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AQP3 encodes the water channel protein aquaporin 3. Additionally we are shipping AQP3 Kits (49) and AQP3 Proteins (4) and many more products for this protein.
Showing 10 out of 131 products:
Rat (Rattus) Polyclonal AQP3 Primary Antibody for ICC, IF - ABIN4281305
Gonen, Walz: The structure of aquaporins. in Quarterly reviews of biophysics 2006
Show all 4 Pubmed References
Human Polyclonal AQP3 Primary Antibody for IF (p), IHC (p) - ABIN673974
Zhang, Li, Liu, Guang, Yang, Mao, Zhu, Chen, Wang: The AQP-3 water channel and the ClC-3 chloride channel coordinate the hypotonicity-induced swelling volume in nasopharyngeal carcinoma cells. in The international journal of biochemistry & cell biology 2014
The mutated amino acid residues in the dominant alleles line the pore surface of Aqp3a and influence pore permeability.
Enhanced water and cryoprotectant permeability of porcine oocytes after artificial expression of human and zebrafish aquaporin-3 channels.
This study found that both the airway epithelial cells of AQP3-knockout mice and AQP3-knockdown HBECs exhibited an obviously impaired self-healing capacity with defective epithelial cell migration through AQP3-facilitated glycerol transport.
Decreased glycerol efflux from the skeletal muscles in AQP3 knockout mice may result in low exercise capacity.
treatment of human HepG2 cells with TCDD also increased the expression of AQP3 mRNA and protein
AQP3-facilitated H2O2 transport is required for NF-kappaB (show NFKB1 Antibodies) activation in keratinocytes in the development of psoriasis.
Studied the effect of the total tannins extract of rhubarb on expression od aquaporin 2 (show AQP2 Antibodies) and auqaporin 3 in diarrhoea mice.
AQP3 has a pro-differentiative role in epidermal keratinocytes and PLD2 (show PLD2 Antibodies) activity is necessary for this effect.
analysis of the molecular link between the circadian clock and AQP3 function in mouse dorsal skin and HaCaT cells
In a mouse model of intestinal ischemia the level of miR (show MLXIP Antibodies)-874 expression was inversely related to AQP3 protein expression.
We therefore suggest that AQP3-mediated H(2)O(2) uptake is required for chemokine (show CCL1 Antibodies)-dependent T cell migration in sufficient immune response.
It was concluded that acyl-CoA binding protein (show DBI Antibodies) via aquaporin 3 is necessary for intact urine concentrating ability through efflux over the basolateral membrane of the collecting duct.
provide evidence for the involvement of the JNK (show MAPK8 Antibodies) pathway in AQP3 regulation in isolated oligohydramnios tissues in vitro, in amniotic epithelial cells derived from normal amniotic fluid and fluid from patients with isolated oligohydramnios
The expression of AQP1 and 3 is a manifestation of physiological adaptation of functionally mature chondrocytes able to respond to the change of their internal environment influenced by extracellular matrix.
Results indicate that AQP3 promotes stem-like properties of gastric carcinoma (GC) cells by activating the Wnt (show WNT2 Antibodies)/GSK-3beta (show GSK3b Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling pathway.
The genetic variant rs426496 in AQP2 (show AQP2 Antibodies); rs591810 in AQP3 and rs1805127, rs1805128, and rs17173510, in KCNE1 (show KCNE1 Antibodies) were found in patients with Meniere's disease
The Adiponectin increases AQP3 expression through PPARalpha (show PPARA Antibodies)-mediated signaling inhepatic stellate cells.
skin dryness observed in intrinsic and extrinsic aged skin may be explained, at least in part, by AQP3 downregulation. This may open new avenues sufficient to control skin texture and beauty. Its interaction in skin protein organization and gene polymorphism can also be tackled in future research
Data show that the expression of aquaporin (AQP) 1 (show AQP1 Antibodies), AQP3, AQP5 (show AQP5 Antibodies), epithelial Na+ channel (ENaC (show SCNN1A Antibodies)) and sodium potassium ATPase (show DNAH8 Antibodies) (Na-K-ATPase (show ATP1A1 Antibodies)) are altered in patients with acute respiratory failure (ARF (show CDKN2A Antibodies)) due to diffuse alveolar damage (DAD), and the cause of DAD does not seem to influence the level of impairment of these channels.
epigenetic signatures at AQP3 and SOCS3 (show SOCS3 Antibodies) engage in low-grade inflammation across different tissues, possible via JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies) mediated pathways
RNA interference (RNAi) of aquaporin 3 (AQP3) retarded the growth and invasiveness of XWLC-05 lung cancer cells and decreased the activity of matrix metalloproteinase 2 (MMP2 (show MMP2 Antibodies)).
Taken together, our data, as a proof of principle, suggest that AQP3 can promote tumor growth of pancreatic cancer cells by activating the Mtor (show FRAP1 Antibodies) signaling pathway and provide a potential therapeutic target in the treatment of PDAC.
Data suggest that expression of AQP3 (aquaglyceroporin-3) in rumen mucosa can be modulated by dietary factors; here, AQP3 and UT-B (urea transporter B (show SLC14A1 Antibodies)) expression are upregulated with solid food intake (low-protein diet of plant forage) at weaning.
lack of AQP3 in bovine erythrocytes points to the lipid pathway as responsible for glycerol permeation and explains the low glycerol permeability and high E(a) for transport observed in ruminants.
AQP1 (show AQP1 Antibodies), AQP2 (show AQP2 Antibodies), and AQP3, and V2R (show AVPR2 Antibodies) expression increased with gestation age in the fetal kidney, suggesting that this induction might contribute to the maturation of urinary concentrating capacity
The full length coding sequences of porcine (Sus scrofa) AQP3, 7 and 9 and the genomic sequence of AQP3 including 6 exons and 5 introns, was cloned.
This gene encodes the water channel protein aquaporin 3. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein, also known as aquaporin 0. Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function, aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms.
, 31.4 kDa water channel protein
, aquaporin 3 (GIL blood group)