anti-AlkB, Alkylation Repair Homolog 5 (E. Coli) (ALKBH5) Antibodies

Probable dioxygenase that requires molecular oxygen, alpha-ketoglutarate and iron (By similarity).. Additionally we are shipping ALKBH5 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ALKBH5 303193  
ALKBH5 54890 Q6P6C2
ALKBH5 268420 Q3TSG4
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Top anti-ALKBH5 Antibodies at antibodies-online.com

Showing 10 out of 34 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: ALKBH5 Antibody [NBP1-82188] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4 Western Blot: ALKBH5 Antibody [NBP1-82188] - analysis of ALKBH5 in MDA-MB-231 human breast cancer subclones using anti-ALKBH5 antibody. Image from verified customer review. 0.1 mL Log in to see 7 to 9 Days
$491.63
Details
Human Rabbit Un-conjugated WB ALKBH5 Antibody (Center)  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the ALKBH5 Antibody detected the ALKBH5 protein (arrow). Overlay histogram showing U-2 OS cells stained with ABIN2849896(green line). The cells were fixed with 2% paraformaldehyde (10 min) and then permeabilized with 90% methanol for 10 min. The cells were then icubated in 2% bovine serum albumin to block non-specific protein-protein interactions followed by the antibody (ABIN2849896, 1:25 dilution) for 60 min at 37ºC. The secondary antibody used was Goat-Anti-Rabbit IgG, DyLight® 488 Conjugated Highly Cross-Adsorbed(1583138) at 1/200 dilution for 40 min at 37ºC. Isotype control antibody (blue line) was rabbit IgG1 (1μg/1x10^6 cells) used under the same conditions. Acquisition of >10, 000 events was performed. Dilution: 1:25 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of ALKBH5 expression in 293 cell line lysate ,The lane on the left is treated with the antigen-specific peptide. 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using ALKBH5 antibody (ABIN5997228) at 1:3000 dilution. 100 μL Log in to see 11 to 18 Days
$412.19
Details
Human Mouse Un-conjugated WB Western Blot analysis of ALKBH5 expression in transfected 293T cell line by ALKBH5 MaxPab polyclonal antibody.<br><br>Lane 1: OFOXD transfected lysate(50.38 KDa).<br>Lane 2: Non-transfected lysate.<br> 50 μg Log in to see 11 to 12 Days
$440.00
Details
Human Mouse Un-conjugated WB   50 μg Log in to see 7 to 9 Days
$837.83
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 11 to 16 Days
$594.00
Details
Human Rabbit FITC ELISA, WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details
Human Rabbit HRP ELISA, WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details

Top referenced anti-ALKBH5 Antibodies

  1. Human Polyclonal ALKBH5 Primary Antibody for IHC, IHC (p) - ABIN4279674 : Zhang, Samanta, Lu, Bullen, Zhang, Chen, He, Semenza: Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m⁶A-demethylation of NANOG mRNA. in Proceedings of the National Academy of Sciences of the United States of America 2016 (PubMed)
    Show all 2 Pubmed References

More Antibodies against ALKBH5 Interaction Partners

Human AlkB, Alkylation Repair Homolog 5 (E. Coli) (ALKBH5) interaction partners

  1. Overexpression of ALKBH5 in MIA-PaCa-2 and BxPC-3 cells, demonstrats that ALKBH5 could inhibit cell migration and invasion and ALKBH5 inhibits cell motility by demethylating and increasing expression of KCNK15- AS1.

  2. N(6)-Methyladenosine itself serves as a 'conformational marker', which induces different conformational outcomes in RNAs depending on sequence context. This critically impacts its interactions with several m6A (show GPM6A Antibodies)-recognising proteins, including FTO (show FTO Antibodies) and ALKBH5.

  3. ALKBH5 knockdown in breast cancer cells significantly decreased metastasis from breast to lungs in immunodeficient mice

  4. ALKBH5-FOXM1 (show FOXM1 Antibodies) pathway is critical for glioblastoma proliferation and tumorigenesis.ALKBH5 expression increases in glioblastoma stem-like cells and predicts poor survival in glioblastoma patients.

  5. HIF-dependent ALKBH5 expression mediates enrichment of BCSCs in the hypoxic tumor microenvironment

  6. The ALKBH5 gene may play a role in conferring risk of MDD in the Chinese population.

  7. Structures of human ALKBH5 demethylase (show MBD2 Antibodies) reveal a unique binding mode for specific single-stranded N6-methyladenosine RNA demethylation.

  8. Modelling substrate into the active site of ALKBH5 reveals conserved residues important for recognition and demethylation mechanisms.

  9. findings provide a structural basis for understanding the substrate recognition specificity of Alkbh5 and offer a foundation for selective drug design against AlkB (show ALKBH Antibodies) members

  10. ALKBH5 is a RNA demethylase (show MBD2 Antibodies) and its action strongly suggests that the reversible methyladenosine modification has fundamental and broad functions in mammalian cells.

Mouse (Murine) AlkB, Alkylation Repair Homolog 5 (E. Coli) (ALKBH5) interaction partners

  1. This study identified reversible m6A (show GPM6A Antibodies) modification as a critical mechanism of posttranscriptional control of mRNA fate in late meiotic and haploid spermatogenic cells.

ALKBH5 Antigen Profile

Protein Summary

Probable dioxygenase that requires molecular oxygen, alpha-ketoglutarate and iron (By similarity).

Gene names and symbols associated with ALKBH5

  • alkB homolog 5, RNA demethylase (Alkbh5) antibody
  • alkB homolog 5, RNA demethylase L homeolog (alkbh5.L) antibody
  • alkB homolog 5, RNA demethylase (ALKBH5) antibody
  • Abh5 antibody
  • AW050020 antibody
  • AW215868 antibody
  • E130207K11 antibody
  • Ofoxd antibody
  • OFOXD1 antibody
  • RGD1309496 antibody

Protein level used designations for ALKBH5

RNA demethylase ALKBH5 , alkylated DNA repair protein alkB homolog 5 , alpha-ketoglutarate-dependent dioxygenase alkB homolog 5 , probable alpha-ketoglutarate-dependent dioxygenase ABH5 , oxoglutarate and iron-dependent oxygenase domain containing

GENE ID SPECIES
303193 Rattus norvegicus
444130 Xenopus laevis
54890 Homo sapiens
268420 Mus musculus
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