anti-Apolipoprotein M (APOM) Antibodies

The protein encoded by APOM is an apolipoprotein and member of the lipocalin protein family. Additionally we are shipping Apolipoprotein M Kits (49) and Apolipoprotein M Proteins (27) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
APOM 55937 O95445
APOM 55938 Q9Z1R3
APOM 55939 P14630
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Top anti-Apolipoprotein M Antibodies at antibodies-online.com

Showing 10 out of 170 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, IHC ABIN190884 (5µg/ml) staining of paraffin embedded Human Liver. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 100 μg Log in to see 6 to 7 Days
$429.84
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (44 KDa) . Dilution: 1:500~1000 100 μg Log in to see 8 to 11 Days
$527.50
Details
Human Mouse Un-conjugated ELISA, ICC, WB Figure 1: Western blot analysis using ApoM mouse mAb against human serum (1, 2). Dilution: 1/500 - 1/2000 Figure 2: Immunofluorescence analysis of methanol-fixed L-02 (left) and Cos7 (right) cells using ApoM mouse mAb showing cytoplasmic and membrane localization. Dilution: 1/200 - 1/1000 100 μL Log in to see 10 to 11 Days
$577.50
Details
Human Goat Un-conjugated ELISA, IHC, WB ABIN570933 (0.5µg/ml) staining of Human Placenta lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN570933 (3.75µg/ml) staining of paraffin embedded Human Liver. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 100 μg Log in to see 6 to 7 Days
$429.84
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: THP-1 B: HL-60 12% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Human Serum; Primary Ab: 1µg/ml Rabbit Anti-Human APOM Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Log in to see 15 to 18 Days
$350.00
Details
Human Mouse Un-conjugated IHC, IHC (p), WB 100 μL Log in to see 11 to 14 Days
$522.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 16 Days
$366.77
Details
Human Goat Un-conjugated ELISA, IHC, IHC (p), WB Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-APOM / Apolipoprotein M antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml. 50 μg Log in to see 11 to 14 Days
$484.00
Details

Top referenced anti-Apolipoprotein M Antibodies

  1. Human Monoclonal Apolipoprotein M Primary Antibody for ICC, ELISA - ABIN1724661 : Duan, Dahlbäck, Villoutreix: Proposed lipocalin fold for apolipoprotein M based on bioinformatics and site-directed mutagenesis. in FEBS letters 2001 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal Apolipoprotein M Primary Antibody for ICC, ELISA - ABIN1724662 : Xu, Nilsson-Ehle, Ahrén: Correlation of apolipoprotein M with leptin and cholesterol in normal and obese subjects. in The Journal of nutritional biochemistry 2004 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal Apolipoprotein M Primary Antibody for IF, ELISA - ABIN965578 : Xu, Dahlbäck: A novel human apolipoprotein (apoM). in The Journal of biological chemistry 1999 (PubMed)
    Show all 3 Pubmed References

  4. Human Monoclonal Apolipoprotein M Primary Antibody for IF, ELISA - ABIN965579 : Zhang, Jiao, Hurtig, Dong, Zheng, Luo, Nilsson-Ehle, Ye, Xu: Expression pattern of apolipoprotein M during mouse and human embryogenesis. in Acta histochemica 2004 (PubMed)
    Show all 4 Pubmed References

  5. Human Monoclonal Apolipoprotein M Primary Antibody for ELISA, WB - ABIN565964 : Su, Jiao, Yang, Ye: Evaluation of apolipoprotein M as a biomarker of coronary artery disease. in Clinical biochemistry 2009 (PubMed)
    Show all 2 Pubmed References

  6. Human Monoclonal Apolipoprotein M Primary Antibody for RNAi, ELISA - ABIN565963 : Zhang, Zhu, Luo, Zheng, Nilsson-Ehle, Xu: Liver X receptor agonist downregulates hepatic apoM expression in vivo and in vitro. in Biochemical and biophysical research communications 2008 (PubMed)
    Show all 2 Pubmed References

  7. Human Polyclonal Apolipoprotein M Primary Antibody for IHC (p), IHC - ABIN188728 : Mosialou, Zannis, Kardassis: Regulation of human apolipoprotein m gene expression by orphan and ligand-dependent nuclear receptors. in The Journal of biological chemistry 2010 (PubMed)
    Show all 2 Pubmed References

  8. Mouse (Murine) Polyclonal Apolipoprotein M Primary Antibody for ELISA, WB - ABIN1573987 : Kurano, Tsukamoto, Hara, Ohkawa, Ikeda, Yatomi: LDL Receptor and ApoE are Involved in the Clearance of ApoM-associated Sphingosine 1-phosphate. in The Journal of biological chemistry 2014 (PubMed)

  9. Human Monoclonal Apolipoprotein M Primary Antibody for ELISA, WB - ABIN527810 : Bosteen, Dahlbäck, Nielsen, Christoffersen: Protein unfolding allows use of commercial antibodies in an apolipoprotein M sandwich ELISA. in Journal of lipid research 2015 (PubMed)

More Antibodies against Apolipoprotein M Interaction Partners

Human Apolipoprotein M (APOM) interaction partners

  1. apoM could be bound to high-density lipoprotein after secretion and then quickly exchanged with a non-lipoprotein-related compartment and to LDL to be slowly catabolized.

