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BRD1 encodes a protein of unknown function. Additionally we are shipping Bromodomain Containing 1 Proteins (6) and Bromodomain Containing 1 Kits (3) and many more products for this protein.
Showing 10 out of 49 products:
Human Polyclonal BRD1 Primary Antibody for ICC, IF - ABIN4285216
Kiflemariam, Andersson, Asplund, Pontén, Sjöblom: Scalable in situ hybridization on tissue arrays for validation of novel cancer and tissue-specific biomarkers. in PLoS ONE 2012
TIMP-4 (show TIMP4 Antibodies), NT-proANP, NT-proBNP were strongest associated with PAF (show PAF Antibodies) and AHRE (show AHR Antibodies). The discriminatory performance of CHADS2-VASc for PAF (show PAF Antibodies) was increased by addition of selected biomarkers.
Structural and mechanistic insights into regulation of HBO1 (show MYST2 Antibodies) histone acetyltransferase (show HAT Antibodies) activity by BRPF2 have been presented.
Reduced BRD1 expression is associated with Schizophrenia.
Findings show that BRD1 primarily binds in close proximity to transcription start sites and regulates expression of numerous genes, many of which are involved with brain development and susceptibility to mental disorders.
The PHD (show PDC Antibodies) finger of BRPF2 can potentially bind DNA non-specifically with an evolutionarily conserved and positively charged surface.
Recognition of unmodified histone H3 (show HIST3H3 Antibodies) by the first PHD (show PDC Antibodies) finger of bromodomain-PHD finger protein 2 (show PHF2 Antibodies) provides insights into the regulation of histone acetyltransferases monocytic leukemic zinc-finger protein (MOZ (show MYST3 Antibodies)) and MOZ-related factor (MORF (show KAT6B Antibodies)).
BRD1 may have a role in schizophrenia and bipolar affective disorder
The association of BRD1 with schizophrenia in a Japanese population, was analysed.
These results suggest a general role of BRD1 in the cell and stress that the two BRD1 variants may play different roles in the etiology of psychiatric disease.
Brd1(+/-) mice exhibit relational encoding deficits, compromised working and long term memory, as well as impaired executive cognitive functioning with cognitive behaviors relying on medial prefrontal cortex being particularly affected. Akin to patients with schizophrenia, the cognitive deficits displayed by Brd1(+/)(-) mice are not global, but selective.
results demonstrate widespread gene expression alterations in the brains of Brd1 +/- mice.
BRPF2 (show BRPF1 Antibodies)-MOZ (show MYST3 Antibodies) complexes play an important role in the differentiation of embryonic stem cells via H3K14 acetylation.
Brd1-mediated Hbo1 (show MYST2 Antibodies) activity is crucial for efficient activation of CD8 (show CD8A Antibodies) expression via acetylation at H3K14, which serves as an epigenetic mark that promotes the recruitment of transcription machinery to the CD8 (show CD8A Antibodies) enhancers.
The Hbo1 (show MYST2 Antibodies)-Brd1 complex is the major H3K14 HAT (show HAT Antibodies) required for transcriptional activation of erythroid developmental regulator (show GIPC1 Antibodies) genes.
This gene encodes a protein of unknown function. The protein contains a bromodomain, a sequence motif often found in transcriptional coactivators, and localizes to the nucleus in testis and several other cell types.
bromodomain-containing protein 1
, bromodomain containing 1
, bromodomain containing protein 1
, bromodomain-containing protein 1-like
, BR140-like protein
, bromodomain and PHD finger-containing protein 2