Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM) ELISA Kits

BCAM encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. Additionally we are shipping BCAM Antibodies (99) and BCAM Proteins (16) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
BCAM 57278 Q9R069
BCAM 4059 P50895
BCAM 78958 Q9ESS6
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Top BCAM ELISA Kits at

Showing 6 out of 23 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human < 40 pg/mL 40-10000 pg/mL 96 Tests Log in to see 2 to 3 Days
Rhesus Monkey
  96 Tests Log in to see 31 to 41 Days
Mouse BCAM PicoKine ELISA Kit standard curve 96 Tests Log in to see 4 to 6 Days
Human 20 pg/mL 40.9 pg/mL - 10000 pg/mL   96 Tests Log in to see 5 to 8 Days
  96 Tests Log in to see 11 to 18 Days
  96 Tests Log in to see 15 to 18 Days

More ELISA Kits for BCAM Interaction Partners

Mouse (Murine) Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM) interaction partners

  1. Lu/BCAM may have a critical role in facilitating the accumulation of monocytes and macrophages, thereby exacerbating renal injury in crescentic glomerulonephritis.

  2. Lutheran (Lu), also known as basal cell adhesion molecule (B-CAM), competes with integrins for binding to laminin alpha5, a subunit of LM-511, a major component of basement membranes.

  3. Lu/BCAM, as a laminin receptor, is involved in vivo in the maintenance of normal basement membrane organization in the kidney and intestine.

Human Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM) interaction partners

  1. Lu expression by erythrocytes from patients with myeloproliferative neoplasms and splanchnic venous thrombosi is significantly increased compared to erythrocytes from healthy individuals

  2. This is the first report showing that Lu/BCAM, in the presence of its ligand laminin, is oncogenic in human urothelial cancers and may have potential as a novel therapeutic target.

  3. data show that the BCAM/LAMA5 system plays a functional role in the metastatic spreading of KRAS-mutant colorectal cancer

  4. The serum levels of IL-8, MIP-1 alpha, MIP-1 beta, MMP-8, Resistin, FLRG, and BCAM were significantly higher in breast cancer patients, but LAP and TSH-beta levels were lower.

  5. four new alleles with coding sequence variants were identified in the LU gene

  6. Cytometry analysis evidenced a specific expression profile on reticulocytes of SCA infants, with notably an increased expression of the adhesion molecules Lu/BCAM, ICAM-4 and LFA-3, both in percentage of positive cells and in surface density.

  7. Through molecular genotyping we also identified polymorphisms in RhCE, Kell, Duffy, Colton, Lutheran and Scianna loci in donors and patients.

  8. The variable levels of expression of mutated JAK2 and BCAM proteins determine different adhesion patterns of erythrocytes from polycythemia vera patients.

  9. These studies revealed amino acids 720 to 1014 of CNF1 as the binding site for Lu/BCAM.

  10. High BCAM expression is associated with hepatocellular carcinoma.

  11. Adhesion of sickle reticulocytes to HC-treated endothelial cells was decreased despite the HC-derived increase of Lu/BCAM expression.

  12. tumor cell migration on LM-511 requires that Lu/B-CAM competitively modulates cell attachment through integrins.

  13. DARC and BCAM expression was associated with pathogenesis of thyroid carcinoma and correlated with clinical-pathological features.

  14. Glu425 in the Lu glycoprotein is required for expression of Lu7, and Ala425 is associated with the LU:-7 phenotype. This completes the molecular basis associated with all antigens known to be in the Lutheran blood group system.

  15. Increases in adhesion frequency provide significant evidence of the role of epinephrine in BCAM/Lu-laminin and ICAM-4-alpha(v)beta(3) bonding, and suggest mechanisms of vaso-occlusion during physical exertion in sickle cell trait.

  16. Data indicate that the function-blocking antibody against Lu/B-CAM should be useful for not only investigating cell adhesion to laminin alpha5 but also for developing drugs to inhibit sickle cell vaso-occlusion.

  17. Aggregation of mononuclear and red blood cells through an {alpha}4{beta}1-Lu/basal cell adhesion molecule interaction in sickle cell disease

  18. BCAM glycoproteins are the unique erythroid receptors of laminin alpha5 chain, a major component of the extracellular matrix and are involved in several erythrocyte diseases.

  19. Results demonstrate that the alpha5 LG3 module is essential for the Lutheran blood group glycoprotein (Lu) binding to laminin alpha5.

  20. B-CAM/LU is the most critical receptor mediating adhesion to laminin under both static and flow conditions in sickle cell anemia.

BCAM Antigen Profile

Antigen Summary

This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with BCAM

  • basal cell adhesion molecule (Lutheran blood group) (bcam) antibody
  • basal cell adhesion molecule (Lutheran blood group) L homeolog (bcam.L) antibody
  • basal cell adhesion molecule (Lutheran blood group) (BCAM) antibody
  • basal cell adhesion molecule (BCAM) antibody
  • basal cell adhesion molecule (Bcam) antibody
  • basal cell adhesion molecule (Lutheran blood group) (Bcam) antibody
  • 1200005K12Rik antibody
  • AU antibody
  • B-CAM antibody
  • CD239 antibody
  • Gplu antibody
  • Lu antibody
  • MGC81012 antibody
  • MSK19 antibody
  • prr2 antibody
  • zgc:154034 antibody

Protein level used designations for BCAM

basal cell adhesion molecule (Lutheran blood group) , Auberger b antigen , Lutheran blood group , basal cell adhesion molecule (Lu and Au blood groups) , basal cell adhesion molecule , LU , basal cell adhesion molecule-like , B-CAM cell surface glycoprotein , lutheran antigen , lutheran glycoprotein , B-cell adhesion molecule , F8/G253 antigen , antigen identified by monoclonal antibody F8 , glycoprotein 95kDa , Lutheran blood group (Auberger b antigen included)

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