Ankyrin Repeat-Containing Protein (EHMT2) ELISA Kits

A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. Additionally we are shipping EHMT2 Antibodies (72) and EHMT2 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
EHMT2 10919 Q96KQ7
EHMT2 110147 Q9Z148
Anti-Rat EHMT2 EHMT2 361798  
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Top EHMT2 ELISA Kits at antibodies-online.com

Showing 2 out of 4 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human < 0.188 ng/mL 0.313 ng/mL - 20 ng/mL   96 Tests 11 to 18 Days
$838.60
Details
Mouse < 46.9 pg/mL 78 pg/mL - 5000 pg/mL   96 Tests 11 to 18 Days
$838.60
Details

More ELISA Kits for EHMT2 Interaction Partners

Human Ankyrin Repeat-Containing Protein (EHMT2) interaction partners

  1. Cyclin D1 is required for recruitment of G9a to target genes in chromatin.

  2. we reported that FOXO1 is methylated by G9a at K273 residue in vitro and in vivo. Methylation of FOXO1 by G9a increased interaction between FOXO1 and a specific E3 ligase, SKP2, and decreased FOXO1 protein stability.

  3. G9a and GLP directly bound to the alpha subunit of HIF-1 (HIF-1alpha) and catalyzed mono- and di-methylation of HIF-1alpha. The methylation suppressed HIF-1 transcriptional activity.

  4. EHMT2 expression and enzymatic activity levels were elevated in EGFR-tyrosine kinase inhibitor-resistant non-small cell lung cancer cells.

  5. Suggest that a novel and functionally interdependent interplay between EZH2 and G9a regulates histone methylation-mediated epigenetic repression of the antifibrotic CXCL10 gene in idiopathic pulmonary fibrosis.

  6. In summary, it was demonstrated here that the overexpression of GLP is associated with a worse prognosis in Chronic Lymphocytic Leukemia (CLL) and that the inhibition of GLP/G9a complex leads to CLL cell death. These results suggest a potential use for GLP/G9a as markers for disease progression, as well as a promising epigenetic target for CLL treatment and prevention of disease evolution.

  7. Results show that casein kinase 2 alpha (CK2 )downregulation leads to H3K9me3 and senescence-associated heterochromatic foci (SAHF) formation by increasing H3K9 trimethylase SUV39h1 (SUV39h1) and decreasing H3K9 dimethylase G9a (G9a).

  8. EHMT2 rs35875104 showed a strong association with the risk of chronic hepatitis B.

  9. Data found that EHMT2 expression was upregulated in breast cancer (BRC) tissues and cell lines, which indirectly controlled HSPD1 expression and its localization, thus inhibiting cell apoptosis. These results identified EHMT2 as a novel BRC prognostic marker.

  10. that G9a contributes to biliary tract cancer carcinogenesis and may represent a potential prognostic factor as well as a therapeutic target

  11. High G9A expression is associated with Ovarian Cancer metastasis.

  12. Our results demonstrate of the central role of G9a HMT in the promotion of endothelial cells proliferation, and suggest that endothelial G9a HMT may be a target in the treatment of vascular proliferative disorders and tumor neovascularization.

  13. unveil E4BP4 as a critical transcriptional modulator repressing RASSF8 expression through histone methyltransferases, G9a and SUV39H1.

  14. Results establish a direct functional link between G9a and MMP-9 in the context of pro-osteoclastogenic transcriptional programs. The model suggests that G9a mediated H3K27me1 serves as an essential mark for MMP-9 recruitment and proteolytic activity at genes encoding positive regulators of osteoclast differentiation, thus keeping them active.

  15. The study identified that decreased expression of SATB2 was correlated with tumor progression and poor prognosis in non-small cell lung cancer (NSCLC) patients. Furthermore, SATB2 suppressed lung cancer cell invasion and metastasis and regulated the expression of EMT-related proteins and histone methylation by G9a.

  16. G9a plays a role as an epigenetic mediator of hypoxic response in breast cancer

  17. Identified the tumor suppressor RARRES3 as a critical target of G9a. Epigenetic silencing of RARRES3 contributed to the tumor-promoting function of G9a

  18. regulatory pathway based on casein kinase 2-G9a-RPA permits homologous recombination in cancer cells

  19. these findings reveal a role for REST-associated G9a and histone H3K9 methylation in the repression of USP37 expression in medulloblastoma. Reactivation of USP37 by G9a inhibition has the potential for therapeutic applications in REST-expressing medulloblastomas

  20. Regulated methylation and phosphorylation serve as a switch controlling G9a and GLP coactivator function, suggesting that this mechanism may be a general paradigm for directing specific transcription factor and coregulator actions on different genes.

