anti-BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI) Antibodies

BAMBI encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. Additionally we are shipping BAMBI Kits (12) and BAMBI Proteins (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BAMBI 25805 Q13145
BAMBI 83837 Q91XN4
BAMBI 68010 Q9D0L6
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Top anti-BAMBI Antibodies at antibodies-online.com

Showing 10 out of 68 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Chicken Rabbit Un-conjugated WB Western blot analysis of BAMBI expression in HEK293T (A), Raw264.7 (B) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated FACS, IF (p), IHC (p), WB L1 rat brain lysates L2 rat kidney lysates probed with Anti BAMBI Polyclonal Antibody, Unconjugated (ABIN1714490) at 1:200 overnight at 4 °C. Followed by conjugation to secondary antibody at 1:3000 for 90 min at 37 °C. Predicted band 29kD. Observed band size:29kD. Mouse splenocytes probed with Rabbit Anti-BAMBI Polyclonal Antibody, Unconjugated . 100 μL 14 to 21 Days
$329.45
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL 14 to 16 Days
$247.82
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts from Hela, using BAMBI antibody. Lane 1 was treated with the blocking peptide. ABIN6273199 at 1/100 staining Human lymph cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, IHC (p), WB Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg 11 to 14 Days
$616.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot analysis of BAMBI expression in transfected 293T cell line by BAMBI monoclonal antibody (M01), clone 3C1-1D1.Lane 1: BAMBI transfected lysate(29.1 KDa).Lane 2: Non-transfected lysate. Detection limit for recombinant GST tagged BAMBI is 3 ng/ml as a capture antibody. 100 μg 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Recombinant protein. Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μg 13 to 16 Days
$350.00
Details
Human Rabbit Un-conjugated ELISA, IF, IHC (p), WB   0.1 mg 2 to 3 Days
$360.00
Details
Human Rabbit Un-conjugated IF/ICC, WB Western blot analysis of extracts of various cell lines, using BAMBI antibody (ABIN5973916) at 1/1000 dilution. Immunofluorescence analysis of HeLa cells using BAMBI antibody (ABIN5973916). Blue: DAPI for nuclear staining. 100 μL 11 to 16 Days
$426.40
Details
Human Rabbit Un-conjugated ELISA   100 μL 14 to 16 Days
$183.12
Details

Top referenced anti-BAMBI Antibodies

  1. Human Monoclonal BAMBI Primary Antibody for ELISA, WB - ABIN565170 : Tramullas, Lantero, Díaz, Morchón, Merino, Villar, Buscher, Merino, Hurlé, Izpisúa-Belmonte, Hurlé: BAMBI (bone morphogenetic protein and activin membrane-bound inhibitor) reveals the involvement of the transforming growth factor-beta family in pain modulation. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal BAMBI Primary Antibody for FACS, IF (p) - ABIN1714490 : Bai, Chu, Mai, Zheng, Wang, Zhang, Yang: Identification and expression analyses of BAMBI mediated by FSH in swine luteinizing granulosa cells. in Theriogenology 2014 (PubMed)
    Show all 3 Pubmed References

More Antibodies against BAMBI Interaction Partners

Human BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI) interaction partners

  1. overexpression of BAMBI could decrease the ability of M2 macrophages to induce Treg differentiation

  2. BAMBI expression is reduced in ALS4 patients due to methylation of promoter caused by decreased formation of R-loops due to mutation in senataxin (SETX) gene.

  3. human BAMBI may function as a molecular switch to control TGFbeta signalling strength and the Th17/Treg cell balance

  4. BAMBI promotes macrophage proliferation and differentiation in gliomas.

  5. These results showed that BMP2 activated SMAD1/5/8 phosphorylation and up-regulated BAMBI mRNA in human granulosa-lutein cells.

  6. Data show that BAMBI is expressed in both circulating CD4+ T cells and plasma and may be characterized as a novel immune regulator for COPD. Strikingly, BAMBI expression was significantly stronger in COPD patients and displayed strong correlations with enhanced plasma TGF-beta 1 levels and the Th17/Treg ratio.

  7. Lipopolysaccharides-mediated TLR4 signaling enhances TGF-beta response through downregulating BAMBI during prostatic hyperplasia.

  8. Low BAMB1 expression is associated with Non-Small Cell Lung Cancer.

  9. TGFbeta target genes including TGFBI, BAMBI, COL3A1 and SERPINE1 are significantly increased in Diamond Blackfan Anemia induced pluripotent stem cells

  10. The observations illuminated that BAMBI inhibits adipogenesis by a feedback loop (BAMBI-->beta-catenin nuclear translocation-->BAMBI), which forms with Wnt/beta-catenin signaling.

  11. betacatenin expression was downregulated as a result of knocking down of BAMBI, and TGF-beta was downregulated in a similar manner.

  12. BAMBI alone or in combination with Smad7 was significantly associated with the OS and DFS. These findings suggest that BAMBI and Smad7 may cooperatively inhibit the TGF-beta signaling, and thus promote the progression of gastric cancer.

  13. study demonstrates that LPS- and TNF-alpha-induced NF-kappaBp50-HDAC1 interaction represses BAMBI transcriptional activity, which contributes to TLR4-mediated enhancement of TGF-beta signaling in hepatic stellate cells during liver fibrosis.

