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BRSK1 Proteins

Serine/threonine-protein kinase that plays a key role in polarization of neurons and centrosome duplication.

6 results:

BR Serine/threonine Kinase 1 (BRSK1) (AA 1-778) protein (His tag) Protein

BRSK1 Origin: Mouse Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3135216
$15,464.90
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 70 Business Days

BR Serine/threonine Kinase 1 (BRSK1) (AA 1-778) protein (His tag) Protein

BRSK1 Origin: Human Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3090446
$15,464.90
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 70 Business Days

BR Serine/threonine Kinase 1 (BRSK1) (AA 1-778) protein (GST tag) Protein

BRSK1 Origin: Human Source: Insect Cells Recombinant Func, SDS
Catalog No. ABIN5570636
$676.00
Plus shipping costs $45.00
5 μg
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

BR Serine/threonine Kinase 1 (BRSK1) (AA 289-380) protein (GST tag) Protein

BRSK1 Origin: Human Source: Wheat germ Recombinant AA, AP, ELISA, WB
Catalog No. ABIN1346887
$574.29
Plus shipping costs $45.00 and $24.00 dry ice
10 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

BR Serine/threonine Kinase 1 (BRSK1) (Active) protein (GST tag) Protein

BRSK1 Origin: Mouse Source: Insect Cells Recombinant 70 % - 90 % Func
Catalog No. ABIN5509205
$310.00
Plus shipping costs $45.00
10 μg
local_shipping Shipping to: United States
Delivery in 3 to 4 Business Days

BR Serine/threonine Kinase 1 (BRSK1) (AA 1-778) protein (His tag) Protein

BRSK1 Origin: Rat Source: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1670475
$4,282.67
Plus shipping costs $45.00
1 mg
local_shipping Shipping to: United States
Delivery in 57 to 68 Business Days
  • Type Protein
    • Protein
  • Target BR Serine/threonine Kinase 1 (BRSK1)
    • BR Serine/threonine Kinase 1 (BRSK1)
    • Hemagglutinin (HA)
    • Ribosome Binding Factor A (RBFA)
    • Tumor Necrosis Factor alpha (TNF)
    • S-Adenosyl-Methionine Synthase (METK)
    • Interleukin 6 (IL6)
    • Interferon gamma (IFNG)
    • Hemoglobin beta (HBB)
    • Triosephosphate Isomerase 1 (TPI1)
    • Thymidylate Kinase (Tmk)
    • Interleukin 4 (IL4)
    • Interleukin 1, beta (IL1B)
    • Interleukin 2 (IL2)
    • Uracil-DNA Glycosylase (UNG)
    • Fibroblast Growth Factor 2 (Basic) (FGF2)
    • Lipoyl synthase lipA
    • Growth Hormone 1 (GH1)
    • Interleukin 10 (IL10)
    • KIT Ligand (KITLG)
    • Malate Dehydrogenase (MDH)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Epidermal Growth Factor (EGF)
    • Leptin (LEP)
    • Interleukin 8 (IL8)
    • Interleukin 3 (IL-3)
    • Myoglobin (MB)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • Hemoglobin, alpha 1 (HBA1)
    • serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1)
    • phosphatidylserine Decarboxylase (PISD)
    • Interleukin 1 alpha (IL1A)
    • CD40 Ligand (CD40LG)
    • Prolactin (PRL)
    • Interleukin 13 (IL13)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • Chemokine (C-X-C Motif) Ligand 12 (CXCL12)
    • Albumin (ALB)
    • Aspartate Carbamoyltransferase (PYRB)
    • Phosphoglucosamine Mutase (GLMM)
    • Porphobilinogen Deaminase (HEMC)
    • Interleukin 15 (IL15)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • beta-2-Microglobulin (B2M)
    • Chemokine (C-C Motif) Ligand 2 (CCL2)
    • Gp120
    • Interleukin 33 (IL33)
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • Fibroblast Growth Factor 1 (Acidic) (FGF1)
    • Adiponectin (ADIPOQ)
    • Ferrochelatase, HEMH (HEMH)
  • Application
    • ELISA
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • Functional Studies (Func)
    • Crystallization (Crys)
    • Affinity Purification (AP)
    • Antibody Array (AA)
  • Reactivity
    • Human
    • Mouse
    • Rat
  • Images available
  • Host
    • Insect Cells
    • Wheat germ
    • Yeast
  • Binding Specificity
    • AA 1-778
    • AA 289-380
  • Conjugate
    • Un-conjugated
    • GST tag
    • His tag
  • Protein Type
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
  • Biological Activity
    • Active

BRSK1 Protein Profile

Protein Summary

Serine/threonine-protein kinase that plays a key role in polarization of neurons and centrosome duplication. Phosphorylates CDC25B, CDC25C, MAPT/TAU, RIMS1, TUBG1, TUBG2 and WEE1. Following phosphorylation and activation by STK11/LKB1, acts as a key regulator of polarization of cortical neurons, probably by mediating phosphorylation of microtubule-associated proteins such as MAPT/TAU at 'Ser-573'. Also regulates neuron polarization by mediating phosphorylation of WEE1 at 'Ser-642' in post-mitotic neurons, leading to down-regulate WEE1 activity in polarized neurons. Also acts as a positive regulator of centrosome duplication by mediating phosphorylation of gamma-tubulin (TUBG1 and TUBG2) at 'Ser-131', leading to translocation of gamma-tubulin and its associated proteins to the centrosome. Involved in the UV- induced DNA damage checkpoint response, probably by inhibiting CDK1 activity through phosphorylation and activation of WEE1, and inhibition of CDC25B and CDC25C (By similarity). In neurons, localizes to synaptic vesicles and plays a role in neurotransmitter release, possibly by phosphorylating RIMS1.

Gene names and symbols associated with BRSK1

  • BR serine/threonine kinase 1 (BRSK1) antibody
  • BR serine/threonine kinase 1 (Brsk1) antibody
  • BRSK1 antibody
  • Gm1100 antibody
  • hSAD1 antibody
  • RGD1563268 antibody
  • Sad-b antibody
  • SADB antibody

Protein level used designations for BRSK1

BR serine/threonine kinase 1 , BR serine/threonine-protein kinase 1-like , BR serine/threonine-protein kinase 1 , SAD1 homolog , SAD1 kinase , SadB kinase short isoform , brain-selective kinase 1 , brain-specific serine/threonine-protein kinase 1 , protein kinase SAD1A , serine/threonine-protein kinase BRSK1 , serine/threonine-protein kinase SAD-B , synapses of Amphids Defective homolog 1 , serine/threonine kinase SAD-B , serine/threonine kinase SADB

GENE ID SPECIES
100055612 Equus caballus
484297 Canis lupus familiaris
700287 Macaca mulatta
100352646 Oryctolagus cuniculus
100450205 Pongo abelii
100477927 Ailuropoda melanoleuca
100610477 Pan troglodytes
84446 Homo sapiens
381979 Mus musculus
499073 Rattus norvegicus
100512610 Sus scrofa
538009 Bos taurus

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