anti-C-Type Lectin Domain Family 10, Member A (CLEC10A) Antibodies

CLEC10A encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Additionally we are shipping CLEC10A Proteins (23) and CLEC10A Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CLEC10A 10462 Q8IUN9
CLEC10A 17312 P49300
CLEC10A 64195  
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Top anti-CLEC10A Antibodies at antibodies-online.com

Showing 10 out of 138 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, WB CLEC10A Antibody (N-term) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. CLEC10A Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35µg/lane).This demonstrates the CLEC10A antibody detected the CLEC10A protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Mouse Rat Un-conjugated ICC, FACS, IHC (fro), IF, IHC Flow Cytometry: CLEC10A/CD301 Antibody (ER-MP23)  - A surface stain was performed on RAW 246.7 cells with CLEC10A/CD301 antibody (ER-MP23) 4AF647 (blue) and a matched isotype control (orange). Cells were incubated in an antibody dilution of 2 ug/mL for 20 minutes at room temperature. Both antibodies were conjugated to Alexa Fluor 647. Immunohistochemistry: CLEC10A/CD301 Antibody (ER-MP23)  - Staining of a mouse lymph node with Rat anti Mouse CD301 antibody, clone ER-MP23 followed by horseradish peroxidase conjugated Goat anti Rat IgG antibody (STAR72). Medium power 0.125 mg Log in to see 7 to 9 Days
$446.35
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Rat Testis Tissue. 100 μg Log in to see 13 to 16 Days
$332.00
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Mouse Lung Tissue; Lane2: Mouse Testis Tissue; Lane3: Mouse Cerebellum Tissue; Lane4: Rat Testis Tissue. 100 μg Log in to see 13 to 16 Days
$342.00
Details
Human Rabbit Un-conjugated FACS, WB CLEC10A Antibody (N-term)  western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the CLEC10A antibody detected the CLEC10A protein (arrow). CLEC10A Antibody (N-term)  flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Mouse Rat Biotin FACS   0.1 mg Log in to see 6 to 8 Days
$852.50
Details
Mouse Rat Un-conjugated Func, FACS, IHC (fro)   0.5 mg Log in to see 6 to 8 Days
$731.50
Details
Human Mouse Alexa Fluor 488 FACS Detection of CLEC10A/CD301 in Human Dendritic Cells by Flow Cytometry. Human immature dendritic cells were stained with Mouse Anti-Human CLEC10A/CD301 Alexa Fluor 488-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$342.39
Details
Human Mouse Un-conjugated CyTOF, FACS Detection of CLEC10A in Immature Human Dendritic Cells by Flow Cytometry. 100 μg Log in to see 8 to 9 Days
$297.19
Details
Human Goat Un-conjugated CyTOF, FACS, WB Detection of CLEC10A in Human Dendritic Cells by Flow Cytometry. Human immature dendritic cells were stained with Goat Anti-Human/Mouse CLEC10A/CD301 Antigen Affinity-purified Polyclonal Antibody. Detection of Human CLEC10A/CD301 by Western Blot. Western blot shows lysates of human immature dendritic cells and human mature dendritic cells. PVDF membrane was probed with 1 ug/mL of Goat Anti-Human/Mouse CLEC10A/CD301 Antigen Affinity-purified Polyclonal Antibody. This experiment was conducted under reducing conditions. 100 μg Log in to see 8 to 9 Days
$300.58
Details

Top referenced anti-CLEC10A Antibodies

  1. Mouse (Murine) Monoclonal CLEC10A Primary Antibody for FACS - ABIN2479886 : Kaslow, Rosse, Zeller, Nagy, Deustch: Phenothiazine-induced lupus anticoagulant. in The Journal of clinical psychiatry 1992 (PubMed)
    Show all 4 Pubmed References

  2. Mouse (Murine) Monoclonal CLEC10A Primary Antibody for FACS - ABIN2479888 : Leenen, de Bruijn, Voerman, Campbell, van Ewijk: Markers of mouse macrophage development detected by monoclonal antibodies. in Journal of immunological methods 1994 (PubMed)
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  3. Mouse (Murine) Monoclonal CLEC10A Primary Antibody for IHC (fro), FACS - ABIN2479884 : Abadie, Badell, Douillard, Ensergueix, Leenen, Tanguy, Fiette, Saeland, Gicquel, Winter: Neutrophils rapidly migrate via lymphatics after Mycobacterium bovis BCG intradermal vaccination and shuttle live bacilli to the draining lymph nodes. in Blood 2005 (PubMed)
    Show all 4 Pubmed References

  4. Mouse (Murine) Monoclonal CLEC10A Primary Antibody for FACS - ABIN2479890 : Geutskens, Otonkoski, Pulkkinen, Drexhage, Leenen: Macrophages in the murine pancreas and their involvement in fetal endocrine development in vitro. in Journal of leukocyte biology 2005 (PubMed)
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  5. Human Monoclonal CLEC10A Primary Antibody for IHC (fro), FACS - ABIN786558 : Debeer, Le Luduec, Kaiserlian, Laurent, Nicolas, Dubois, Kanitakis: Comparative histology and immunohistochemistry of porcine versus human skin. in European journal of dermatology : EJD 2013 (PubMed)
    Show all 2 Pubmed References

  6. Human Monoclonal CLEC10A Primary Antibody for IHC (fro), FACS - ABIN786559 : Napoletano, Zizzari, Rughetti, Rahimi, Irimura, Clausen, Wandall, Belleudi, Bellati, Pierelli, Frati, Nuti: Targeting of macrophage galactose-type C-type lectin (MGL) induces DC signaling and activation. in European journal of immunology 2012 (PubMed)
    Show all 2 Pubmed References