Arabidopsis thaliana Ankyrin Repeat-Containing Protein (EHMT2) interaction partners

  1. These results suggest that PIA2 modulates phyA-mediated PIF3 phosphorylation by physical interaction with PIF3 and that the secondary structure of the PIA2 N-terminus is important in this modulation.

  2. PIA2 interacts with and is phosphorylated by phytochrome A. PIA2 functions in the regulation of anthocyanin biosynthesis in Arabidopsis. [PIA2]

  3. ANK6 plays a central role in male-female gamete recognition, possibly by regulating mitochondrial gene expression.

Mouse (Murine) Ankyrin Repeat-Containing Protein (EHMT2) interaction partners

  1. The authors show that G9a accumulates typically at 4 to 8 cell stage to promote timely repression of a subset of 4 cell stage-specific genes. Loss of maternal inheritance of G9a disrupts the gene regulatory network resulting in developmental delay and destabilisation of inner cell mass lineages by the late blastocyst stage.

  2. G9a exerts oncogenic effects in colorectal cancer by increasing Plk1 expression. G9a dimethylated p53 at lysine 373, which in turn increased Plk1 expression and promoted CRC cell growth.

  3. Epidermis-specific deletion of G9a histone methyltransferase (G9a) results in higher chromatin accessibility without major morphological alterations.

  4. G9a facilitates maintenance of cellular identity of CD8 T cells.

  5. It has been shown in a genetic psoriasis model that N-WASP controls IL-23 expression in keratinocytes by regulating the degradation of the histone methyltransferases G9a and GLP, and H3K9 dimethylation of the IL-23 promoter.

  6. G9a has a novel role in modulating insulin signaling, at least in part, depending on its regulatory function on HMGA1

  7. G9a contributes to neuropathic pain development through epigenetic silencing of Kcna2 in the axotomized dorsal root ganglion.

  8. These results identify G9a-induced histone methylation at the OXT and AVP promoters in the Basolateral Amygdala as a mechanism for mediating stress-induced lasting behavioral depression and its reversal by exercise.

  9. The findings of this study suggested that G9a participates in the nerve injury-induced reduction of the Oprm1 gene likely through G9a-triggered blockage in the access of cyclic AMP response element binding protein to this gene.

  10. GLP/G9a H3K9 methyltransferase complex is an enzyme counteracting Jmjd1a-mediated H3K9 demethylation at the Sry locus in gonadal somatic cells

  11. G9a regulates cell proliferation and timing of differentiation and that G9a expression in the tooth mesenchyme is required for proper tooth development

  12. Jmjd2c and G9a are novel enhancer-associated factors. Loss of Jmjd2c abrogates G9a recruitment and further destabilises loading of the mediator and cohesin components Med1 and Smc1a at newly activated and poised enhancers in embryonic stem cell-derived epiblast-like cells.

  13. G9a is an important regulator in placental diseases caused by defective vascular maturation.

  14. miR-217-mediated, genetic, or pharmacological inactivation of EHMT1/2 was sufficient to promote pathological hypertrophy

  15. G9A overexpression is associated with peritoneal fibrosis.

  16. high levels of G9a-dependent H3K9me2 at ILC3-specific genetic loci, demonstrating that G9a-mediated repression of ILC3-associated genes is critical for the optimal development of ILC2s.

  17. G9a functions both as a co-activator and a co-repressor to enhance cellular proliferation and inhibit myogenic differentiation.

  18. GLP, but not G9a, inhibits proteasome subunit-encoding genes expression.

  19. These data reveal a marked difference in EHMT2 levels between mature brainstem and cortical areas and a decoupling between EHMT2 abundance and histone 3 lysine 9 methylations during brainstem differentiation.

  20. G9a-mediated histone methylation plays a critical role in Cd-induced male fertility damage and testicular cell apoptosis.

Pig (Porcine) Ankyrin Repeat-Containing Protein (EHMT2) interaction partners

  1. EHMT2 inhibitor BIX-01294 is a potent inhibitor of H3K9 dimethylation and transient alterations in global histone modifications can have profound effects on embryo developmental potential.

Cow (Bovine) Ankyrin Repeat-Containing Protein (EHMT2) interaction partners

  1. The data confirm the involvement of EHMT2 in the epigenetic regulation of IFN-b and demonstrate the activation of a general antiviral state after EHMT2 inhibition.

