anti-Basigin (Ok Blood Group) (BSG) Antibodies

The protein encoded by BSG is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. Additionally we are shipping CD147 Kits (69) and CD147 Proteins (38) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BSG 682 P35613
BSG 12215 P18572
BSG 25246 P26453
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Top anti-CD147 Antibodies at antibodies-online.com

Showing 10 out of 645 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of CD147/Emmprin using anti-CD147/Emmprin antibody .  Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.   Lane 1: human placenta tissue lysates,  Lane 2: JURKAT whole cell lysates. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-CD147/Emmprin antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for CD147/Emmprin at approximately 55KD. The expected band size for CD147/Emmprin is at 42KD. IHC analysis of CD147/Emmprin using anti-CD147/Emmprin antibody . CD147/Emmprin was detected in paraffin-embedded section of human lung cancer tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti-CD147/Emmprin Antibody  overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen. 100 μg Log in to see 4 to 6 Days
$280.00
Details
Human Rabbit Un-conjugated WB Anti-CD147 antibody, Western blotting WB: Human Fibroma Cell Lysate 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated FACS, WB Anti- CD147 Picoband antibody, Western blotting All lanes: Anti CD147  at 0.5ug/ml Lane 1: Human Placenta Tissue Lysate at 50ug Lane 2: JURKAT Whole Cell Lysate at 40ug Lane 3: U20S Whole Cell Lysate at 40ug Predicted bind size: 42KD Observed bind size: 42KD Anti- CD147 Picoband antibody, Western blotting All lanes: Anti CD147  at 0.5ug/ml WB: Recombinant Human CD147 Protein 0.5ng Predicted bind size: 39KD Observed bind size: 39KD 100 μg Log in to see 4 to 6 Days
$280.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-BSG Antibody Titration: 0.125 ug/ml Positive Control: 721_B Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-BSG Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate WB Suggested Anti-BSG  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated FACS, IF, IHC, IHC (p), WB 100 μL Log in to see 11 to 14 Days
$507.83
Details
Human Mouse Un-conjugated IF, IHC, IHC (p), WB 100 μL Log in to see 11 to 14 Days
$507.83
Details
Horse Mouse Un-conjugated CyTOF, ELISA, FACS, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: EMMPRIN/CD147 Antibody (MEM-M6/1) [ABIN269062] - Staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. Immunohistochemistry-Paraffin: EMMPRIN/CD147 Antibody (MEM-M6/1) [ABIN269062] - Staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 0.1 mg Log in to see 12 to 15 Days
$418.10
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of CD147 staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of CD147 expression in A431 (A), HeLa (B), Raw264.7 (C), mouse heart (D) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Rat Mouse Un-conjugated CyTOF, FACS, ICC, IF, IHC, IHC (fro), IHC (p), WB Immunohistochemistry-Paraffin: EMMPRIN/CD147 Antibody (OX-47) [ABIN2558558] - IHC analysis of a formalin fixed paraffin embedded (FFPE) tissue section of rat kidney using 1:100 dilution of CD147 antibody (clone OX-47). The staining was detected using HRP-labelled secondary antibody and DAB reagent which followed counterstaining of sections with hematoxylin. This antibody generated primarily a membrane staining with some cytoplasmic signal in the cuboidal epithelial cells of various tubules. Flow Cytometry: EMMPRIN/CD147 Antibody (OX-47) [ABIN2558558] - Rat Splenocytes were stained with EMMPRIN/CD147 (OX-47) antibody ABIN2558558 (blue) and a matched isotype control NBP2-27287 (orange). Cells were incubated in an antibody dilution of 1 ug/mL for 20 minutes at room temperature. The antibodies were directly conjugated to Alexa Fluor 488. 0.1 mL Log in to see 7 to 9 Days
$418.10
Details

Top referenced anti-CD147 Antibodies

  1. Human Monoclonal CD147 Primary Antibody for FACS - ABIN5500581 : Choi, Yu, Smuga-Otto, Salvagiotto, Rehrauer, Vodyanik, Thomson, Slukvin: Hematopoietic and endothelial differentiation of human induced pluripotent stem cells. in Stem cells (Dayton, Ohio) 2009 (PubMed)
    Show all 9 Pubmed References

  2. Rat (Rattus) Monoclonal CD147 Primary Antibody for CyTOF, FACS - ABIN4889984 : Fossum, Mallett, Barclay: The MRC OX-47 antigen is a member of the immunoglobulin superfamily with an unusual transmembrane sequence. in European journal of immunology 1991 (PubMed)
    Show all 6 Pubmed References