  2. Obese patients showed significantly lower plasmatic ApoM levels than people with normal body weight, and ApoM level showed a strong correlation with CRP, TNF-alpha, and IL-6 levels, which indicated that ApoM might be regulated by these inflammatory factors.

  3. These results demonstrated that ApoM protein mass were clearly higher in the NSCLC tissues than in non-small cell lung cancer (NSCLC) tissues. Overexpression of ApoM could promote NSCLC cell proliferation and invasion in vitro and tumor growth in vivo, which might be via upregulating S1PR1 and activating the ERK1/2 and PI3K/AKT signaling pathways.

  4. results do not suggest a diagnostic role for ApoM plasma levels in patients with primary VTE. Moreover, the current study suggests that role of ApoM as a risk factor may differ for primary VTE and recurrent VTE in male patients.

  5. These S1P-induced enhancements in growth factors and chemotactic cytokines in retinal pigment epithelium cells were significantly inhibited by ApoM treatment. Additionally, in vivo experiments using a laser-induced choroidal neovascularization (CNV) murine model demonstrated that intravitreal ApoM injection significantly reduced the progression of CNV formation.

  6. The potential of mean force for sphingosine-1-phosphate unbinding from apoM reflected a large binding strength of more than 60 kJ/mol. This high unbinding free energy for sphingosine-1-phosphate underlines the observed specificity of the physiological effects of sphingosine-1-phosphate as it suggests that the spontaneous release of sphingosine-1-phosphate from apoM is unlikely.

  7. results demonstrated that lower APOM levels in SLE patients and correlated with disease activity.

  8. Sequenced the ApoM gene in recurrent venous thromboembolism (VTE) and identified six polymorphisms. ApoM rs805297 was significantly associated with higher risk of VTE recurrence in male but not in female patients.

  9. Single nucleotide polymorphism in ApoM gene is associated with chronic obstructive pulmonary disease.

  10. ApoM T-855C and T-778C polymorphisms were found to be associated with obesity by regulating HDL metabolism, and the T alleles of apoM T-778C were shown to be more strongly correlated.

  11. liver mRNA levels of apoM and apoA1 decreased strongly upon sepsis induction.

  12. 17beta-estradiol induced up-regulation of apoM in HepG2 cells is through an ER-alpha-dependent pathway involving ER-alpha binding element in the promoter of the apoM gene.

  13. A shift in ApoM/sphingosine 1-phosphate between HDL-particles in women with type 1 diabetes mellitus Is associated with impaired anti-inflammatory effects of the ApoM/S1P complex.

  14. ApoM-bound sphingosine-1-phosphate regulates adhesion molecule abundance, leukocyte-endothelial adhesion, and endothelial barrier function via sphingosine-1-phosphate receptor1.

  15. HDL-associated ApoM is anti-apoptotic by delivering sphingosine 1-phosphate to S1P1 and S1P3 receptors on vascular endothelium.

  16. Plasma apoM concentrations are higher in patients with hyperlipidaemia than in healthy controls. Low plasma apoM levels in patients with T2DM are likely caused by diabetes but are not induced by hyperlipidaemia.

  17. The polymorphism C-724del in the promoter region of the apoM gene could confer the risk of T2DM among eastern Han Chinese. Unfortunately, the lowing of plasma apoM levels of C-724del mutant allele carriers compared with the wide-type homozygotes carriers in T2DM patients was not statistically different in present study, so further researchs were needed by enlarging the sample

  18. ApoM rs805296 polymorphism may be a risk factor for developing coronary artery disease [meta-analysis]

  19. ApoM/HDL-C and apoM/apoA1 ratios could be used as indicators for identification of DN from healthy people and from T2DM patients.

  20. ApoM may be a biomarker of coronary artery disease. ApoM-855 T-->C substitution provides binding sites for AP-2alpha and reduces ApoM transcription activity

Mouse (Murine) Apolipoprotein M (APOM) interaction partners

  1. Results suggested that SR-BI deficiency promoted ApoM expression, but the increased ApoM might be independent from high density lipoprotein-mediated cholesterol uptake in hepatocytes.

