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The protein encoded by BCL2L12 belongs to the BCL-2 protein family. Additionally we are shipping BCL2L12 Proteins (5) and and many more products for this protein.
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stress hormone cortisol suppresses p53 (show TP53 Antibodies) in hepatocellular carcinoma via enhancing Bcl2L12 expression
TNF-alpha (show TNF Antibodies) suppresses IL-10 (show IL10 Antibodies) in peripheral B cells via up-regulating Bcl2L12 in patients with ulcerative colitis.
miR (show MLXIP Antibodies)-125a-5p inhibits cell proliferation and induces apoptosis in colon cancer cells via targeting BCL2 (show BCL2 Antibodies), BCL2L12 and Mcl-1 (show MCL1 Antibodies).
Identify 50 novel BCL2L12 splice variants in human tumor cell lines.
Results show that high Bcl2L12 mRNA expression was associated with the high-grade breast cancer and triple-negative (TNBC) subtype. Also, the interplay between Bcl2L12 and its variant may be associated with high lymph node metastasis in non-TNBC tumors.
CD82 (show CD82 Antibodies) regulated BCL2L12 expression via STAT5A (show STAT5A Antibodies) and AKT (show AKT1 Antibodies) signaling and stimulated proliferation and engrafting of leukemia cells.
Bcl2L12 retains a BH3-like domain, which is important for its anti-apoptotic property.
Data indicate that BCL2-like 12 (proline rich) protein (show C4BPA Antibodies) BCL2L12 mRNA levels can distinguish women with breast cancer from healthy controls.
Data indicate that BCL2L12 expression levels were associated with poor disease-free survival of the high-grade TaT1 bladder cancer patients.
Bcl2L12 was previously shown to inhibit apoptosis through binding to caspase 7 (show CASP7 Antibodies).
nuclear Bcl2L12 physically and functionally interacts with the p53 tumor suppressor (show TP53 Antibodies)
Data show that apoptotic defect in Irf3 (show IRF3 Antibodies)(-/-)Bcl2l12(-/-) MEFs was rescued by the ectopic expression of Bcl2L12, but not IRF3 (show IRF3 Antibodies).
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a Bcl-2 homology domain 2 (BH2). The function of this gene has not yet been determined. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Bcl-2 related proline-rich protein
, bcl-2-like protein 12
, bcl-2-related proline-rich protein