C-terminal Binding Protein 2 (CTBP2) ELISA Kits

CTBP2 produces alternative transcripts encoding two distinct proteins. Additionally we are shipping CTBP2 Antibodies (90) and CTBP2 Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CTBP2 1488 P56545
CTBP2 13017 P56546
CTBP2 81717 Q9EQH5
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Top CTBP2 ELISA Kits at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human 0.125 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests 13 to 16 Days
  96 Tests 15 to 18 Days
  96 Tests 15 to 18 Days
  96 Tests 15 to 18 Days

More ELISA Kits for CTBP2 Interaction Partners

Human C-terminal Binding Protein 2 (CTBP2) interaction partners

  1. The results represent a conserved mechanism, by which CtBP2 serves as a NADH-dependent repressor of the p300-Runx2 transcriptional complex and thus affects bone formation.

  2. CtBP2 plays a crucial role in non-small cell lung cancer progression and cis-diamminedichloroplatinum sensitivity

  3. CtBP promotes metastasis of breast cancer through repressing cholesterol and activating TGF-beta signaling

  4. Here, multi-angle light scattering (MALS) data established the NAD(+)- and NADH-dependent assembly of CtBP1 and CtBP2 into tetramers.

  5. HBV may be involved in the occurrence and development of hepatocellular carcinoma by upregulating CtBP2 expression.

  6. the present study indicated that CtBP2 reduced the susceptibility of ECA109 cells to cisplatin by regulating the expression of apoptosis-related proteins, suggesting that it may be a promising therapeutic target in esophageal squamous cell carcinoma in the future.

  7. High CTBP2 expression is associated with prostate cancer.

  8. Overall, our findings reveal that CtBP1/2 is essential to promote to human glioma cell growth through maintaining the DNA stability regulated by the MRN/ATR/Chk1/CDK2/HIF-1alpha signaling pathway.

  9. Results indicated that CTBP2 was direct target of miR-338-5p in glioma cells. CTBP2 silencing can rescued the phenotype changes induced by miR-338-5p inhibitor on cell proliferation and invasion in glioma.

  10. this study shows that CtBP2 overexpression promotes tumor cell proliferation and invasion in gastric cancer and is associated with poor prognosis

  11. these findings provide insight into the role CtBP2 plays in promoting proliferation and migration in breast cancer by the inhibition of p16INK4A.

  12. Pinin and CtBP1 and CtBP2 are oncotargets that closely interact with each other to regulate transcription and pre-mRNA alternative splicing and promote cell adhesion and other epithelial characteristics of ovarian cancer cells.

  13. CtBP2 ameliorated palmitic acid-induced insulin resistance via ROS-dependent JNK pathway.

  14. CtBP2 is a druggable transforming oncoprotein critical for the evolution of neoplasia driven by Apc mutation.

  15. CtBP2 may be a potential target to suppress tumorigenesis in neuroblastoma

  16. This Gene-based tests suggest evidence of association with related genes, ZEB2, RND3, MCTP1, CTBP2, and beta EEG

  17. Our results indicated that CCNH/CDK7-CtBP2 axis may augment ESCC cell migration, and targeting the interaction of both may provide a novel therapeutic target of esophageal squamous cell carcinoma .

  18. Releasing the key adipogenic regulator C/EBPalpha from CtBP2 binding.

  19. Enhanced CtBP2expression promoted HCC xenograft growth and induced EMT.

  20. results show how CtBP2 contributes to prostate cancer progression by modulating AR and oncogenic signaling

Mouse (Murine) C-terminal Binding Protein 2 (CTBP2) interaction partners

  1. VGLL4 acted as an adaptor protein that enhanced the interaction between TEAD4 and CtBP2, and this TEAD4-VGLL4-CtBP2 ternary complex dynamically existed at the early stage of adipogenesis.

  2. The authors postulate that RIBEYE disruption is partially compensated by several small active zone organization at each synaptic contact between inner hair cells and spiral ganglion neurons.

  3. These findings suggest a suppressive function for Ctbp2 in reducing the protein level of beta-catenin, along with priming its position on core pluripotency genes to hinder beta-catenin deposition, which is central to commitment to the appropriate lineage.

