BCL2-Like 12 (Proline Rich) Proteins (BCL2L12)

The protein encoded by BCL2L12 belongs to the BCL-2 protein family. Additionally we are shipping BCL2L12 Antibodies (63) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
BCL2L12 83596 Q9HB09
Mouse BCL2L12 BCL2L12 75736  
Rat BCL2L12 BCL2L12 361567  
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Top BCL2L12 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,749.58
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Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 11 Days
$888.80
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Escherichia coli (E. coli) Human GST tag 100 μg Log in to see 14 to 16 Days
$505.35
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BCL2L12 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,

More Proteins for BCL2-Like 12 (Proline Rich) (BCL2L12) Interaction Partners

Human BCL2-Like 12 (Proline Rich) (BCL2L12) interaction partners

  1. Activation of PAR2 inhibits the expression of IL-10 in B cells, which can be reversed by treating B cells with Bcl2L12 shRNA-carrying liposomes.

  2. BCL2L12 is a new prognostic biomarker for favorable outcome in diffuse large B-cell lymphoma patients on rituximab.

  3. stress hormone cortisol suppresses p53 in hepatocellular carcinoma via enhancing Bcl2L12 expression

  4. TNF-alpha suppresses IL-10 in peripheral B cells via up-regulating Bcl2L12 in patients with ulcerative colitis.

  5. miR-125a-5p inhibits cell proliferation and induces apoptosis in colon cancer cells via targeting BCL2, BCL2L12 and Mcl-1.

  6. Identify 50 novel BCL2L12 splice variants in human tumor cell lines.

  7. Results show that high Bcl2L12 mRNA expression was associated with the high-grade breast cancer and triple-negative (TNBC) subtype. Also, the interplay between Bcl2L12 and its variant may be associated with high lymph node metastasis in non-TNBC tumors.

  8. CD82 regulated BCL2L12 expression via STAT5A and AKT signaling and stimulated proliferation and engrafting of leukemia cells.

  9. Bcl2L12 retains a BH3-like domain, which is important for its anti-apoptotic property.

  10. Data indicate that BCL2-like 12 (proline rich) protein BCL2L12 mRNA levels can distinguish women with breast cancer from healthy controls.

  11. Data indicate that BCL2L12 expression levels were associated with poor disease-free survival of the high-grade TaT1 bladder cancer patients.

  12. Bcl2L12 was previously shown to inhibit apoptosis through binding to caspase 7.

  13. cisplatin treatment induced a time-dependent apoptosis in glioblastoma cells, at least partially via downregulation of BCL2L12 gene expression.

  14. Acute myeloid leukemia patients have a lower level of BCL2L12 gene expression.

  15. Protein made from F17F mutant BCL2L12 transcript bound p53, inhibited UV-induced apoptosis more efficiently than WT BCL2L12, and reduced endogenous p53 target gene transcription.

  16. results suggest BCL2L12 mRNA expression may serve as potential prognostic biomarker in tongue and/or larynx SCC, which principally constitute great majority of HNSCC cases worldwide.

  17. Bcl2L12 expression efficiently discriminates chronic lymphocytic leukemia cases from healthy controls but did not reflect their clinical characteristics

  18. BCL2L12 can be considered as a new independent prognostic and chemotherapy response marker in acute myeloid leukemia.

  19. Molecular cloning of novel alternatively spliced variants of BCL2L12, a new member of the BCL2 gene family, and their expression analysis in cancer cells.

  20. The BCL2L12(153-191) fragment directly interrupted GSK3beta mediated Tau phosphorylation.

Mouse (Murine) BCL2-Like 12 (Proline Rich) (BCL2L12) interaction partners

  1. nuclear Bcl2L12 physically and functionally interacts with the p53 tumor suppressor

  2. Data show that apoptotic defect in Irf3(-/-)Bcl2l12(-/-) MEFs was rescued by the ectopic expression of Bcl2L12, but not IRF3.

BCL2L12 Protein Profile

Protein Summary

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a Bcl-2 homology domain 2 (BH2). The function of this gene has not yet been determined. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Gene names and symbols associated with BCL2L12

  • BCL2 like 12 (BCL2L12)
  • BCL2-like 12 (proline rich) (Bcl2l12)
  • BCL2 like 12 (Bcl2l12)
  • 2810475P17Rik protein
  • 5430429M05Rik protein
  • Bcl-L12 protein
  • Bcl2-L12 protein

Protein level used designations for BCL2L12

Bcl-2 related proline-rich protein , bcl-2-like protein 12 , bcl-2-related proline-rich protein , bcl2-L-12

GENE ID SPECIES
83596 Homo sapiens
100688537 Canis lupus familiaris
533338 Bos taurus
75736 Mus musculus
361567 Rattus norvegicus
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