anti-Basigin (Ok Blood Group) (BSG) Antibodies

The protein encoded by BSG is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. Additionally we are shipping CD147 Kits (65) and CD147 Proteins (38) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BSG 682 P35613
BSG 12215 P18572
BSG 25246 P26453
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Top anti-CD147 Antibodies at antibodies-online.com

Showing 10 out of 645 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Rat Mouse Un-conjugated CyTOF, FACS, ICC, IF, IHC, IHC (fro), IHC (p), WB Immunohistochemistry-Paraffin: EMMPRIN/CD147 Antibody (OX-47) [ABIN2558558] - IHC analysis of a formalin fixed paraffin embedded (FFPE) tissue section of rat kidney using 1:100 dilution of CD147 antibody (clone OX-47). The staining was detected using HRP-labelled secondary antibody and DAB reagent which followed counterstaining of sections with hematoxylin. This antibody generated primarily a membrane staining with some cytoplasmic signal in the cuboidal epithelial cells of various tubules. Flow Cytometry: EMMPRIN/CD147 Antibody (OX-47) [ABIN2558558] - Rat Splenocytes were stained with EMMPRIN/CD147 (OX-47) antibody ABIN2558558 (blue) and a matched isotype control NBP2-27287 (orange). Cells were incubated in an antibody dilution of 1 ug/mL for 20 minutes at room temperature. The antibodies were directly conjugated to Alexa Fluor 488. 0.1 mL Log in to see 7 to 9 Days
$415.44
Details
Human Mouse FITC FACS, IHC (p), IP, WB Surface staining of human peripheral blood with anti-human CD147 (MEM-M6/1) FITC. 100 Tests Log in to see 5 to 7 Days
$316.25
Details
Horse Mouse Un-conjugated CyTOF, ELISA, FACS, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: EMMPRIN/CD147 Antibody (MEM-M6/1) [ABIN269062] - Staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. Immunohistochemistry-Paraffin: EMMPRIN/CD147 Antibody (MEM-M6/1) [ABIN269062] - Staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 0.1 mg Log in to see 12 to 15 Days
$415.44
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of CD147/Emmprin using anti-CD147/Emmprin antibody . Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each Lane was loaded with 50ug of sample under reducing conditions. Lane 1: human placenta tissue lysates, Lane 2: JURKAT whole cell lysates. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-CD147/Emmprin antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for CD147/Emmprin at approximately 55KD. The expected band size for CD147/Emmprin is at 42KD. IHC analysis of CD147/Emmprin using anti-CD147/Emmprin antibody . CD147/Emmprin was detected in paraffin-embedded section of human lung cancer tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti-CD147/Emmprin Antibody overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen. 100 μg Log in to see 4 to 6 Days
$280.00
Details
Human Mouse Biotin FACS, IHC (p), IP, WB Surface staining of human peripheral blood with anti-human CD147 (MEM-M6/1) biotin. 0.1 mg Log in to see 5 to 7 Days
$316.25
Details
Human Mouse PE FACS, IHC (p), IP, WB Surface staining of human peripheral blood with anti-human CD147 (MEM-M6/1) PE. 100 Tests Log in to see 5 to 7 Days
$366.85
Details
Human Mouse APC FACS, IHC (p), IP, WB Surface staining of human peripheral blood with anti-human CD147 (MEM-M6/1) APC. 100 Tests Log in to see 5 to 7 Days
$366.85
Details
Dog Rabbit Un-conjugated WB <b>WB Suggested Anti-BSG Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Jurkat cell lysate WB Suggested Anti-BSG <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-BSG Antibody Titration: 0.125 ug/ml Positive Control: 721_B Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated CyTOF, FACS, ICC, WB Detection of Human TRA-1-85/CD147 by Western Blot. Western blot shows lysates of human brain (cerebellum) tissue, human heart tissue, and human liver tissue. PVDF membrane was probed with 1 ug/mL of Mouse Anti-Human TRA-1-85/CD147 Monoclonal Antibody. This experiment was conducted under reducing conditions. Detection of TRA-1-85/CD147 in Human PBMCs by Flow Cytometry. Human peripheral blood lymphocytes and monocytes were stained with either (A) Mouse Anti-Human TRA-1-85/CD147 Monoclonal Antibody. 100 μg Log in to see 8 to 9 Days
$293.25
Details

Top referenced anti-CD147 Antibodies

  1. Human Monoclonal CD147 Primary Antibody for FACS - ABIN5500581 : Choi, Yu, Smuga-Otto, Salvagiotto, Rehrauer, Vodyanik, Thomson, Slukvin: Hematopoietic and endothelial differentiation of human induced pluripotent stem cells. in Stem cells (Dayton, Ohio) 2009 (PubMed)
    Show all 8 Pubmed References

