anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) Antibodies

Protein Summary

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with ALDH2

• aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 1 (aldh2.1) antibody
• aldehyde dehydrogenase 2 family (mitochondrial) L homeolog (aldh2.L) antibody
• aldehyde dehydrogenase 2 family (mitochondrial) (aldh2) antibody
• aldehyde dehydrogenase 2 family (mitochondrial) (ALDH2) antibody
• aldehyde dehydrogenase 2 (aldh2) antibody
• Show all gene names
• aldehyde dehydrogenase (RHA1_RS43090) antibody
• aldehyde dehydrogenase (NAD(+)) (aldH2) antibody
• hypothetical protein (OE_RS03015) antibody
• aldehyde dehydrogenase (aldH2) antibody
• aldehyde dehydrogenase 2 family (mitochondrial) (Aldh2) antibody
• aldehyde dehydrogenase 2, mitochondrial (Aldh2) antibody

• Ahd-5 antibody
• Ahd5 antibody
• ALDH-E2 antibody
• aldh2 antibody
• aldh2a antibody
• Show all synonym aliases
• ALDHI antibody
• ALDM antibody
• MGC80785 antibody
• rf2b antibody
• zgc:63786 antibody

Protein level used designations for ALDH2

aldehyde dehydrogenase 2 , aldehyde dehydrogenase 2 family (mitochondrial) , aldehyde dehydrogenase 2 family (mitochondrial)a , aldehyde dehydrogenase 2.1 , mitochondrial aldehyde dehydrogenase 2 , ALDH2B6 , mitochondrial aldehyde dehydrogenase RF2B , aldehyde dehydrogenase , aldehyde dehydrogenase (NAD(+)) , ALDH class 2 , ALDH-E2 , aldehyde dehydrogenase, mitochondrial , aldehyde dehydrogenase, mitochondrial-like , acetaldehyde dehydrogenase 2 , liver mitochondrial ALDH , nucleus-encoded mitochondrial aldehyde dehydrogenase 2 , ALDH1 , aldehyde dehydrogenase 2, mitochondrial , mitochondrial aldehyde dehydrogenase , ALDHI , AHD-M1