anti-Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) Antibodies

ADH5 encodes a member of the alcohol dehydrogenase family. Additionally we are shipping Alcohol Dehydrogenase 5 (Class III), chi Polypeptide Proteins (30) and Alcohol Dehydrogenase 5 (Class III), chi Polypeptide Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ADH5 128 P11766
ADH5 100145871 P12711
ADH5 11532 P28474
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Top anti-Alcohol Dehydrogenase 5 (Class III), chi Polypeptide Antibodies at antibodies-online.com

Showing 10 out of 96 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Horse Rabbit Un-conjugated WB WB Suggested Anti-ADH5 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human kidney 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of ADH5 Antibody (Center) (ABIN652502) in K562 cell line lysates (35 µg/lane). ADH5 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma with ADH5 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Goat Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 12 to 15 Days
$455.40
Details
Human Rabbit Un-conjugated WB   100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IC, IF, WB Immunofluorescent analysis of ADH5 staining in HepG2 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody Western blot analysis of ADH5 expression in U251 (A), U937 (B) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of ADH5 Antibody (Center) in K562 cell line lysates (35ug/lane). ADH5 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, IHC, WB Immunofluorescence analysis of HepG2 cell using ADH5 antibody. Blue: DAPI for nuclear staining. 100 μL Log in to see 16 Days
$334.02
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Goat Un-conjugated ELISA, WB Western Blot: alcohol dehydrogenase 5 Antibody [ABIN1887411] - (0.5ug/ml) staining of Human Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$485.88
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western Blot at 1:4000 dilution Lane 1: K562 whole cell lysate Lane 2: SH-SY5Y whole cell lysate Lysates/proteins at 20 ug per lane. Western blot analysis of ADH5 using rabbit polyclonal ADH5 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ADH5 gene. 400 μL Log in to see 2 to 3 Days
$515.63
Details

ADH5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Alcohol Dehydrogenase 5 (Class III), chi Polypeptide Antibodies

  1. Human Polyclonal ADH5 Primary Antibody for ELISA, WB - ABIN188741 : Adinolfi, Adinolfi, Hopkinson: Immunological and biochemical characterization of the human alcohol dehydrogenase chi-ADH isozyme. in Annals of human genetics 1984 (PubMed)

More Antibodies against Alcohol Dehydrogenase 5 (Class III), chi Polypeptide Interaction Partners

Human Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) interaction partners

  1. GSNOR represents the prototype enzyme to disclose how denitrosylation plays a crucial role in tuning NO-bioactivity and how much it deeply impacts on cell homeostasis and human pathophysiology. (Review)

  2. It was concluded that in HepG2 cells, ADH5 is a source of formate for de novo purine biosynthesis, especially during folate deficiency when folate-dependent formate production is limited.

  3. Local structural differences between human class V ADH (show AVP Antibodies) and other human ADHs includes a for class V ADH (show AVP Antibodies) unique and conserved Lys51, a position directly involved in the catalytic mechanism in other ADHs, and nine other class V ADH (show AVP Antibodies)-specific residues.

  4. GSNOR expression has different effect on neuronal viability in dependence on the stimulus applied, and plays opposite roles in SH-SY5Y models of Parkinson's disease and amyotrophic lateral sclerosis

  5. ADH5 counteracts neuronal differentiation of neural stem cells and this effect can be reversed by pharmacological inhibition of ADH5.

  6. Results show that polymorphism of ADH6 (show ADH6 Antibodies) gene leads to heavy drinking in women.

  7. common ADH (show AVP Antibodies) variants conferred risk for both schizophrenia in African-Americans and autism in European-Americans.

  8. A decrease in ADH (show AVP Antibodies) IB, rather than GSNOR, correlates with human lung cancer.

  9. study compared individuals occupationally exposed to formaldehyde and controls to effects of XRCC3 (show XRCC3 Antibodies) Thr241Met, ADH5 Val309Ile and Asp353Glu polymorphisms; ADH5 polymorphisms did not show significant association with genotoxicity biomarkers

  10. Data suggest that GSNOR deficiency, through dysregulated S-nitrosylation, may promote hepatocellular carcinoma, possibly by inactivating a DNA repair system.