  7. Mouse (Murine) Polyclonal CLEC10A Primary Antibody for CyTOF, FACS - ABIN4900425 : Shaul, Bennett, Strissel, Greenberg, Obin: Dynamic, M2-like remodeling phenotypes of CD11c+ adipose tissue macrophages during high-fat diet--induced obesity in mice. in Diabetes 2010 (PubMed)

More Antibodies against CLEC10A Interaction Partners

Human C-Type Lectin Domain Family 10, Member A (CLEC10A) interaction partners

  1. this paper shows that key gene of intermediate proinflammatory monocytes, such as CLEC10A, is expressed three- to fourfold more in juvenile idiopathic arthritis-enthesitis-related arthritis

  2. BRAF(V600E) mutation induces MGL ligand expression, thereby providing a direct link between oncogenic transformation and aberrant expression of immunosuppressive glycans in colorectal neoplasms.

  3. These results indicate a role of MGL as an immunomodulator within the tumour microenvironment interfering with Treg functions, suggesting its possible use in the design of anticancer vaccines.

  4. expression of GalNAc moieties mirrors the T cell activation status, and thus only highly stimulated T cells are prone to the suppressive action of MGL.

  5. MGL triggering synergized with TLR2-induced pathways, leading to elevated IL-10 mRNA levels & enhanced TNF-alpha mRNA stability. It promoted phosphorylation of the ERK & CREB, fine-tuning the DC maturation phenotype.

  6. Described is the use of recombinant CLEC10A (CD301), a human glycoreceptor of the C-type lectin family, for the detection of ligands in sections from formalin-fixed, paraffin-embedded normal and cancerous mammary tissues.

  7. MGL engagement improved DC performance as antigen-presenting cells, promoting the upregulation of maturation markers, a decrease in phagocytosis, an enhancement of motility, and most importantly an increase in antigen-specific CD8(+) T-cell activation.

Mouse (Murine) C-Type Lectin Domain Family 10, Member A (CLEC10A) interaction partners

  1. Macrophage Galactose-Type Lectin-1 Deficiency Is Associated with Increased Neutrophilia and Hyperinflammation in Gram-Negative Pneumonia

  2. Mgl1-deficient mice displayed accelerated colonic propulsion and were hypersensitive to mu receptor-mediated inhibition of colonic motility.

  3. MGL1 is involved in T. crassiceps recognition and subsequent innate immune activation and resistance.

  4. The MGL1 functions as an attachment and entry receptor for influenza A virus.

  5. Syk was involved in the CLR-mediated activation of mast cells by BP

  6. Hoxc8 downregulates Mgl1 tumor suppressor gene expression and reduces its concomitant function on cell adhesion.

  7. The authors conclude that lectin-mediated interactions of influenza virus with the MMR or the MGL are required for the endocytic uptake of the virus into macrophages.

  8. mMGL1 preferentially binds Lewis X-conjugated soluble polyacrylamides

  9. Generation of mice deficient for macrophage galactose- and N-acetylgalactosamine-specific lectin: limited role in lymphoid and erythroid homeostasis and evidence for multiple lectins.

  10. sialoadhesin acts as an endogenous counter-receptor for MGL1

  11. The mMGL1 protein is induced in diverse populations of aaMF, including peritoneal macrophages elicited during infection with the protozoan Trypanosoma brucei brucei or the Helminth Taenia crassiceps and alveolar macrophages elicited.

  12. MGL1 expressed on a specific subpopulation of macrophages that secrete IL-1alpha was proposed to regulate specific cellular interactions crucial to granulation tissue formation

  13. MGL1/CD301a is involved in the clearance of apoptotic cells

  14. analysis of protein-protein interactions in the Mgl-1 oncoprotein

  15. MGL1 mutants of Ala89Arg and Ala89Arg/Pro115Arg showed beta-GalNAc bindings.

  16. Carbohydrate binding mechanism of the macrophage galactose-type C-type lectin 1 revealed by saturation transfer experiments.(

  17. MGL1/CD301a plays a protective role against colitis

  18. MGL1 as a novel regulator of inflammatory monocyte trafficking to adipose tissue in response to diet-induced obesity.

CLEC10A Antigen Profile

Protein Summary

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene names and symbols associated with CLEC10A

  • C-type lectin domain family 10 member A (LOC607405) antibody
  • C-type lectin domain containing 10A (CLEC10A) antibody
  • C-type lectin domain family 10, member A (Clec10a) antibody
  • C-type lectin domain containing 10A (Clec10a) antibody
  • CD301 antibody
  • CD301a antibody
  • CLEC10A antibody
  • CLECSF13 antibody
  • CLECSF14 antibody
  • HML antibody
  • HML2 antibody
  • M-ASGP-BP-1 antibody
  • Mgl antibody
  • Mgl1 antibody
  • Mgll antibody

Protein level used designations for CLEC10A

C-type lectin domain family 10, member A , C-type lectin, superfamily member 14 , C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 13 (macrophage-derived) , C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 14 (macrophage-derived) , C-type lectin domain family 10 member A , macrophage lectin 2 (calcium dependent) , macrophage asialoglycoprotein-binding protein 1 , macrophage galactose N-acetyl-galactosamine specific lectin 1 , Gal/GalNAc-specific lectin , M-ASGP-BP , M-ASGP-BP-1 , MMGL , macrophage galactose/N-acetylgalactosamine-specific lectin , monoglyceride lipase

GENE ID SPECIES
607405 Canis lupus familiaris
748824 Pan troglodytes
10462 Homo sapiens
17312 Mus musculus
64195 Rattus norvegicus
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