  3. Human Monoclonal CD147 Primary Antibody for FACS, IP - ABIN533486 : Tang, Nakada, Rafferty, Laraio, McCabe, Millar, Cunningham, Snyder, Bugelski, Yan: Regulation of vascular endothelial growth factor expression by EMMPRIN via the PI3K-Akt signaling pathway. in Molecular cancer research : MCR 2006 (PubMed)
    Show all 5 Pubmed References

  4. Human Monoclonal CD147 Primary Antibody for CyTOF, FACS - ABIN5500590 : Lathia, Gallagher, Myers, Li, Vasanji, McLendon, Hjelmeland, Huang, Rich: Direct in vivo evidence for tumor propagation by glioblastoma cancer stem cells. in PLoS ONE 2011 (PubMed)
    Show all 5 Pubmed References

  5. Human Monoclonal CD147 Primary Antibody for BI, IHC (fro) - ABIN2689942 : Olivier, Rybicki, Bouhassira: Differentiation of human embryonic stem cells into bipotent mesenchymal stem cells. in Stem cells (Dayton, Ohio) 2006 (PubMed)
    Show all 4 Pubmed References

  6. Mouse (Murine) Polyclonal CD147 Primary Antibody for CyTOF, FACS - ABIN4899651 : Ramo, Cashman, Kumar-Singh: Evaluation of adenovirus-delivered human CD59 as a potential therapy for AMD in a model of human membrane attack complex formation on murine RPE. in Investigative ophthalmology & visual science 2008 (PubMed)
    Show all 4 Pubmed References

  7. Human Monoclonal CD147 Primary Antibody for FACS, IHC (p) - ABIN535271 : Schmidt, Bültmann, Fischel, Gillitzer, Cullen, Walch, Jost, Ungerer, Tolley, Lindemann, Gawaz, Schömig, May: Extracellular matrix metalloproteinase inducer (CD147) is a novel receptor on platelets, activates platelets, and augments nuclear factor kappaB-dependent inflammation in monocytes. in Circulation research 2008 (PubMed)
    Show all 3 Pubmed References

  8. Human Polyclonal CD147 Primary Antibody for FACS, WB - ABIN3043762 : Lu, Lv, Kim, Ha, Kim: Expression and clinical significance of extracellular matrix metalloproteinase inducer, EMMPRIN/CD147, in human osteosarcoma. in Oncology letters 2012 (PubMed)
    Show all 3 Pubmed References

  9. Human Polyclonal CD147 Primary Antibody for WB - ABIN3043170 : Zhang, Yang, Liu, Liu, Teng, Zhang, Yin, Liu et al.: iTRAQ-coupled 2D LC/MS-MS analysis of CXCR7-transfected papillary thyroid carcinoma cells: A new insight into CXCR7 regulation of papillary thyroid carcinoma progression and identification of ... in Oncology letters 2017 (PubMed)
    Show all 3 Pubmed References

  10. Human Polyclonal CD147 Primary Antibody for FACS - ABIN5693186 : Xiao, Zhao, Shen, Liang, Chen: Overexpression of CD147 is associated with poor prognosis, tumor cell migration and ERK signaling pathway activation in hepatocellular carcinoma. in Experimental and therapeutic medicine 2017 (PubMed)
    Show all 3 Pubmed References

More Antibodies against CD147 Interaction Partners

Cow (Bovine) Basigin (Ok Blood Group) (BSG) interaction partners

  1. Data suggest that EMMPRIN derived from endometrial epithelial cells regulates expression of matrix metalloproteinases (MMP-2; MMP-14) in endometrial stromal cells; progesterone-rich conditions stimulate expression of EMMPRIN in endometrium.

  2. The selective S-nitrosylation of EMMPRIN and GOLPH3 at the Golgi apparatus in endothelial cells results from the physical proximity to eNOS-derived nitric oxide.

Human Basigin (Ok Blood Group) (BSG) interaction partners

  1. PKM2 and other key regulators of Warburg effect positively correlate with CD147 (EMMPRIN) gene expression and predict survival in multiple myeloma.

  2. In periodontitis, EMMPRIN regulates MMP-2, 9 expressions, the activation of Wnt/beta-catenin signaling pathway downregulates the EMMPRIN/MMP-2, 9 routes and the blockade of EMMPRIN attenuates Wnt/beta-catenin signaling pathway.

