, conceptuses, and trophoblasts of pregnant pigs and that the local adiponectin system is dependent on the stage of pregnancy.

5. It was concluded that the recombinant ADPN (show PNPLA3 Antibodies) could express in eukaryotic expression vector pPICZaA-ADPN (show PNPLA3 Antibodies) constructed in this study.

6. study demonstrated that adiponectin and adiponectin receptors 1 and 2 messenger RNAs and proteins are present in the porcine hypothalamus and that their expression levels are determined by the pig's endocrine status related to the oestrous cycle

7. This study demonstrated the presence of adiponectin, AdipoR1 and AdipoR2 genes and proteins in the porcine uterus and the effect of the stage of the oestrous cycle on the expression of the adiponectin system.

8. inhibition of ADIPOQ gene changes the mRNA levels of the adipocyte differentiation transcription factors LPL (show LPL Antibodies), PPARgamma (show PPARG Antibodies) and AP2 (show TFAP2B Antibodies).

9. Myocardial ADN (show CFD Antibodies) was reduced in dilated cardiomyopathy in an AMPK (show PRKAA1 Antibodies)-independent manner.

10. Results indicated that PPARgamma is an essential regulatory factor for the transcriptional activity of ERp44, which in turn controls the secretion of adiponectin.

Cow (Bovine) Adiponectin (ADIPOQ) interaction partners

1. These data suggest that energy balance around parturition may regulate plasma adiponectin but do not support roles for lipid mobilization or sustained changes in the plasma concentration of leptin, insulin, growth hormone, or fatty acids.

2. Low level expression of adiponectin mRNA was found in all areas of bovine mammary gland tissues examined. AdipoR1 (show ADIPOR1 Antibodies) and AdipoR2 (show ADIPOR2 Antibodies) mRNAs were also detected in mammary tissues and their expression was particularly prominent in the parenchyma and cistern.

3. Data suggest that genetic variation in promoter region of ADIPOQ (SNPs g.81966235C>T, g.81966377T>C, and g.81966364D>I) contribute to adiposity/marbling in skeletal muscle/meat (and thus meat quality) of Hanwoo beef cattle of North Korea.

4. These data suggest differential contribution of adipose tissue depots to circulating adiponectin.

5. Association analysis indicated that variable duplication within the ADIPOQ gene is associated with body measurements.

6. 14 polymorphisms of the ADIPOQ gene were observed in Chinese cattle; 2 polymorphisms PR_-135 A>G and PR_-68 G>C were located in the core promoter region of ADIPOQ; 3 haplotypes in the 2 polymorphic sites were detected which produce effects on ADIPOQ transcription and are associated with growth traits

7. reduced plasma adiponectin belongs to the subset of hormonal adaptations in EL dairy cows facilitating mammary glucose uptake via promotion of insulin (show INS Antibodies) resistance

8. The physiologic status of the ovary has significant effects on the natural expression patterns of adiponectin and its receptors in follicular and luteal cells of bovine ovary.

9. The disulfide bonds help to maintain the mature octadecameric adiponectin structure and stabilize intermediates during the assembly.

10. Gobular adiponectin increased NO production in aortic endothlium by increasing NO synthase (show NOS Antibodies) activity.

Zebrafish Adiponectin (ADIPOQ) interaction partners

1. Adiponectin and adiponectin receptor genes are coexpressed during zebrafish embryogenesis and regulated by food deprivation

Rabbit Adiponectin (ADIPOQ) interaction partners

1. Data suggest that, in blastocysts developing under maternal diabetic conditions which includes hyperadiponectinemia, p38 MAPK (show MAPK14 Antibodies) is up-regulated compared to control; however, in blastocysts cultured in vitro with excess adiponectin, p38 MAPK (show MAPK14 Antibodies) is not up-regulated.

2. Adiponectin level partially reflects the severity of liver steatosis, but not the degree of liver inflammation.