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Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium.
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Angiopoietin-like protein 1 expression is related to intermuscular connective tissue and cartilage development
We conclude that angptl1 may have a beneficial role in the preservation of vascular integrity following focal cerebral ischemia.
Low levels of ANGPTL1 is associated with colorectal cancer metastasis.
ANGPTL1 inhibited angiogenesis by interacting with integrin alpha1beta1 receptor to suppress the downstreamJAK2-STAT3 (show STAT3 Proteins) signaling pathway.
Aberrant expression of ANGPTL1 in cumulus cells is potentially associated with impaired oocyte developmental competence in polycystic ovary syndrome.
Retinoic acid receptor beta (show RARB Proteins) and angiopoietin-like protein 1 are involved in the regulation of human androgen biosynthesis
ANGPTL1 represses lung cancer cell motility by abrogating the expression of the epithelial mesenchymal transformation mediator SLUG.
Immunohistochemical staining of Ang-1 was observed in smooth muscle cells, whereas Ang-2 was detected in endothelial cells, smooth muscle cells and macrophages.
Overexpression of angiopoietin 1 (show ANGPT1 Proteins) and metalloproteinases may be the characteristic feature of endometrium with greater potential to transform into endometriotic lesions in the peritoneal cavity.
cardiac-specific and hypoxia-induced coexpression of VEGF (show VEGFA Proteins) and Ang1 (show ANGPT1 Proteins) improves the perfusion and function of porcine MI heart through the induction of angiogenesis and cardiomyocyte proliferation
Data show that angiopoietin-like proteins zangptl1 and 2 are required for definitive HSPCs formation, and genetically interact with notch (show NOTCH1 Proteins) receptor.
Over-expression of angpt1 (show ANGPT1 Proteins) or partial down-regulation of the endogenous Angpt1 (show ANGPT1 Proteins) antagonist angpt2 (show ANGPT2 Proteins) rescues hemorrhage. This is the first direct in vivo link between hedgehog (show SHH Proteins) signaling and the induction of vascular stability
developmental expression of Angptl1, 2 and 6 in zebrafish
Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. The protein encoded by this gene is another member of the angiopoietin family that is widely expressed in adult tissues with mRNA levels highest in highly vascularized tissues. This protein was found to be a secretory protein that does not act as an endothelial cell mitogen in vitro.
, angiopoietin-related protein 1
, angiopoietin-related protein 1-like
, angiopoietin-like protein 1
, angiopoietin 3
, angiopoietin Y1
, dJ595C2.2 (angiopoietin Y1)
, angiopoietin-like protein