  3. Overexpression of EMMPRIN was associated with lymphatic metastasis and advanced stage of non-small cell lung cancer

  4. Disrupting CD147-RAP2 interaction abrogates erythrocyte invasion by Plasmodium falciparum.

  5. Results demonstrated that CD147 serves a key role in melanoma cell apoptosis, which may be mediated via IGFBP2 and the PTEN/PI3K/AKT signaling pathway. In addition, the expression of IGFBP2 and CD147 was upregulated and exhibited a positive association in melanoma clinical tissues.

  6. findings suggest that the OK/BSG expression levels on RBCs might be related to P. falciparum invasion

  7. Silencing of CD147 in endothelial cells inhibited Human cytomegalovirus entry but not entry into fibroblasts.

  8. ectopic CD147-polarized distribution on basolateral membrane promotes hepatocyte depolarization by activation of the CD147-integrin alpha5beta1-E-cadherin ubiquitination-partitioning defective 3 decrease and beta-catenin translocation signaling cascade, replenishing a molecular pathway in hepatic carcinogenesis

  9. CD147 and the beta2-adrenergic receptor form hetero-oligomeric complexes.Actinin-4 directly binds to the cytosolic tail of CD147 and governs the assembly of CD147-beta2-adrenergic receptor complexes in highly ordered clusters at bacterial adhesion sites.

  10. Plasma sCD147 levels are elevated in breast cancer patients. Soluble CD147 is also associated with tumour size, lymph node metastasis, high recurrent risk, and chemoresistance.

  11. overexpression of CD147 may promote OSF progression.

  12. these findings show that CD147 is a novel and key mediator of IL-22-induced psoriatic alterations in the epidermis and might be a therapeutic target in patients with psoriasis.

  13. Data indicate that CD147 promotes breast cancer cell proliferation, metastasis, and invasion by modulating matrix metalloproteinase 9 (MMP-9) and vascular endothelial growth factor (VEGF) expression.

  14. BSG expression is indicative of a poor prognosis in pulmonary adenocarcinoma

  15. CD147 expression was associated with clinicopathological features and biomarkers related to triple-negative breast cancer, particularly basal-like breast cancer.

  16. Characterization of the role of CD147 in the development of tumors should lead to a better understanding of the changes occurring at the molecular level during the development and progression of primary human bone cancer.

  17. Results find CD147 expression level increased in colorectal cancer (CRC) tumors and cell lines and inversely correlated with mir-485 expression. Also, CD147 is a target gene of miR485 which negatively regulates its gene expression.

  18. Our results indicate that concomitant stimulation and colocalization of galectin-3 with CD147 are associated with increased gelatinolytic activity in the actively ulcerating human cornea

  19. These findings reveal an important cytomegalovirus mechanism for evading antiviral innate immunity through its encoded microRNA US25-1-5p by targeting transmembrane glycoprotein CD147.

  20. on a major part of fibroblastic cells in encapsulating peritoneal sclerosis

Mouse (Murine) Basigin (Ok Blood Group) (BSG) interaction partners

  1. The fibroblast-specific deletion of Basigin did not influence the growth, fertility and the general condition of the mice. No obvious differences were found in the size, morphology, and histological structure of the major organs, including heart, liver, spleen, lung and kidney, between the knockout mice and the control mice. The deletion of Basigin in fibroblasts did not induce apoptosis in the tissues of the major organs

  2. ectopic CD147-polarized distribution on basolateral membrane promotes hepatocyte depolarization by activation of the CD147-integrin alpha5beta1-E-cadherin ubiquitination-partitioning defective 3 decrease and beta-catenin translocation signaling cascade, replenishing a molecular pathway in hepatic carcinogenesis

  3. CD147 deletion in hepatic stellate cells alleviated CCl4-induced liver fibrosis and inhibited HSCs activation. Overexpression of CD147 upregulated the secretion of CXCL1.

  4. A new molecular mechanism for high angiogenic capacity, whereby microglia cells release basigin via up-regulation of PI3K-AKT and IGF-1 pathway to induce angiogenesis is unveiled.

  5. EMMPRIN inhibited bFGF-induced IL-6 secretion by reducing the p65 subunit phosphorylation, it might be concluded that bFGF and EMMPRIN crosstalk in their respective signaling pathways.

  6. protein-protein interaction studies on TRAF6 and BSG to get molecular level insights of the reactions.