  4. studies revealed a new epigenetic pathway in the control of IL-2 production in systemic lupus erythematosus whereby low levels of miR-200a-3p accumulate the binding of the ZEB1-CtBP2 complex to the IL-2 promoter and suppress IL-2 production

  5. Our results show that RIBEYE is essential for synaptic ribbons as such, and may organize presynaptic nano-domains that position release-ready synaptic vesicles adjacent to Ca(2+) channels

  6. Ctbp2 preoccupies regions in active genes with the NuRD complex in undifferentiated ESCs that are directed toward H3K27me3 by PRC2 to induce stable silencing, which is pivotal for natural lineage commitment.

  7. Phosphorylation of KLF3 and CtBP2 by HIPK2 strengthens the interaction between these two factors and increases transcriptional repression by KLF3.

  8. propose that Zscan4 may regulate gene transcription in mouse ES cells through interaction with LSD1 and CtBP2

  9. RIBEYE(B) interacts with ArfGAP3 in vivo and in vitro.

  10. CTBP2 is indispensable to create a chromatin environment conducive for RAR/RXR-mediated transcription by recruiting the histone acetyltransferase p300.

  11. Study demonstrates differential regional and subcellular expression patterns for the two CtBP family members in brain and reveals a previously unknown synaptic localization for CtBP2 in particular brain regions.

  12. Ctbp2 has a role in maintaining a balance in decisions to self-renewal and differentiate in embryonic stem cells and mesodermal progenitors

  13. Mice harboring various combinations of Ctbp1 and Ctbp2 mutant alleles exhibit dosage-sensitive defects in a wide range of developmental processes

  14. The CtBP2 co-repressor function is regulated by an NADH-dependent effect on CtBP2 dimerization.

  15. calsenilin and CtBP2 are present in synaptic vesicles and can interact in vivo

  16. These results identify a new CtBP interaction motif and establish ZNF217 as a transcriptional repressor protein that functions, at least in part, by associating with CtBP.

  17. These results demonstrate that the PXDLS binding cleft is functionally important but suggest that it is primarily required for localization of the CtBP2 complex to promoter-bound transcription factors.

  18. analysis of the CtBP2 corepressor complex induced by E1A and modulation of E1A transcriptional activity by CtBP2

  19. E1A may gain access to cellular promoters through conservved sequence-dependent interaction with CtBP2.

  20. The regulated docking of the CtBP proteins on PRDM16 controls the brown and white fat-selective gene programs.

Zebrafish C-terminal Binding Protein 2 (CTBP2) interaction partners

  1. In photoreceptor cells, RIBEYE and RIM2 are expressed along the synaptic ribbon.

Xenopus laevis C-terminal Binding Protein 2 (CTBP2) interaction partners

  1. Tcf-3 functions as a transcriptional regulator in the canonical Wnt signaling cascade and can repress or activate downstream target genes. The tcf-3 promoter was analyzed during early development of Xenopus.

  2. Together, these results demonstrate that signaling through Tcf and Vent binding sites regulates transcription of geminin in prospective neurectoderm during gastrulation

  3. Here, we discuss the cytoplasmic roles of the CtBPs and the possible mechanisms that enable them to switch between cell compartments and multiple functions.

CTBP2 Antigen Profile

Antigen Summary

This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3\; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10.

Gene names and symbols associated with CTBP2

  • C-terminal binding protein 2 (ctbp2) antibody
  • C-terminal-binding protein 2 (LOC100398309) antibody
  • C-terminal binding protein 2 (CTBP2) antibody
  • C-terminal binding protein 2 (Ctbp2) antibody
  • C-terminal binding protein 2a (ctbp2a) antibody
  • C-terminal binding protein 2 S homeolog (ctbp2.S) antibody
  • AA407280 antibody
  • ctbp antibody
  • ctbp-b antibody
  • D7Ertd45e antibody
  • fe05b01 antibody
  • Gtrgeo6 antibody
  • Ribeye antibody
  • wu:fb96g03 antibody
  • wu:fe05b01 antibody
  • wu:fk19e02 antibody
  • xctbp antibody

Protein level used designations for CTBP2

C-terminal binding protein 2 , C-terminal-binding protein 2-like , C-terminal-binding protein 2 , ribeye , gene trap ROSA b-geo 6 , ribeye a , C-terminal-binding protein B , TCF-3 corepressor CtBP , Tcf-3 co-repressor CtBP , XCtBP

493558 Xenopus (Silurana) tropicalis
100398309 Callithrix jacchus
423958 Gallus gallus
1488 Homo sapiens
100684514 Canis lupus familiaris
281730 Bos taurus
13017 Mus musculus
81717 Rattus norvegicus
65230 Danio rerio
398147 Xenopus laevis
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