Aquaporin 8 Proteins (AQP8)

Aquaporin 8 (AQP8) is a water channel protein. Additionally we are shipping Aquaporin 8 Antibodies (56) and Aquaporin 8 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
AQP8 343 O94778
AQP8 29172 P56405
AQP8 11833 P56404
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Top Aquaporin 8 Proteins at

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg 50 to 55 Days
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg 50 to 55 Days
Escherichia coli (E. coli) Human Un-conjugated SDS-PAGE analysis of Human AQP8 Protein. 100 μg 11 to 18 Days
Wheat germ Human GST tag 10 μg 11 to 12 Days
Escherichia coli (E. coli) Cow Un-conjugated   5 applications 1 to 2 Days

AQP8 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
Rat (Rattus)
Mouse (Murine) ,

More Proteins for Aquaporin 8 (AQP8) Interaction Partners

Human Aquaporin 8 (AQP8) interaction partners

  1. Mitochondrial AQP8 is involved in SREBP2-controlled hepatocyte cholesterol biosynthesis.

  2. Structural basis for mutations in human AQP8 associated with colorectal cancer has been described.

  3. Aquaporin 8 expression is regulated by cholesterol in hepatic cells

  4. The control of AQP8-mediated H2O2 transport provides a novel mechanism to regulate cell signaling and survival during stress.

  5. In particular, AQP8 affected VEGF-induced redox signaling by increasing the sulfenation of the tumor suppressor PTEN, which resulted in its inactivation and, in turn, caused Akt activation.

  6. Aquaporins AQP3, -7, -8, and -11 proteins were found in sperm cells and localized in the head (AQP7), in the middle piece (AQP8) and in the tail (AQP3 and -11) in both the plasma membrane and in intracellular structures.

  7. No significant relationship was found between gallbladder mucosa aquaporin expression and the presence or absence of gallbladder stones.

  8. AQP6 and AQP8 had different expression degrees in epithelial ovarian tissues, which suggests that AQP6 and AQP8 may play certain roles in epithelial ovarian tumors.

  9. EGF induces AQP8 expression and cell migration in Eca-109 cells via the EGFR/Erk1/2 signal transduction pathway.

  10. increased AQP8, Erk1/2 and phosphorylated-Erk1/2 expression may play a role in transformation of cervical intraepithelila neoplasia into cervical cancer, and in early invasion and lymphatic metastasis of cervical cancer

  11. mtAQP8 knockdown induces necrotic cell death in human neoplastic hepatic cells, a finding that might be relevant to therapeutic strategies against hepatoma cells.

  12. AQP8 and its relationship with miRNAs may be involved in the pathogenesis of Ulcerative colitis (UC).

  13. AQP8 has a role in the pathogenesis of PCOS.

  14. the results here reported indicate that AQP8 is able to modulate H2O2 transport through the plasma membrane affecting redox signalling linked to leukaemia cell proliferation

  15. High Aquaporin 8 expression is associated with invasion of cervical cancer.

  16. The expression levels and immunoreactive score of AQP8 protein and mRNA increased in low-grade astrocytomas, and further increased in high-grade astrocytomas, especially in glioblastoma.

  17. AQP8 expression significantly increased in advanced stage of cervical cancer, deeper infiltration, metastatic lymph nodes and larger tumor volume.

  18. Reconstitution of water channel function and 2D-crystallization of human aquaporin 8.

  19. With the increase of cAMP, AQP8 mRNA and protein expressions significantly increased in WISH cells in vitro.

  20. The expression of AQP8 protein is positively correlated with bcl-2 protein in human cervical carcinoma.

Mouse (Murine) Aquaporin 8 (AQP8) interaction partners

  1. AQP8 silencing impairs H2O2 entry into I.29micro+ B lymphoma cells. AQP8 can act as an efficient H2O2 channel also in cells of the B lineage.

  2. Rotavirus diarrhea is associated with the downregulation of AQP1, -4, and -8 expression.

  3. AQP8 has a role in the formation of follicles and provided new insight into the molecular mechanisms of folliculogenesis.

  4. Data indicate selective expression of aquaporins 3 and 8 in primitive erythroblasts and aquaporins 1 and 9 in adult definitive erythroblasts.

  5. we conclude that AQP8 deficiency increases the number of mature follicles by reducing the apoptosis of granulosa cells, thus increasing the fertility of female mice[aquaporin 8]

  6. Studies confirmed the involvement of AQP8 in alpha-amylase 2 regulation.

  7. Phenotype of AQP8-null mice is not dramatically different from wild type mice.

  8. analysis of AQP8 and AQP1 water channel expression in the mouse gall-bladder epithelium

  9. The results support the conclusion that AQP8 can facilitate NH(3) transport but provide evidence against physiologically significant AQP8-facilitated NH(3) transport in mice.

  10. The Hg(2+)-sensitive AQP8, which was localized in elongated spermatids and spermatozoa, is a likely candidate for a water channel responsible for physiological sperm volume regulation crucial to in vivo fertilization.

Zebrafish Aquaporin 8 (AQP8) interaction partners

  1. these differential expression patterns of aqp8a.1, aqp8a.2, and aqp8b suggest that they possibly play distinct roles throughout the embryonic development by controlling or maintaining organ-specific cellular water homeostasis. Our study provides new evidence that organogenesis requires differential roles of Aqp8 proteins in zebrafish.

Aquaporin 8 (AQP8) Protein Profile

Protein Summary

Aquaporin 8 (AQP8) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 8 mRNA is found in pancreas and colon but not other tissues.

Gene names and symbols associated with Aquaporin 8 Proteins (AQP8)

  • aquaporin 8 (AQP8)
  • aquaporin 8 (Aqp8)
  • aquaporin 8a, tandem duplicate 1 (aqp8a.1)
  • hypothetical protein LOC734703 S homeolog (LOC734703.S)
  • aquaporin 8 (aqp8)
  • AI255744 protein
  • AQP-8 protein
  • AQP8 protein
  • aqp8a protein
  • db04c12 protein
  • mg:db04c12 protein
  • MGC116564 protein
  • zgc:103682 protein

Protein level used designations for Aquaporin 8 Proteins (AQP8)

aquaporin-8 , membrane water channel , aqp8aa , aquaporin 8 , aquaporin-8aa

343 Homo sapiens
29172 Rattus norvegicus
11833 Mus musculus
416566 Gallus gallus
443183 Ovis aries
447923 Danio rerio
450206 Bos taurus
468096 Pan troglodytes
608036 Canis lupus familiaris
734703 Xenopus laevis
100127152 Sus scrofa
100135726 Xenopus (Silurana) tropicalis
702167 Macaca mulatta
100008960 Oryctolagus cuniculus
100719922 Cavia porcellus
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