anti-Artemin (ARTN) Antibodies

The protein encoded by ARTN is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. Additionally we are shipping ARTN Proteins (31) and ARTN Kits (22) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ARTN 9048 Q5T4W7
ARTN 11876 Q9Z0L2
ARTN 362572 Q6AYE8
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Top anti-ARTN Antibodies at

Showing 10 out of 116 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL 2 to 3 Days
Human Goat Un-conjugated ELISA, WB   100 μg 6 to 7 Days
Human Rabbit Un-conjugated IHC, IHC (p), WB Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg 11 to 14 Days
Cow Goat Un-conjugated ELISA, WB 100 μg 11 to 14 Days
Human Rabbit Un-conjugated IHC (p), WB Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg 6 to 8 Days
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti Annexin A13 Polyclonal Antibody, Unconjugated (ABIN724250) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL 3 to 7 Days
Mouse Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Mouse Placenta lysate; Primary Ab: 1µg/ml Rabbit Anti-Mouse ARTN Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg 15 to 18 Days
Human Rabbit Un-conjugated ELISA, IHC (p)   100 μL Available
Rat Rabbit Un-conjugated ICC, IHC, WB Figure.DAB staining on IHC-P. Samples: Rat Tissue 100 μg 15 to 18 Days
Human Rabbit Un-conjugated ELISA, WB 100 μg 11 to 14 Days

Top referenced anti-ARTN Antibodies

  1. Human Polyclonal ARTN Primary Antibody for ELISA, WB - ABIN4281738 : Pandey, Qian, Kang, Perry, Mitchell, Yin, Wu, Liu, Zhu, Lobie: Artemin stimulates oncogenicity and invasiveness of human endometrial carcinoma cells. in Endocrinology 2010 (PubMed)

  2. Human Polyclonal ARTN Primary Antibody for ELISA, WB - ABIN2477499 : Baloh, Tansey, Lampe, Fahrner, Enomoto, Simburger, Leitner, Araki, Johnson, Milbrandt: Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex. in Neuron 1999 (PubMed)
    Show all 2 Pubmed References

More Antibodies against ARTN Interaction Partners

Human Artemin (ARTN) interaction partners

  1. In human skin, either with or without atopic dermatitis (AD), there was negative correlation between the staining intensity of HSD11beta1 and ARTN. The mechanism of skin sensitivity in AD could be explained partly by decreased HSD11beta1 expression and subsequent ARTN overexpression.

  2. Artemin induced CXCR4 expression.

  3. Artemin could promote the proliferation and invasiveness of lung cancer cells in vitro and therefore could be a new potential target to combat lung cancer.

  4. The data suggest that ARTN and MMP-9 are involved in the occurrence, development, invasion and metastasis of EC, and play a synergistic role in the development of EC and lymphatic metastasis.

  5. AhR activation and ARTN expression were positively correlated in the epidermis of patients with atopic dermatitis.

  6. Report the activity, pharmacokinetics, conformational dynamics and biophysical properties of different glycoforms of ART.

  7. High ARTN increased xenograft tumor size and metastasis in hepatocellular carcinoma.

  8. Artemin expression promotes invasiveness and neurotrophic function of pancreatic adenocarcinoma cells in vivo and in vitro

  9. mRNA expression of Artemin (Artn) in the tongue mucosa of patients with burning mouth syndrome was significantly higher than that of control subjects.

  10. This is the first report of increased levels of a neurotrophic factor and of a glial cell line-derived neurotrophic factor family member in GAD patients.

  11. conclude that ARTN is one mediator of acquired resistance to trastuzumab in HER2-positive mammary carcinoma cells

  12. The expression of GFRalpha1 and/or GFRalpha3, especially when combined with ARTN expression, may be useful predictors of disease progression and outcome in specific subtypes of mammary carcinoma.

  13. ARTEMIN promotes de novo angiogenesis in ER negative mammary carcinoma through activation of TWIST1-VEGF-A signaling.

  14. ARTN promotion of the cancer stem cell-like cell phenotype was mediated by TWIST1 regulation of BCL-2 expression.

  15. High artemin promotes motility and invasiveness of pancreatic cancer.

  16. artemin lowers the threshold of temperature-dependent itch sensation.

  17. ARTN and TWIST1 synergize to produce a worse outcome in ER-MC and combined inhibition of ARTN and phosphatidylinositol 3-kinase/protein kinase B (PI3K/AKT) may therefore provide a novel therapeutic strategy in this subtype of mammary carcinoma.

  18. Presenting an efficient method for the recombinant bacterial production of large quantities of highly pure, biologically active ARTN for in vitro and in vivo studies.

  19. Studies indicate that artemin was highly expressed in squamous cell carcinoma lung cancer.

  20. These results reveal that ARTN, a known tumor metastasis-related gene, is a direct target of miR-223.

Mouse (Murine) Artemin (ARTN) interaction partners

  1. HGF supports hindlimb motor neurons through c-Met; CNTF supports subsets of axial motor neurons through CNTFRalpha; and Artemin acts as the first survival factor for parasympathetic preganglionic motor neurons through GFRalpha3/Syndecan-3 activation.

  2. RET coupling to ERK and Akt depends strongly on artemin concentration, and it is highest at the low (~100 pM) artemin levels required for neurite outgrowth.

  3. We found that artemin, the specific GFRalpha3 ligand that evokes heat hyperalgesia, robustly sensitized cold responses in a TRPM8-dependent manner in mice.

  4. artemin lowers the threshold of temperature-dependent itch sensation.

  5. a role for the glial-derived neurotrophic factor ARTN in mood disorders is suggested.

  6. Increase in levels of artemin and GFRalpha3 regulates C-fiber recruitment after axotomy and regeneration.

  7. Artemin-deficient mice revealed abnormalities in the migration and axonal projection pattern of the sympathetic nervous system. Artemin guides sympathetic fibers in following blood vessels as they project toward their final targets.

  8. The level of artemin in the skin modulates gene expression and response properties of afferents that project to the skin and these changes lead to behavioral sensitivity to both hot and cold stimuli.

  9. These results suggest a potential role for artemin-responsive sensory afferents in mediating sensitivity associated with tissue injury

  10. Data report an autocrine/paracrine role of the artemin-GFRA3 signaling system in regulating early embryonic development and apoptosis.

ARTN Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-Artemin (ARTN) Antibodies

  • artemin (ARTN) antibody
  • artemin (Artn) antibody
  • ARTN antibody
  • ENOVIN antibody
  • EVN antibody
  • NBN antibody
  • neublastin antibody

Protein level used designations for anti-Artemin (ARTN) Antibodies

artemin , neurotrophic factor artemin , neublastin , neurotrophic factor

469310 Pan troglodytes
701641 Macaca mulatta
9048 Homo sapiens
11876 Mus musculus
362572 Rattus norvegicus
100719457 Cavia porcellus
530812 Bos taurus
100857910 Gallus gallus
100624603 Sus scrofa
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