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ASAP2 Proteins

4 results:

ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 2 (ASAP2) (AA 1-1006) protein (His tag) Protein

Crystallography grade ASAP2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3089284
$15,464.90
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 70 Business Days

ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 2 (ASAP2) (AA 1-958) protein (His tag) Protein

Crystallography grade ASAP2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3135911
$15,464.90
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 70 Business Days

ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 2 (ASAP2) (AA 1-1006) protein (GST tag) Protein

ASAP2 Origin: Human Host: Wheat germ Recombinant AA, AP, ELISA, WB
Catalog No. ABIN1345787
$574.29
Plus shipping costs $45.00 and $24.00 dry ice
10 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 2 (ASAP2) (AA 909-1006) protein (GST tag) Protein

ASAP2 Origin: Human Host: Wheat germ Recombinant AA, AP, ELISA, WB
Catalog No. ABIN1345789
$574.29
Plus shipping costs $45.00 and $24.00 dry ice
10 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days
  • Type Protein
    • Protein
  • Target ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 2 (ASAP2)
    • ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 2 (ASAP2)
    • Hemagglutinin (HA)
    • Hemoglobin beta (HBB)
    • Ribosome Binding Factor A (RBFA)
    • Triosephosphate Isomerase 1 (TPI1)
    • S-Adenosyl-Methionine Synthase (METK)
    • Hemoglobin, alpha 1 (HBA1)
    • Myoglobin (MB)
    • Tumor Necrosis Factor alpha (TNF alpha)
    • Thymidylate Kinase (Tmk)
    • Lipoyl synthase lipA
    • Growth Hormone 1 (GH1)
    • Interferon gamma (IFNG)
    • Aspartate Carbamoyltransferase (PYRB)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • Uracil-DNA Glycosylase (UNG)
    • Malate Dehydrogenase (MDH)
    • Phosphoglucosamine Mutase (GLMM)
    • SARS-CoV-2 Spike
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • phosphatidylserine Decarboxylase (PISD)
    • Cysteinyl-tRNA Synthetase 2, Mitochondrial (Putative) (CARS2)
    • tRNA Methyltransferase 5 Homolog (S. Cerevisiae) (TRMT5)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • Interleukin 6 (IL6)
    • Interleukin 2 (IL2)
    • Cytochrome C, Somatic (CYCS)
    • Interleukin 4 (IL4)
    • CD40 Ligand (CD40LG)
    • Gp120
    • Porphobilinogen Deaminase (HEMC)
    • Plasminogen Activator Inhibitor 1 (SERPINE1)
    • Superoxide Dismutase 1, Soluble (SOD1)
    • Epidermal Growth Factor Receptor (EGFR)
    • 1-(5-Phosphoribosyl)-5-[(5-Phosphoribosylamino)methylideneamino] Imidazole-4-Carboxamide Isomerase (APG10)
    • Interleukin 10 (IL10)
    • Interleukin 8 (IL8)
    • Interleukin 1, beta (IL1B)
    • Prolactin (PRL)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • Adenosylhomocysteinase (AHCY)
    • Ferrochelatase, HEMH (HEMH)
    • Thymidylate Synthase (THYA)
    • SARS-CoV-2 Spike S1
    • Uracil Phosphoribosyltransferase (UPP)
    • beta-2-Microglobulin (B2M)
    • Thymidine Kinase 1, Soluble (TK1)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Programmed Cell Death 1 (PDCD1)
    • Ribonuclease, RNase A Family, 1 (Pancreatic) (RNASE1)
    • Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
  • Application
    • ELISA
    • Western Blotting (WB)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • SDS-PAGE (SDS)
    • Crystallization (Crys)
  • Reactivity
    • Human
    • Mouse
  • Images available
  • Host
    • Insect Cells
    • Wheat germ
  • Binding Specificity
    • AA 1-1006
    • AA 1-958
    • AA 909-1006
  • Conjugate
    • Un-conjugated
    • GST tag
    • His tag
  • Protein Type
    • Recombinant
  • Format
    • Liquid
  • Grade
    • Crystallography grade

ASAP2 Protein Profile

Protein Summary

This gene encodes a multidomain protein containing an N-terminal alpha-helical region with a coiled-coil motif, followed by a pleckstrin homology (PH) domain, an Arf-GAP domain, an ankyrin homology region, a proline-rich region, and a C-terminal Src homology 3 (SH3) domain. The protein localizes in the Golgi apparatus and at the plasma membrane, where it colocalizes with protein tyrosine kinase 2-beta (PYK2). The encoded protein forms a stable complex with PYK2 in vivo. This interaction appears to be mediated by binding of its SH3 domain to the C-terminal proline-rich domain of PYK2. The encoded protein is tyrosine phosphorylated by activated PYK2. It has catalytic activity for class I and II ArfGAPs in vitro, and can bind the class III Arf ARF6 without immediate GAP activity. The encoded protein is believed to function as an ARF GAP that controls ARF-mediated vesicle budding when recruited to Golgi membranes. In addition, it functions as a substrate and downstream target for PYK2 and SRC, a pathway that may be involved in the regulation of vesicular transport. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ASAP2

  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (ASAP2) antibody
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 L homeolog (asap2.L) antibody
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 1b (asap1b) antibody
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (asap2) antibody
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (Asap2) antibody
  • 6530401G17Rik antibody
  • AMAP2 antibody
  • asap2 antibody
  • CENTB3 antibody
  • Ddef2 antibody
  • Gm592 antibody
  • Gm1523 antibody
  • PAG3 antibody
  • PAP antibody
  • Pap-alpha antibody
  • SHAG1 antibody
  • si:dkey-37o8.2 antibody

Protein level used designations for ASAP2

development and differentiation enhancing factor 2 , development- and differentiation-enhancing factor 2 , ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 , asap1 , PYK2 C terminus-associated protein , arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 , centaurin, beta 3 , development and differentiation-enhancing factor 2 , paxillin-associated protein with ARF GAP activity 3 , pyk2 C-terminus-associated protein

GENE ID SPECIES
768599 Gallus gallus
100072516 Equus caballus
431962 Xenopus laevis
459014 Pan troglodytes
475659 Canis lupus familiaris
565859 Danio rerio
618009 Bos taurus
699774 Macaca mulatta
100411588 Callithrix jacchus
100440164 Pongo abelii
100548947 Meleagris gallopavo
100560107 Anolis carolinensis
100604148 Nomascus leucogenys
8853 Homo sapiens
211914 Mus musculus
362719 Rattus norvegicus

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