anti-Bleomycin Hydrolase (BLMH) Antibodies

Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution\; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. Additionally we are shipping BLMH Proteins (20) and BLMH Kits (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BLMH 104184 Q8R016
BLMH 287552  
BLMH 642 Q13867
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Top anti-BLMH Antibodies at antibodies-online.com

Showing 10 out of 89 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-BLMH Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: 721_B cell lysate 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: Blmh Sample Type: Mouse Stomach lysates Antibody Dilution: 1.0ug/ml 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: A549 10% SDS PAGE antibody diluted at 1:1000 100 μL 3 to 4 Days
$466.18
Details
Human Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$537.17
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Mouse Rabbit Un-conjugated IP, ELISA, WB 100 μL 14 to 16 Days
$247.82
Details
Human Rabbit Un-conjugated IP, ELISA, WB 100 μL 14 to 16 Days
$247.82
Details
Human Rabbit Biotin IHC, ELISA, WB 100 μL 15 to 18 Days
$270.00
Details
Human Rabbit Un-conjugated ICC, IHC, WB 100 μL 15 to 18 Days
$245.00
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB DAB staining on IHC-P; Samples: Mouse Testis Tissue 100 μL 13 to 16 Days
$252.00
Details

Top referenced anti-BLMH Antibodies

  1. Human Polyclonal BLMH Primary Antibody for ELISA, WB - ABIN560067 : Englert, Kliment, Ramsgaard, Milutinovic, Crum, Tobolewski, Oury: Paradoxical function for the receptor for advanced glycation end products in mouse models of pulmonary fibrosis. in International journal of clinical and experimental pathology 2011 (PubMed)
    Show all 2 Pubmed References

More Antibodies against BLMH Interaction Partners

Mouse (Murine) Bleomycin Hydrolase (BLMH) interaction partners

  1. Blmh interacts with diverse cellular processes--lipoprotein, amino acid and protein, carbohydrate, and energy metabolisms, detoxification, antioxidant defenses--that are essential for normal kidney homeostasis.

  2. Bleomycin hydrolase protects against neurodegeneration associated with elevated homocysteine thiolactone levels in hyperhomocysteinemia and Alzheimer's disease.

  3. bleomycin hydrolase functions as an MHC class I epitope-processing protease

  4. BH does not play a major role either in generating or destroying class I major histocompatibility antigen (MHC)-presented peptides that bind to the MHC in living cells. These results point to redundant functions between peptidases.

Human Bleomycin Hydrolase (BLMH) interaction partners

  1. the BLMH gene single nucleotide polymorphism A1450G (rs1050565) influences BLMH activity and late pulmonary toxicity.

  2. Ubc9 plays different roles of action in antitumor agents in chemotherapy. The process requires bleomycin hydrolase and poly(ADP-ribose) polymerase-1. The results are beneficial to deeply understanding of Ubc9 functions and for precise prediction of chemotherapy outcomes in tumors.

  3. Bleomycin hydrolase downregulation in lesional skin of adult atopic dermatitis patients is independent of filaggrin gene mutations

  4. This study findings suggest that Blmh interacts with diverse cellular processes from energy metabolism and anti-oxidative defenses to cell cycle, cytoskeleton dynamics, and synaptic plasticity essential for normal brain homeostasis.

  5. We also detected significant association between XRCC1, XRCC3, and BLHX polymorphisms and a high frequency of chromosomal damage

  6. The caspase-dependent cleavage of BLH was confirmed by cleavage of partly-purified human bleomycin hydrolase with caspase-3.

  7. BH may play an important role during the late stage of epidermal differentiation.

  8. present study suggests that our new method can detect novel genes of interest and that BLMH is a suppressor gene in HCC

  9. This first report on BLMH carrier status in Tunisia shows o association between carrying the BLMH-G genotype and Alzheimer's disease in epsilon4 negative or positive subjects.

  10. Cysteine proteases bleomycin hydrolase and cathepsin Z mediate N-terminal proteolysis and toxicity of mutant huntingtin.

  11. BH activity and expression were markedly decreased in AD lesional skin, suggesting a defect of the filaggrin degradation pathway in AD.

  12. Polymorphism is associated with neurodegenerative diseases, notably Alzheimer disease.

  13. Significant effect of BLHX variant alleles (A/G, G/G) on the chromosome damage induced by bleomycin.

  14. The homozygous variant G/G of BLMH gene SNP A1450G is associated with reduced survival and higher prevalence of early relapses in TC patients treated with bleomycin-containing chemotherapy.

BLMH Antigen Profile

Protein Summary

Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution\; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily.

Gene names and symbols associated with BLMH

  • bleomycin hydrolase (BLMH) antibody
  • Bleomycin hydrolase (pepC) antibody
  • bleomycin hydrolase (LOC5569945) antibody
  • Bleomycin hydrolase (Apre_0140) antibody
  • Bleomycin hydrolase (Apar_0899) antibody
  • Bleomycin hydrolase (Smon_1289) antibody
  • Bleomycin hydrolase (Kfla_1242) antibody
  • Bleomycin hydrolase (Snas_3912) antibody
  • bleomycin hydrolase (BLJ_1941) antibody
  • Bleomycin hydrolase (Olsu_1085) antibody
  • bleomycin hydrolase (PGTDC60_0106) antibody
  • bleomycin hydrolase (Blmh) antibody
  • bleomycin hydrolase (blmh) antibody
  • bleomycin hydrolase S homeolog (blmh.S) antibody
  • AI035728 antibody
  • BH antibody
  • BMH antibody
  • wu:fb13c01 antibody
  • zgc:66261 antibody

Protein level used designations for BLMH

Bleomycin hydrolase , bleomycin hydrolase , BLM hydrolase , BH , BMH , aminopeptidase H

GENE ID SPECIES
100072223 Equus caballus
5300178 Flavobacterium psychrophilum JIP02/86
5569945 Aedes aegypti
8396891 Anaerococcus prevotii DSM 20548
8413765 Atopobium parvulum DSM 20469
8601031 Streptobacillus moniliformis DSM 12112
8717835 Kribbella flavida DSM 17836
8885112 Stackebrandtia nassauensis DSM 44728
9190601 Bifidobacterium longum subsp. longum JDM301
9499925 Olsenella uli DSM 7084
10722336 Porphyromonas gingivalis TDC60
104184 Mus musculus
287552 Rattus norvegicus
336541 Danio rerio
734349 Xenopus laevis
395996 Gallus gallus
642 Homo sapiens
480635 Canis lupus familiaris
504483 Bos taurus
100009580 Oryctolagus cuniculus
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