  2. Rat (Rattus) Monoclonal CD147 Primary Antibody for CyTOF, FACS - ABIN4889984 : Fossum, Mallett, Barclay: The MRC OX-47 antigen is a member of the immunoglobulin superfamily with an unusual transmembrane sequence. in European journal of immunology 1991 (PubMed)
    Show all 5 Pubmed References

  3. Human Monoclonal CD147 Primary Antibody for BI, IHC (fro) - ABIN2689942 : Olivier, Rybicki, Bouhassira: Differentiation of human embryonic stem cells into bipotent mesenchymal stem cells. in Stem cells (Dayton, Ohio) 2006 (PubMed)
    Show all 4 Pubmed References

  4. Mouse (Murine) Polyclonal CD147 Primary Antibody for CyTOF, FACS - ABIN4899651 : Ramo, Cashman, Kumar-Singh: Evaluation of adenovirus-delivered human CD59 as a potential therapy for AMD in a model of human membrane attack complex formation on murine RPE. in Investigative ophthalmology & visual science 2008 (PubMed)
    Show all 4 Pubmed References

  5. Human Monoclonal CD147 Primary Antibody for CyTOF, FACS - ABIN5500590 : Lathia, Gallagher, Myers, Li, Vasanji, McLendon, Hjelmeland, Huang, Rich: Direct in vivo evidence for tumor propagation by glioblastoma cancer stem cells. in PLoS ONE 2011 (PubMed)
    Show all 3 Pubmed References

  6. Human Polyclonal CD147 Primary Antibody for FACS, IF (p) - ABIN671886 : Tsai, Chen, Huang, Lee, Ma, Huang, Sytwu, Hueng: EMMPRIN expression positively correlates with WHO grades of astrocytomas and meningiomas. in Journal of neuro-oncology 2013 (PubMed)
    Show all 2 Pubmed References

  7. Human Monoclonal CD147 Primary Antibody for FACS - ABIN2478534 : Johnston: Contributions of drug epidemiology to the field of drug abuse prevention. in NIDA research monograph 1991 (PubMed)
    Show all 4 Pubmed References

  8. Human Monoclonal CD147 Primary Antibody for FACS - ABIN2478537 : Koch, Staffler, Hüttinger, Hilgert, Prager, Cerný, Steinlein, Majdic, Horejsí, Stockinger: T cell activation-associated epitopes of CD147 in regulation of the T cell response, and their definition by antibody affinity and antigen density. in International immunology 1999 (PubMed)
    Show all 4 Pubmed References

  9. Human Monoclonal CD147 Primary Antibody for FACS, IP - ABIN2478535 : Schneiderhan, Diaz, Fundel, Zhou, Siech, Hasel, Möller, Gschwend, Seufferlein, Gress, Adler, Bachem: Pancreatic stellate cells are an important source of MMP-2 in human pancreatic cancer and accelerate tumor progression in a murine xenograft model and CAM assay. in Journal of cell science 2007 (PubMed)
    Show all 4 Pubmed References

  10. Human Monoclonal CD147 Primary Antibody for FACS - ABIN2688981 : Fadool, Linser: Evidence for the formation of multimeric forms of the 5A11/HT7 antigen. in Biochemical and biophysical research communications 1997 (PubMed)
    Show all 2 Pubmed References

More Antibodies against CD147 Interaction Partners

Cow (Bovine) Basigin (Ok Blood Group) (BSG) interaction partners

  1. Data suggest that EMMPRIN derived from endometrial epithelial cells regulates expression of matrix metalloproteinases (MMP-2 (show MMP2 Antibodies); MMP-14 (show MMP14 Antibodies)) in endometrial stromal cells; progesterone-rich conditions stimulate expression of EMMPRIN in endometrium.

  2. The selective S-nitrosylation of EMMPRIN and GOLPH3 (show GOLPH3 Antibodies) at the Golgi apparatus in endothelial cells results from the physical proximity to eNOS (show NOS3 Antibodies)-derived nitric oxide.

Human Basigin (Ok Blood Group) (BSG) interaction partners

  1. Characterization of the role of CD147 in the development of tumors should lead to a better understanding of the changes occurring at the molecular level during the development and progression of primary human bone cancer.

  2. Results find CD147 expression level increased in colorectal cancer (CRC (show CALR Antibodies)) tumors and cell lines and inversely correlated with mir (show MLXIP Antibodies)-485 expression. Also, CD147 is a target gene of miR485 which negatively regulates its gene expression.

  3. Our results indicate that concomitant stimulation and colocalization of galectin-3 (show LGALS3 Antibodies) with CD147 are associated with increased gelatinolytic activity in the actively ulcerating human cornea

  4. These findings reveal an important cytomegalovirus mechanism for evading antiviral innate immunity through its encoded microRNA US25-1-5p by targeting transmembrane glycoprotein CD147.

  5. Review: Bsg is an extracellular receptor for CyPA that promotes cell proliferation and inflammation. Thus, the CyPA/Bsg system is potentially a novel therapeutic target for cardiovascular diseases.

