anti-C-Type Lectin Domain Family 4, Member M Antibodies

CLEC4M encodes a transmembrane receptor and is often referred to as L-SIGN because of its expression in the endothelial cells of the lymph nodes and liver.

Data Quality
  • 20
Type
  • 50
    Primary antibodies
Antigen
  • 50
Reactivity
  • 50
  • 14
  • 12
  • 4
  • 2
Application
  • 31
  • 16
  • 14
  • 7
  • 6
Host
  • 43
  • 7
Clonality
  • 42
  • 7
  • 1
Clone
  • 4
  • 2
  • 1
Binding Specificity
  • 5
  • 4
  • 4
  • 4
  • 2
Conjugate
  • 33
  • 3
  • 2
  • 2
  • 2
Isotype
  • 16
  • 4
  • 2
  • 2
  • 1
Protein Type
  • 4
Format
  • 19
  • 10
Suggested next Filters
50 Products
ReactivityHuman
Application IHC, WB
Order details Cat. No. ABIN630277
$421.86
100 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN634662
$517.86
50 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN634663
$517.86
50 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN928002
$517.86
50 μg
Plus shipping costs $45.00
Delivery in 9 to 11 Business Days
ReactivityHuman, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Zebrafish (Danio rerio)
Application WB
Order details Cat. No. ABIN2775394
$229.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application IHC (p), WB
Order details Cat. No. ABIN5575587
$356.00
100 μL
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN564490
$440.00
100 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman, Monkey
Application IHC, IHC (p), WB
Order details Cat. No. ABIN203419
$493.17
100 μL
Plus shipping costs $45.00
Delivery in 11 to 14 Business Days
ReactivityHuman, Mouse (Murine), Rat (Rattus)
Application ELISA, IHC (p), WB
Order details Cat. No. ABIN4901195
$369.83
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
Mouse, Monoclonal (16E7), IgG1, kappa, Recombinant Antibody
ReactivityHuman
Application FACS, IHC
Order details Cat. No. ABIN5668173
$435.60
200 μg
Plus shipping costs $45.00
Delivery in 7 to 11 Business Days
Rabbit, Chimeric (16E7), IgG, kappa, Recombinant Antibody
ReactivityHuman
Application FACS, IHC
Order details Cat. No. ABIN5668174
$435.60
200 μg
Plus shipping costs $45.00
Delivery in 7 to 11 Business Days
ReactivityHuman, Pig (Porcine)
Application WB
Order details Cat. No. ABIN2775392
$229.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman, Pig (Porcine)
Application IHC, WB
Order details Cat. No. ABIN2775393
$229.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHorse (Equine), Human, Pig (Porcine)
Application WB
Order details Cat. No. ABIN2775566
$229.00
100 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application ICC, IHC, WB
Order details Cat. No. ABIN1858422
$232.00
Plus shipping costs $45.00
Delivery in 13 to 16 Business Days
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C-Type Lectin Domain Family 4, Member M (CLEC4M) Antigen Profile

Protein Summary

This gene encodes a transmembrane receptor and is often referred to as L-SIGN because of its expression in the endothelial cells of the lymph nodes and liver. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses, with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are common and have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 30835\; often referred to as DC-SIGN or CD209). DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants.

Gene names and symbols associated with CLEC4M

  • C-type lectin domain family 4 member M (CLEC4M) antibody
  • CD209B antibody
  • CD209L antibody
  • CD299 antibody
  • DC-SIGN2 antibody
  • DC-SIGNR antibody
  • DCSIGNR antibody
  • HP10347 antibody
  • L-SIGN antibody
  • LSIGN antibody

Protein level used designations for CLEC4M

C-type lectin domain family 4 member M , CD209 antigen-like protein 1 , CD299 antigen , DC-SIGN-related protein , dendritic cell-specific ICAM-3-grabbing non-integrin 2 , liver/lymph node-specific ICAM-3 grabbing non-integrin , liver/lymph node-specific ICAM-3-grabbing non-integrin , mannose binding C-type lectin DC-SIGNR , CD209b antigen

GENE ID SPECIES
10332 Homo sapiens
455661 Pan troglodytes