anti-Ankyrin Repeat Domain 11 (ANKRD11) Antibodies

This locus encodes an ankryin repeat domain-containing protein.

list all antibodies Gene Name GeneID UniProt
ANKRD11 29123 Q6UB99
ANKRD11 77087  
ANKRD11 365023  
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Top anti-ANKRD11 Antibodies at antibodies-online.com

Showing 10 out of 31 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB Human kidney WB Suggested Anti-ANKRD11 Antibody Titration: 1.25ug/ml Positive Control: Human Placenta 100 μL 2 to 3 Days
$229.00
Details
Bat Rabbit Un-conjugated IHC, IHC (p), WB 100 μL 11 to 14 Days
$493.17
Details
Human Rabbit Un-conjugated IHC, WB ANKRD11 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Epithelial cells of renal tubule (arrows) in Human Kidney. Magnification is at 400X ANKRD11 antibody used at 1.25 ug/ml to detect target protein. 100 μg 9 to 11 Days
$369.29
Details
Dog Rabbit Un-conjugated IHC, ELISA, WB 100 μL 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000; TMB staining; Read the data in MicroplateReader by 450 Antigen: 0.2ug/100ul, Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000, Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000, TMB staining, Read the data in MicroplateReader by 450nm 100 μL 3 to 7 Days
$317.90
Details
Human Mouse Un-conjugated DB, WB   50 μg 11 to 14 Days
$493.17
Details
Human Rabbit Un-conjugated IHC (p), WB Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with ANKRD11 polyclonal antibody at 4-8 ug/mL working concentration. Western Blot analysis of human placenta tissue lysate with ANKRD11 polyclonal antibody at 1.25 ug/mL working concentration. 100 μL 11 to 12 Days
$356.00
Details
Human Rabbit Cy7 IF (p)   100 μL 14 to 21 Days
$416.90
Details
Human Rabbit Cy5 IF (p)   100 μL 14 to 21 Days
$416.90
Details
Human Rabbit Cy3 IF (p)   100 μL 14 to 21 Days
$416.90
Details

More Antibodies against ANKRD11 Interaction Partners

Human Ankyrin Repeat Domain 11 (ANKRD11) interaction partners

  1. ANKRD11 variants cause KBG syndrome and Coffin-Siris-like syndrome.

  2. ANKRD11 variants cause variable clinical features associated with KBG syndrome and Coffin-Siris-like syndrome.

  3. exome sequencing identified a novel de novo heterozygous single base pair duplication (c.6015dupA) in ANKRD11, which is predicted to lead to a premature stop codon and loss of function in ANKRD11, thereby implicating it as contributing to the molecular diagnosis of KBG syndrome.

  4. Here we report a large series of 39 patients with KBG syndrome; these patients harbored ANKRD11 mutations (20 cases) or deletions (19 cases). All the mutations were found by targeted molecular analysis on patients with clinical features suggestive of KBG.

  5. Twelve novel cases of haploinsufficiency for ANKRD11-flanking genes make the difference between KBG and 16q24.3 microdeletion syndromes.

  6. These findings point out the importance of screening ANKRD11 in young CdLS patients who were found to be negative for mutations in the five known CdLS genes.

  7. Further delineation of the KBG syndrome phenotype on large patients cohort caused by ANKRD11 aberrations has been presented.

  8. we conclude that severe short stature, intellectual disability, and macrodontia are the main characteristics in KBG syndrome related to ANKRD11 mutation

  9. ANKRD11 C-terminus plays an important role in regulating the abundance of the protein, and a disturbance of the protein abundance due to the mutations leads to KBG syndrome.

  10. AIB1, AIB1-delta4 and ANCO1 are important determinants of endocrine and growth factor responsiveness in breast cancer.

  11. The complete neurological and psychiatric features observed in two patients with KBG syndrome due to ANKRD11 mutations, are reported.

  12. Partial deletion of ANKRD11 results in the KBG phenotype distinct from the 16q24.3 microdeletion syndrome.

  13. aberrant DNA methylation of three CpGs in a 19 bp region within the ANKRD11 promoter may be responsible for its down-regulation in breast cancer.

  14. Mutations in ANKRD11 cause KBG syndrome and outline a fundamental role of ANKRD11 in craniofacial, dental, skeletal, and central nervous system development and function.

  15. ANKRD11 is a candidate gene for autism and variable cognitive impairment in the novel 16q24.3 microdeletion syndrome.

  16. Together, these results indicate that the transcriptional potential of ANCO-1 may be modulated by a combination of repression and activation signals.

  17. ANKRD11 has a role as a p53 coactivator and may be involved in a regulatory feedback loop with p53

Mouse (Murine) Ankyrin Repeat Domain 11 (ANKRD11) interaction partners

  1. Ankrd11 knockdown delayed radial migration of cortical neurons. ANKRD11-deficient neurons displayed markedly reduced dendrite growth and branching as well as abnormal dendritic spine morphology. Ankrd11 knockdown suppressed acetylation of epigenetic molecules such as p53 and Histone H3. Furthermore, the mRNA levels of Trkb, Bdnf, and neurite growth-related genes were downregulated in ANKRD11-deficient cortical neurons.

  2. ANKRD11 C-terminus plays an important role in regulating the abundance of the protein, and a disturbance of the protein abundance due to the mutations leads to KBG syndrome.

  3. A Glu->Lys missense mutation in a highly conserved region causes osteopenia and craniofacial abnormalities. Homozygosity causes embryo death. Ankrd11 is a genetic regular of bone homeostasis.

ANKRD11 Antigen Profile

Protein Summary

This locus encodes an ankryin repeat domain-containing protein. The encoded protein inhibits ligand-dependent activation of transcription. Mutations in this gene have been associated with KBG syndrome, which is characterized by macrodontia, distinctive craniofacial features, short stature, skeletal anomalies, global developmental delay, seizures and intellectual disability. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 2 and X.

Gene names and symbols associated with ANKRD11

  • ankyrin repeat domain 11 (ANKRD11) antibody
  • ankyrin repeat domain 11 (Ankrd11) antibody
  • ankyrin repeat domain 11 L homeolog (ankrd11.L) antibody
  • ankyrin repeat domain 11 (ankrd11) antibody
  • 2410104C19Rik antibody
  • 3010027A04Rik antibody
  • 6330578C09Rik antibody
  • 9530048I21Rik antibody
  • AA930108 antibody
  • ANCO-1 antibody
  • ANCO1 antibody
  • ANKRD11 antibody
  • Gm176 antibody
  • LZ16 antibody
  • T13 antibody
  • wu:fc59e05 antibody
  • wu:fi04c06 antibody
  • Yod antibody

Protein level used designations for ANKRD11

ankyrin repeat domain-containing protein 11 , ankyrin repeat-containing cofactor 1 , nasopharyngeal carcinoma susceptibility protein , ankyrin repeat domain 11 , ankyrin repeat domain-containing protein 11-like , fc59e05 , fi04c06

GENE ID SPECIES
29123 Homo sapiens
77087 Mus musculus
365023 Rattus norvegicus
415845 Gallus gallus
443986 Xenopus laevis
468078 Pan troglodytes
489658 Canis lupus familiaris
532856 Bos taurus
698722 Macaca mulatta
100050107 Equus caballus
100431329 Pongo abelii
100077260 Ornithorhynchus anatinus
100223787 Taeniopygia guttata
100485818 Xenopus (Silurana) tropicalis
100727156 Cavia porcellus
327352 Danio rerio
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