  6. protein-protein interaction studies on TRAF6 and BSG to get molecular level insights of the reactions.

  7. results showed that the rs4919862 SNP of CD147 was closely associated with carotid atherosclerotic plaques formation; thus, polymorphisms of the CD147 gene may be related to the tendency for carotid atherosclerotic plaques

  8. BSG mutation is associated with early-onset high myopia.

  9. Cholesterol depletion inhibits the endocytosis of CD147 but that the constitutive shedding of CD147 mediated by ADAM10 (show ADAM10 Antibodies) is enhanced.

  10. Overexpression of CD147 support the metabolic reprograming in papillary renal cell carcinoma (show MOK Antibodies)

Mouse (Murine) Basigin (Ok Blood Group) (BSG) interaction partners

  1. CD147 deletion in hepatic stellate cells alleviated CCl4 (show CCL4 Antibodies)-induced liver fibrosis and inhibited HSCs activation. Overexpression of CD147 upregulated the secretion of CXCL1 (show CXCL1 Antibodies).

  2. A new molecular mechanism for high angiogenic capacity, whereby microglia cells release basigin via up-regulation of PI3K-AKT (show AKT1 Antibodies) and IGF-1 (show IGF1 Antibodies) pathway to induce angiogenesis is unveiled.

  3. EMMPRIN inhibited bFGF (show FGF2 Antibodies)-induced IL-6 (show IL6 Antibodies) secretion by reducing the p65 (show NFkBP65 Antibodies) subunit phosphorylation, it might be concluded that bFGF (show FGF2 Antibodies) and EMMPRIN crosstalk in their respective signaling pathways.

  4. protein-protein interaction studies on TRAF6 and BSG to get molecular level insights of the reactions.

  5. This study has highlighted basigin as a common essential molecule for various stimuli-induced impairment of retinal vascular barrier, which can be a target for strategies to establish a curative treatment of diabetic retinopathy

  6. Deletion of N-linked glycosylation at Asn152 on CD147 significantly suppressed in situ tumor metastasis in hepatocellular carcinoma.

  7. MCT1 and Basigin variant-2, but not Basigin variant-1, are expressed within the mouse pineal gland.

  8. this study provided a new mechanistic concept that CD147 can be a target for lymphocyte lineage reprogramming.

  9. these results suggested that CD147 plays a key role in reducing extrinsic apoptosis in spermatocytes, but not spermatogonia, through modulating NFkappaB signaling pathway.

  10. results establish neuroplastin (show NPTN Antibodies) and basigin as obligatory auxiliary subunits of native Plasma Membrane Calcium Atpases and key regulators of intracellular Ca2 (show CA2 Antibodies)+ concentration.

Rabbit Basigin (Ok Blood Group) (BSG) interaction partners

  1. CD147 is required for the expression of MCT1 (show MCTS1 Antibodies) and MCT4 (show SLC16A3 Antibodies) in the corneal endothelium. Silencing CD147 slows lactate efflux, resulting in stromal lactate accumulation and corneal edema.

CD147 (BSG) Antigen Profile

Protein Summary

The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with BSG

  • basigin (Ok blood group) (BSG) antibody
  • basigin (Bsg) antibody
  • basigin (Ok blood group) (Bsg) antibody
  • basigin (bsg) antibody
  • basigin (Ok blood group) S homeolog (bsg.S) antibody
  • 5A11 antibody
  • 5F7 antibody
  • AI115436 antibody
  • AI325119 antibody
  • basignin antibody
  • bsg antibody
  • CD147 antibody
  • CE9 antibody
  • EMMPRIN antibody
  • HT-7 antibody
  • HT7 antibody
  • M6 antibody
  • OK antibody
  • Ox47R antibody
  • prso03 antibody
  • RPE7 antibody
  • TCSF antibody
  • wu:fb26a05 antibody
  • wu:fo98e12 antibody

Protein level used designations for BSG

basigin , CD147 antigen , OK blood group antigen , collagenase stimulatory factor , extracellular matrix metalloproteinase inducer , leukocyte activation antigen M6 , tumor cell-derived collagenase stimulatory factor , 5A11/Basigin , HT7 antigen , basic immunoglobulin superfamily , gp 42 , membrane glycoprotein gp42 , neurothelin , gp42/basigin/OX-47/HT7 , Basigin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian) , Basignin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian) , OX-47 antigen , glycoprotein CE9 , 5A11 antigen , blood-brain barrier HT7 antigen , 5A11/Basigin-2 , cd147 , basigin (Ok blood group) S homeolog

GENE ID SPECIES
508716 Bos taurus
682 Homo sapiens
12215 Mus musculus
100009229 Oryctolagus cuniculus
100141312 Sus scrofa
25246 Rattus norvegicus
770363 Gallus gallus
476758 Canis lupus familiaris
100720467 Cavia porcellus
337692 Danio rerio
100689246 Cricetulus griseus
734661 Xenopus laevis
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