anti-ArfGAP with Coiled-Coil, Ankyrin Repeat and PH Domains 1 (ACAP1) Antibodies

GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface.. Additionally we are shipping ACAP1 Proteins (5) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ACAP1 9744 Q15027
ACAP1 216859 Q8K2H4
ACAP1 287443  
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Top anti-ACAP1 Antibodies at antibodies-online.com

Showing 10 out of 87 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Goat Un-conjugated ELISA, WB EB056122 staining (0.5µg/ml) of Jurkat lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg 6 to 7 Days
$429.84
Details
Human Rabbit Un-conjugated EIA, WB ACAP1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ACAP1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. ACAP1 Antibody (N-term) western blot analysis in mouse spleen tissue lysates (35 µg/lane).This demonstrates the ACAP1 antibody detected the ACAP1 protein (arrow). 0.4 mL 6 to 8 Days
$484.00
Details
Human Goat Un-conjugated EIA, IHC (p), WB 50 μg 6 to 8 Days
$495.00
Details
Cow Goat Un-conjugated ELISA, IHC, IHC (p), WB Human Tonsil (formalin-fixed, paraffin-embedded) stained with CENTB1 antibody ABIN337010 at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. Anti-ACAP1 / CENTB1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of Centaurin-β1 (Phospho-Ser554) using PMA treated NIH-3T3 whole cell lysates 100 μL 11 to 12 Days
$450.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts of Mouse lung tissue sample,using Centaurin 1 Antibody(ABIN6272787). 100 μL 11 to 12 Days
$390.77
Details
Cow Goat Un-conjugated WB   0.1 mg 4 to 8 Days
$462.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis in ZR-75-1 cell line lysates (35ug/lane). Western blot analysis in mouse spleen tissue lysates (35ug/lane). 400 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated WB 100 μg 11 to 14 Days
$507.83
Details
Human Rabbit Un-conjugated ELISA, IHC   100 μL Available
$363.46
Details

Top referenced anti-ACAP1 Antibodies

  1. Human Polyclonal ACAP1 Primary Antibody for ELISA, WB - ABIN547163 : Jackson, Brown, Nie, Miura, Foroni, Sun, Hsu, Donaldson, Randazzo: ACAPs are arf6 GTPase-activating proteins that function in the cell periphery. in The Journal of cell biology 2000 (PubMed)

More Antibodies against ACAP1 Interaction Partners

Human ArfGAP with Coiled-Coil, Ankyrin Repeat and PH Domains 1 (ACAP1) interaction partners

  1. The serum lever of Alzheimer's disease were decrease and the expression of ACAP1 strongly correlated with the Mini-Mental State Examination scores of the AD patients

  2. ACAP1 and ARAP2 each colocalize with Arf6 but they did not colocalize with each other and have opposing effects on focal adhesions.

  3. CENTB1 was up-regulated in patients with active UC as compared to UC remission and healthy control groups suggesting that it is involved in the inflammatory process.

  4. phosphorylation of ACAP1 relieves a localized mechanism of autoinhibition in regulating cargo binding

  5. the oncogenic potential of USP6 is linked to its ability to integrate cell migration and cytokinesis by regulating Arf6/ACAP1.

  6. ACAP1 promotes endocytic recycling by recognizing recycling sorting signals.

  7. CENTB1 selectively down-regulates NF-kappaB activation via NODs pathways, creating a "feedback" loop and suggesting a novel role of CENTB1 in innate immune responses to bacteria and inflammatory responses

  8. Results suggest that two ARF6 downstream molecules, PIP5K and ACAP1, function together in endosomal tubulation and that phosphoinositide levels may regulate endosomal dynamics.

  9. Results suggest that ACAP1, a GTPase-activating protein (GAP) for ADP-ribosylation factor (ARF) 6, is part of a novel clathrin coat complex that is regulated by ARF6 for endocytic recycling in two key physiological settings.

  10. ACAP1 has robust, constitutive Arf6 GAP activity in vivo, with little activity toward Arf1.

  11. Centaurin beta1/KIAA0050, is a member of the centaurin family of ADP-ribosylation factor directed GTPase-activating proteins. Binding of phosphoinositides to a pleckstrin homology domain may regulate subcellular localisation and activity.

  12. Centaurin beta1/KIAA0050, or ACAP1, is a phospholipid dependent, ARF6 preferring GTPase-activating protein. It can regulate cytoskeletal and membrane trafficking events in the cell periphery and may be regulated via a phosphoinositide-binding PH domain.

ACAP1 Antigen Profile

Protein Summary

GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface.

Gene names and symbols associated with ACAP1

  • ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 (ACAP1) antibody
  • ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 (Acap1) antibody
  • Centb1 antibody

Protein level used designations for ACAP1

centaurin beta1 , centaurin, beta 1 , ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 , arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1-like , arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 , centaurin-beta-1 , cnt-b1 , Arf GAP with coiled coil, ANK repeat and PH domains 1

GENE ID SPECIES
455275 Pan troglodytes
721824 Macaca mulatta
100016342 Monodelphis domestica
100072970 Equus caballus
100359236 Oryctolagus cuniculus
100481518 Ailuropoda melanoleuca
100607184 Nomascus leucogenys
100623422 Sus scrofa
508582 Bos taurus
9744 Homo sapiens
216859 Mus musculus
287443 Rattus norvegicus
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