ArfGAP with Dual PH Domains 1 Proteins (ADAP1)

binds inositol(1,3,4,5)tetrakisphosphate (InsP4) and phosphatidylinositol(3,4,5)trisphosphate (PtdInsP3)\;involved in inositol phosphate or inositol lipid signal transduction [RGD, Feb 2006].. Additionally we are shipping ADAP1 Antibodies (46) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ADAP1 11033 O75689
Mouse ADAP1 ADAP1 231821  
Rat ADAP1 ADAP1 171097  
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Top ADAP1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,960.83
Details
Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 15 to 18 Days
$749.00
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$860.20
Details

ADAP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,

More Proteins for ArfGAP with Dual PH Domains 1 (ADAP1) Interaction Partners

Human ArfGAP with Dual PH Domains 1 (ADAP1) interaction partners

  1. This review highlights the functions of the neuron-specific protein ADAP1 in neuronal differentiation and neurodegenerative diseases, with an overview of structural and biochemical properties of ADAP1. [review]

  2. SH-SY5Y cells, stably transfected with GFP-tagged-p42 (show EPB42 Proteins)(IP4), show an enhanced NRD (show PRDM1 Proteins) protein expression already at an earlier time point after retinoic acid stimulation.

  3. Tubulin (show TUBB Proteins) potentiates the interaction of the metalloendopeptidase (show THOP1 Proteins) nardilysin (show NRD1 Proteins) with the neuronal scaffold protein (show HOMER1 Proteins) p42IP4/centaurin-alpha1 (ADAP1).

  4. Full-length KIF13B and CENTA1 form heterotetramers that can bind four phosphoinositide molecules in the vesicle and transport it along the microtubule.

  5. The ARFGAP domain of p42IP4 is involved in the interaction and co-localization with RanBPM protein, without being the only interaction site.

  6. the up-regulated p42 (show EPB42 Proteins)(IP4) in Alzheimer's disease neurons may serve as a docking protein to recruit signaling molecules such as different subtypes of casein kinase I (show CSNK1D Proteins) to the plasma membrane.

  7. Results show that nucleolin interacts with centaurin-alpha(1) protein, suggesting that centaurin-alpha(1) may be part of a ribonucleoprotein complex.

  8. centaurin-alpha1 negatively regulates ARF6 (show ARF6 Proteins) activity by functioning as an in vivo PIP3-dependent ARF6 (show ARF6 Proteins) GAP

  9. p42IP4 receptor is expressed and distributed throughout the cell in HEK (show EPHA3 Proteins) cell lines and is located on chromosome 7, position 7p22.3.

  10. Authors propose alternative concepts of how elevated levels of p42IP4 might relate to its interaction with nucleolin (show NCL Proteins) in the pathomechanisms of Alzheimer's disease.

ADAP1 Protein Profile

Protein Summary

binds inositol(1,3,4,5)tetrakisphosphate (InsP4) and phosphatidylinositol(3,4,5)trisphosphate (PtdInsP3)\;involved in inositol phosphate or inositol lipid signal transduction

Gene names and symbols associated with ADAP1

  • ArfGAP with dual PH domains 1 (ADAP1)
  • ArfGAP with dual PH domains 1 (adap1)
  • ArfGAP with dual PH domains 1 L homeolog (adap1.L)
  • ArfGAP with dual PH domains 1 (Adap1)
  • 4930431P11Rik protein
  • Centa1 protein
  • centa2 protein
  • GC1L protein
  • GCS1L protein
  • MGC76109 protein
  • p42IP4 protein

Protein level used designations for ADAP1

centaurin, alpha 1 , ArfGAP with dual PH domains 1 , Centaurin-alpha2 protein , arf-GAP with dual PH domain-containing protein 1-like , arf-GAP with dual PH domain-containing protein 1 , inositol(1,3,4,5)tetrakisphosphate receptor , centaurin-alpha , centaurin-alpha-1 , cnt-a1 , putative MAPK-activating protein PM25

GENE ID SPECIES
416451 Gallus gallus
394901 Xenopus (Silurana) tropicalis
495044 Xenopus laevis
696246 Macaca mulatta
750938 Pan troglodytes
100410764 Callithrix jacchus
100472030 Ailuropoda melanoleuca
100558369 Anolis carolinensis
397453 Sus scrofa
11033 Homo sapiens
231821 Mus musculus
606942 Canis lupus familiaris
171097 Rattus norvegicus
282176 Bos taurus
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