  14. Overexpression of BAMBI is associated with the growth and invasion of human osteosarcoma.

  15. Metformin-mediated Bambi expression in hepatic stellate cells induces prosurvival Wnt/beta-catenin signaling

  16. Alterations in BAMBI may play a role in the (patho)physiology of obesity, and manipulation of BAMBI may present a novel therapeutic approach to improve adipose tissue function.

  17. Data show that hepatoprotective effects of adiponectin include induction of BAMBI which is reduced in human fatty liver.

  18. BAMBI protein is expressed in endothelial cells and is regulated by autophagy and lysosomal degradation.

  19. Expression of the TGF pseudoreceptor BAMBI in the human lung, which is upregulated in response to nontypeable Haemophilus influenzae infection in COPD lung tissue in vivo and in vitro.

  20. Authors demonstrate for the first time a nuclear co-translocation of BAMBI with Smad2/3 upon TGF-geta treatment. Moreover, overexpression of BAMBI in an in vitro model led to significantly increased proliferation.

Pig (Porcine) BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI) interaction partners

  1. results indicated that BMP and activin membrane-bound inhibitor homolog(BAMBI) is an FSH-repressed gene in porcine luteinizing granulosa cells and it may be involved in the regulation of ovarian follicle development and oocyte maturation

Zebrafish BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI) interaction partners

  1. This study shows that upregulation of bigh3 and bambia mRNA correlated with the process of fin regeneration and regulation of TGF-b signaling, suggesting a new role for these proteins.

Mouse (Murine) BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI) interaction partners

  1. Comparing with the cytosolic trapping in resting muscle, BAMBI protein is enriched on cellular membrane during the muscle growth and regeneration, suggesting that BAMBI-mediated a significant signaling pathway may be an essential part of muscle growth and regeneration.

  2. BAMBI is required for normal C2C12 differentiation, and that its role in myogenesis is mediated by the Wnt/beta-catenin pathway.

  3. BAMBI modulates the effects of diabetes on glomerular permselectivity in association with altered ERK1/2 and Smad1/5 signaling.

  4. these results provide strong evidence for an important role of endothelium rather than platelet BAMBI as a positive regulator of both thrombus formation and stability.

  5. we provide in vitro and in vivo evidence that BAMBI contributes to endothelial and vascular homeostasis

  6. suggest that BAMBI is involved in negative feedback loops that restrain the TGF-beta remodeling signals to protect the pressure-overloaded myocardium from uncontrolled extracellular matrix deposition in humans and mice

  7. BAMBI protein is expressed in endothelial cells and is regulated by autophagy and lysosomal degradation.

  8. Transcript levels of TGF-betas and their intracellular effectors correlated directly with genes encoding opioid peptides, whereas BAMBI correlated inversely.

  9. Overexpression of Nma/BAMBI in mouse odontoblast-like cell line MD10-A2 down-regulated expression of DSPP by 66% and up-regulated expression of DMP1 four-fold.

  10. and has implications in tumor progression. Genomic organization of the mouse Nma/BAMBI gene and confirmed the chromosomal mapping to human chromosome 10 and mouse chromosome 2.

BAMBI Antigen Profile

Protein Summary

This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis.

Gene names and symbols associated with BAMBI

  • BMP and activin membrane bound inhibitor (BAMBI) antibody
  • BMP and activin membrane-bound inhibitor homolog (bambi) antibody
  • BMP and activin membrane-bound inhibitor (bambi) antibody
  • BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a (bambia) antibody
  • BMP and activin membrane-bound inhibitor (Bambi) antibody
  • BMP and activin membrane-bound inhibitor homolog (LOC724378) antibody
  • BMP and activin membrane bound inhibitor (bambi) antibody
  • BMP and activin membrane-bound inhibitor homolog (LOC100647353) antibody
  • BMP and activin membrane-bound inhibitor L homeolog (bambi.L) antibody
  • 2610003H06Rik antibody
  • BAMBI antibody
  • bambi-A antibody
  • cb998 antibody
  • fc44c12 antibody
  • id:ibd5020 antibody
  • nma antibody
  • wu:fc44c12 antibody
  • wu:fe01e03 antibody
  • Zfnma antibody

Protein level used designations for BAMBI

BMP and activin membrane-bound inhibitor homolog , non-metastatic gene A protein , putative transmembrane protein NMA , BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) , etID64300.12 , BMP and activin membrane-bound inhibitor, homolog , kinase-deficient TGFbeta superfamily receptor subunit , BAMBI protein (TGF-beta signalling) , BMP and activin membrane-bound inhibitor L homeolog

GENE ID SPECIES
25805 Homo sapiens
449001 Sus scrofa
100302750 Saccoglossus kowalevskii
100482525 Ailuropoda melanoleuca
428413 Gallus gallus
487081 Canis lupus familiaris
493556 Xenopus (Silurana) tropicalis
710152 Macaca mulatta
745034 Pan troglodytes
83496 Danio rerio
83837 Rattus norvegicus
443242 Ovis aries
724378 Apis mellifera
100540171 Meleagris gallopavo
100554299 Anolis carolinensis
100606459 Nomascus leucogenys
100647353 Bombus terrestris
68010 Mus musculus
530147 Bos taurus
394401 Xenopus laevis
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