Mouse (Murine) Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) interaction partners

  1. Report inhibition of GSNOR activity by nebivolol leading to accumulation of nitrosothiols in cells, and this is associated with an enhanced vasodilation by S-nitrosoglutathione.

  2. Increased GSNOR expression during aging decreases S-nitrosation of CaMKIIalpha (show CAMK2 Antibodies) and reduces CaMKIIalpha (show CAMK2 Antibodies) synaptosomal accumulation.

  3. These data indicate a role for GSNOR in the host response to malaria infection and suggest that strategies to disrupt its activity will improve clinical outcomes.

  4. GSNOR may act as a "brake" on skeletal muscle contractile performance under physiological conditions by modulating nitrosylation/denitrosylation balance.

  5. Loss of GSNOR confers enhanced post-MI cardiac regenerative activity, characterized by enhanced turnover of cardiomyocytes and cardiac stem cells.

  6. Results show that ADH5 removes endogenous formaldehyde to prevent DNA adducts, and protects with FANCD2 (show FANCD2 Antibodies), hematopoietic stem cells, hepatocytes, and nephrons from endogenous DNA damage.

  7. S-nitrosoglutathione reductase-dependent modification of PPARgamma (show PPARG Antibodies) alters the balance between adipocyte and osteoblast differentiation and provides checkpoint regulation of the lineage bifurcation of these 2 lineages.

  8. These findings provide novel insights into the involvement of GSNOR and S-nitrosylation in neuromuscular atrophy and neuropathic pain that are associated with pathological states.

  9. Overexpression of ADH5 reduces both development and adult neuronal differentiation of neurons. This effect depends on the catalytic activity of ADH5 and involves ADH5-mediated denitrosation of histone deacetylase 2 (HDAC2 (show HDAC2 Antibodies)).

  10. GSNOR appears to play a crucial role in controlling pulmonary and systemic infection by K. pneumoniae.

Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) Antigen Profile

Protein Summary

This gene encodes class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This gene is expressed in the stomach as well as in the liver, and it contains a glucocorticoid response element upstream of its 5' UTR, which is a steroid hormone receptor binding site. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ADH5

  • alcohol dehydrogenase 5 (class III), chi polypeptide (ADH5) antibody
  • alcohol dehydrogenase 6 (class V) (ADH6) antibody
  • alcohol dehydrogenase 5 (adh5) antibody
  • alcohol dehydrogenase 5 (class III), chi polypeptide (Adh5) antibody
  • alcohol dehydrogenase 5 (class III), chi polypeptide L homeolog (adh5.L) antibody
  • adh-3 antibody
  • Adh-5 antibody
  • ADH1C antibody
  • adh3 antibody
  • ADH4 antibody
  • adh5 antibody
  • adhx antibody
  • FALDH antibody
  • fdh antibody
  • GSH-FDH antibody
  • gsnor antibody
  • wu:fb60b11 antibody

Protein level used designations for ADH5

S-(hydroxymethyl)glutathione dehydrogenase , alcohol dehydrogenase (class III), chi polypeptide , alcohol dehydrogenase class chi chain , alcohol dehydrogenase class-3 , alcohol dehydrogenase class-III , formaldehyde dehydrogenase , glutathione-dependent formaldehyde dehydrogenase , alcohol dehydrogenase 6 , aldehyde reductase , FALDH , FDH , GSH-FDH , alcohol dehydrogenase 1C (class I), gamma polypeptide , class III alcohol dehydrogenase , fb60b11 , ADH-B2 , alcohol dehydrogenase 2 , alcohol dehydrogenase B2 , class III alcohol dehydrogenase, chi subunit , S-nitrosoglutathione reductase , alcohol dehydrogenase 5 (class III), chi polypeptide L homeolog , alcohol dehydrogenase class 3 , alcohol dehydrogenase 4 (class II), pi polypeptide

GENE ID SPECIES
128 Homo sapiens
130 Homo sapiens
100009307 Oryctolagus cuniculus
116517 Danio rerio
100145871 Rattus norvegicus
11532 Mus musculus
505515 Bos taurus
100719427 Cavia porcellus
445841 Xenopus laevis
609781 Canis lupus familiaris
422705 Gallus gallus
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