  7. This study has highlighted basigin as a common essential molecule for various stimuli-induced impairment of retinal vascular barrier, which can be a target for strategies to establish a curative treatment of diabetic retinopathy

  8. Deletion of N-linked glycosylation at Asn152 on CD147 significantly suppressed in situ tumor metastasis in hepatocellular carcinoma.

  9. MCT1 and Basigin variant-2, but not Basigin variant-1, are expressed within the mouse pineal gland.

  10. this study provided a new mechanistic concept that CD147 can be a target for lymphocyte lineage reprogramming.

  11. these results suggested that CD147 plays a key role in reducing extrinsic apoptosis in spermatocytes, but not spermatogonia, through modulating NFkappaB signaling pathway.

  12. results establish neuroplastin and basigin as obligatory auxiliary subunits of native Plasma Membrane Calcium Atpases and key regulators of intracellular Ca2+ concentration.

  13. Data show that caveolin-3 binds to low glycosylated extracellular matrix metalloproteinase inducer (LG-EMMPRIN) in cardiac cells and in the hearts of healthy mice.

  14. These results suggest that basigin has a functional role as a binding partner with MCT2 in testicular and epididymal spermatozoa.

  15. both caveolin-1 and EMMPRIN mRNA levels increased gradually with progression of developmental stages, and peaked at day two postnatal. The current finding suggests that both caveolin-1 and EMMPRIN take part in mouse tooth development, especially in the differentiation and organization of odontogenic tissues.

  16. knockdown of CD147 on Hepa1-6 cells resulted in significantly increased T cells chemotaxis induced by CypA both in vivo and in vitro.

  17. These findings indicate that TGF-beta1-CD147 loop plays a key role in regulating the HSC activation and combination of TGF-beta receptor inhibitor and anti-CD147 antibody might be promised to reverse fibrogenesis.

  18. Decreased CD147 expression inhibited osteoclast formation and bone resorption, inhibited RANKL-induced nuclear translocation of the nuclear factor of activated T cells NFATc1.

  19. EMMPRIN promotes tumor growth and metastasis by recruitment of bone marrow-derived cells through controlling secretion and paracrine signaling of SDF-1 and VEGF.

  20. Results indicate the crucial roles of intracellular and extracellular Bsg in the pathogenesis of cardiac hypertrophy, fibrosis, and failure.

Rabbit Basigin (Ok Blood Group) (BSG) interaction partners

  1. CD147 is required for the expression of MCT1 and MCT4 in the corneal endothelium. Silencing CD147 slows lactate efflux, resulting in stromal lactate accumulation and corneal edema.

CD147 (BSG) Antigen Profile

Protein Summary

The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with BSG

  • basigin (Ok blood group) (BSG) antibody
  • basigin (Bsg) antibody
  • basigin (Ok blood group) (Bsg) antibody
  • basigin (bsg) antibody
  • basigin (Ok blood group) S homeolog (bsg.S) antibody
  • 5A11 antibody
  • 5F7 antibody
  • AI115436 antibody
  • AI325119 antibody
  • basignin antibody
  • bsg antibody
  • CD147 antibody
  • CE9 antibody
  • EMMPRIN antibody
  • HT-7 antibody
  • HT7 antibody
  • M6 antibody
  • OK antibody
  • Ox47R antibody
  • prso03 antibody
  • RPE7 antibody
  • TCSF antibody
  • wu:fb26a05 antibody
  • wu:fo98e12 antibody

Protein level used designations for BSG

basigin , CD147 antigen , OK blood group antigen , collagenase stimulatory factor , extracellular matrix metalloproteinase inducer , leukocyte activation antigen M6 , tumor cell-derived collagenase stimulatory factor , 5A11/Basigin , HT7 antigen , basic immunoglobulin superfamily , gp 42 , membrane glycoprotein gp42 , neurothelin , gp42/basigin/OX-47/HT7 , Basigin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian) , Basignin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian) , OX-47 antigen , glycoprotein CE9 , 5A11 antigen , blood-brain barrier HT7 antigen , 5A11/Basigin-2 , cd147 , basigin (Ok blood group) S homeolog

GENE ID SPECIES
508716 Bos taurus
682 Homo sapiens
12215 Mus musculus
100009229 Oryctolagus cuniculus
100141312 Sus scrofa
25246 Rattus norvegicus
770363 Gallus gallus
476758 Canis lupus familiaris
100720467 Cavia porcellus
337692 Danio rerio
100689246 Cricetulus griseus
734661 Xenopus laevis
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