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Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit (By similarity). Additionally we are shipping Block of Proliferation 1 Antibodies (49) and Block of Proliferation 1 Proteins (5) and many more products for this protein.
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The DDX27 can interact specifically with the Pes1 and Bop1 but fulfils critical function(s) for proper 3' end formation of 47S rRNA independently of the PeBoW-complex.
Block of proliferation 1 (BOP1) plays an oncogenic role in hepatocellular carcinoma by promoting epithelial-to-mesenchymal transition.
Deregulation of the BOP1 pathway contributes to chromosomal instability in colorectal tumorigenesis.
New direct Wnt/beta-catenin target gene Bop1, which induced epithelial-mesenchymal transition, cell migration and experimental metastasis of Colorectal cancer cells was identified.
Murine fibroblasts expressing Scx mRNA from an exogenous Scx mini-gene indicated that the accumulation of Bop1 intronic RNA impairs the Scx gene expression in a trans-acting manner, which resulted in the reduction of the Scx mRNA level.
inactivation of inhibits multiple steps in pre-rRNA processing and blocks cell cycle progression
Bop1 form a stable complex with a novel member, WDR12 (PeBoW complex).
Results describe the role of PeBoW-specific proteins Pes1, Bop1, and WDR12 in complex assembly and stability, nucleolar transport, and pre-ribosome association.
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit (By similarity).
Block of proliferation 1
, block of proliferation 1
, Block of proliferation 1 protein B
, ribosome biogenesis protein bop1-B
, block of proliferation 1 protein
, ribosome biogenesis protein BOP1
, ribosome biogenesis protein bop1