EHMT2 Antigen Profile

Antigen Summary

A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. This gene is found near this cluster\; it was mapped near the gene for C2 within a 120-kb region that included a HSP70 gene pair. These genes are all within the human major histocompatibility complex class III region. This gene was thought to be two different genes, NG36 and G9a, adjacent to each other but a recent publication shows that there is only a single gene. The protein encoded by this gene is thought to be involved in intracellular protein-protein interaction. There are three alternatively spliced transcript variants of this gene but only two are fully described.

Gene names and symbols associated with EHMT2

  • euchromatic histone lysine methyltransferase 2 (EHMT2) antibody
  • ankyrin repeat-containing protein (ank1) antibody
  • ankyrin repeat-containing protein (IscW_ISCW006888) antibody
  • ankyrin repeat-containing protein (Arnit_2917) antibody
  • Ankyrin repeat family protein (AT3G04470) antibody
  • Ankyrin repeat family protein (AT4G14390) antibody
  • Ankyrin repeat family protein (AT4G19150) antibody
  • Ankyrin repeat family protein (AT4G03500) antibody
  • Ankyrin repeat family protein (AT4G03450) antibody
  • Ankyrin repeat family protein (AT4G03460) antibody
  • Ankyrin repeat family protein (AT4G03440) antibody
  • Ankyrin repeat family protein (PIA1) antibody
  • Ankyrin repeat family protein (AT5G15500) antibody
  • Ankyrin repeat family protein (AT5G51160) antibody
  • Ankyrin repeat family protein (AT5G54620) antibody
  • Ankyrin repeat family protein (ANK6) antibody
  • Ankyrin repeat family protein (AT1G04780) antibody
  • Ankyrin repeat family protein (AT1G62050) antibody
  • euchromatic histone lysine N-methyltransferase 2 (Ehmt2) antibody
  • euchromatic histone lysine methyltransferase 2 (Ehmt2) antibody
  • Bat8 antibody
  • C6orf30 antibody
  • D17Ertd710e antibody
  • DL3235W antibody
  • F9H3.6 antibody
  • F9H3.7 antibody
  • F9H3.9 antibody
  • F9H3.13 antibody
  • F9H3_6 antibody
  • F9H3_7 antibody
  • F9H3_9 antibody
  • F9H3_13 antibody
  • F13G24.40 antibody
  • FCAALL.188 antibody
  • G9a antibody
  • GAT8 antibody
  • KMT1C antibody
  • MAF19.22 antibody
  • MAF19_22 antibody
  • MRB17.12 antibody
  • MRB17_12 antibody
  • MWD22.10 antibody
  • MWD22_10 antibody
  • Ng36 antibody
  • T18B16.120 antibody
  • T18B16_120 antibody
  • T20K14.110 antibody
  • T20K14_110 antibody
  • T27C4.12 antibody
  • T27C4_12 antibody

Protein level used designations for EHMT2

G9A histone methyltransferase , H3-K9-HMTase 3 , HLA-B associated transcript 8 , HLA-B-associated transcript 8 , ankyrin repeat-containing protein , histone H3-K9 methyltransferase 3 , histone-lysine N-methyltransferase EHMT2 , histone-lysine N-methyltransferase, H3 lysine-9 specific 3 , lysine N-methyltransferase 1C , protein G9a , euchromatic histone-lysine N-methyltransferase 2 , HLA-B associated transcript 8, rat orthologue

GENE ID SPECIES
10919 Homo sapiens
4606933 Azoarcus sp. BH72
8032296 Ixodes scapularis
9173113 Arcobacter nitrofigilis DSM 7299
819603 Arabidopsis thaliana
827084 Arabidopsis thaliana
827653 Arabidopsis thaliana
827731 Arabidopsis thaliana
827913 Arabidopsis thaliana
827916 Arabidopsis thaliana
827920 Arabidopsis thaliana
830677 Arabidopsis thaliana
831403 Arabidopsis thaliana
835190 Arabidopsis thaliana
835551 Arabidopsis thaliana
836244 Arabidopsis thaliana
839414 Arabidopsis thaliana
842501 Arabidopsis thaliana
110147 Mus musculus
361798 Rattus norvegicus
474851 Canis lupus familiaris
100124382 Sus scrofa
100355131 Oryctolagus cuniculus
100728628 Cavia porcellus
100059118 Equus caballus
514062 Bos taurus
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