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The C-terminus of the protein encoded by BTBD1 binds topoisomerase I. Additionally we are shipping BTBD1 Antibodies (61) and and many more products for this protein.
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Interaction of BTBD1 and BTBD2 with TOP1 requires TOP1 residues 236 and 237, the same residues required to enhance the infectivity of progeny virions when TOP1 is expressed in African Green Monkey producer cells.
subcellular colocalization of BTBD1 and BTBD2 to cytoplasmic bodies; TRIM5delta colocalized with BTBD1/2 and appeared to serve as a scaffold for the assembly of endogenous BTBD1/2 proteins
BTBD1 is essential for myogenic differentiation
BTBD1 is a key protein of balance between adipogenesis and myogenesis.
The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies. Alternative splicing results in multiple transcript variants encoding different isoforms.
BTB domain containing 1
, BTB/POZ domain-containing protein 1
, HCV NS5A-transactivated protein 8
, hepatitis C virus NS5A-transactivated protein 8
, BTB (POZ) domain containing 1
, glucose signal-repressing protein
, BTB/POZ domain-containing protein 1-like