  2. apoM-S1P-S1PR1 signaling might underlie the pathogenesis of ALI and apoM could have physiological benefits to alleviate LPS-induced ALI.

  3. These S1P-induced enhancements in growth factors and chemotactic cytokines in retinal pigment epithelium cells were significantly inhibited by ApoM treatment. Additionally, in vivo experiments using a laser-induced choroidal neovascularization (CNV) murine model demonstrated that intravitreal ApoM injection significantly reduced the progression of CNV formation.

  4. This study highlights the complexity of Apom/S1P in atherosclerosis and challenges the notion that the Apom/S1P complex is anti-atherogenic, at least in Apoe-deficient mice.

  5. This suggests that the autophagy dysfunction caused by the deficiency of ApoM is an important factor in hepatic steatosis (triglyceride accumulation). ApoM plays a key role in normal autophagy activity in the liver and thereby further regulates the metabolism of liver lipids, particularly triglycerides.

  6. HDL facilitates S1P efflux from erythrocytes by both apoM-dependent and apoM-independent mechanisms. Moreover, apoM facilitates tubular reabsorption of S1P from the urine, however, with no impact on S1P plasma concentrations.

  7. The study suggests that vascular leakage of albumin-sized particles in ApoM deficiency is S1P- and S1P1-dependent and this dependency exacerbates the response to inflammatory stimuli.

  8. apoM might facilitate the maintenance of CD4(+) T-lymphocytes or could modify the T-lymphocytes subgroups in murine spleen

  9. Upon immune stimulation, Apom(-/-) mice developed more severe experimental autoimmune encephalomyelitis, characterized by increased lymphocytes in the central nervous system and breakdown of the blood-brain barrier

  10. LDL receptor and ApoE have roles in the clearance of ApoM-associated sphingosine 1-phosphate

  11. ApoM augmented insulin secretion by maintaining the S1P concentration under both in vivo and in vitro conditions.

  12. The present data indicate that the plasma apo-M levels modulate the ability of plasma to mobilize cellular cholesterol, whereas apo-M has no major effect on the excretion of cholesterol into feces.

  13. ApoM can bind oxidized phospholipids, increasing the antioxidant effect of HDL.

  14. Results show that apoM, by delivering S1P to the S1P(1) receptor on endothelial cells, is a vasculoprotective constituent of HDL.

  15. After refolding from inclusion bodies, the crystal structure of apoM (reported here at 2.5 A resolution) displays a novel yet unprecedented seven-stranded beta-barrel structure.

  16. apoM mainly associates with HDL in normal mice but also with the pathologically increased lipoprotein fraction in genetically modified mice; decreased apoM levels in apoA-I-deficient mice suggest a connection between apoM and apoA-I metabolism.

  17. ApoM transcripts were detectable in mouse embryos from day 7.5 to day 18.5

  18. in both liver and kidney, expression of apoM was significantly lower in leptin deficient ob/ob mice and in leptin-receptor deficient db/db mice than in control mice

  19. Overexpression of apoM in Ldlr(-/-) mice protected against atherosclerosis when the mice were challenged with a cholesterol-enriched diet.

  20. Megalin-mediated endocytosis in kidney proximal tubules prevents apoM excretion in the urine.

Apolipoprotein M (APOM) Antigen Profile

Protein Summary

The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene.

Gene names and symbols associated with anti-Apolipoprotein M (APOM) Antibodies

  • apolipoprotein M S homeolog (apom.S) antibody
  • apolipoprotein M (APOM) antibody
  • apolipoprotein M (apom) antibody
  • apolipoprotein M (Apom) antibody
  • 1190010O19Rik antibody
  • apo-M antibody
  • APOM antibody
  • fb62d12 antibody
  • G3a antibody
  • HSPC336 antibody
  • NG20 antibody
  • wu:fb62d12 antibody

Protein level used designations for anti-Apolipoprotein M (APOM) Antibodies

apolipoprotein M , NG20-like protein , alternative name: G3a, NG20 , protein G3a , apo-M , protein Px

GENE ID SPECIES
446928 Xenopus laevis
462561 Pan troglodytes
569714 Danio rerio
715848 Macaca mulatta
100037868 Xenopus (Silurana) tropicalis
55937 Homo sapiens
474843 Canis lupus familiaris
55938 Mus musculus
55939 Rattus norvegicus
100350574 Oryctolagus cuniculus
100733052 Cavia porcellus
692188 Sus scrofa
505830 Bos taurus
101121210 Ovis aries
100173132 Pongo abelii
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