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ALDH16A1 encodes a member of the aldehyde dehydrogenase superfamily. Additionally we are shipping ALDH16A1 Kits (13) and ALDH16A1 Proteins (4) and many more products for this protein.
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Human Polyclonal ALDH16A1 Primary Antibody for IF, WB - ABIN530568
Soderblom, Stadler, Jupille, Blackstone, Shupliakov, Hanna: Targeted disruption of the Mast syndrome gene SPG21 in mice impairs hind limb function and alters axon branching in cultured cortical neurons. in Neurogenetics 2010
Both the short and long forms of human ALDH16A1 protein would lack catalytic activity.
Data report that maspardin (show SPG21 Antibodies) localizes prominently to cytoplasm as well as to membranes, possibly at trans-Golgi network/late endosomal compartments, and that maspardin (show SPG21 Antibodies) interacts with the aldehyde dehydrogenase ALDH16A1.
ALDH16A1 is expressed in proximal and distal convoluted tubule cells in the cortex of the kidney and in zone 3 hepatocytes. RNA-seq and gene ontology enrichment analyses showed that cellular lipid and lipid metabolic processes are up-regulated.
This gene encodes a member of the aldehyde dehydrogenase superfamily. The family members act on aldehyde substrates and use nicotinamide adenine dinucleotide phosphate (NADP) as a cofactor. This gene is conserved in chimpanzee, dog, cow, mouse, rat, and zebrafish. The protein encoded by this gene interacts with maspardin, a protein that when truncated is responsible for Mast syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
aldehyde dehydrogenase 16 family, member A1
, aldehyde dehydrogenase family 16 member A1
, aldehyde dehydrogenase 16A1