CCAAT/enhancer Binding Protein (C/EBP), delta Proteins (CEBPD)

The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. Additionally we are shipping CEBPD Antibodies (63) and CEBPD Kits (17) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CEBPD 12609 Q00322
CEBPD 1052 P49716
Rat CEBPD CEBPD 25695 Q03484
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Top CEBPD Proteins at antibodies-online.com

Showing 6 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
$6,749.58
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
$6,749.58
Details
Escherichia coli (E. coli) Human Un-conjugated SDS-PAGE analysis of Human C/EBP delta Protein. 100 μg 11 to 18 Days
$668.03
Details
Escherichia coli (E. coli) Mouse Un-conjugated SDS-PAGE analysis of Mouse C/EBP delta Protein. 100 μg 11 to 18 Days
$668.03
Details
Yeast Sheep His tag   1 mg 60 to 71 Days
$2,652.83
Details
Yeast Cow His tag   1 mg 60 to 71 Days
$2,656.50
Details

CEBPD Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
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Human ,
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More Proteins for CCAAT/enhancer Binding Protein (C/EBP), delta (CEBPD) Interaction Partners

Mouse (Murine) CCAAT/enhancer Binding Protein (C/EBP), delta (CEBPD) interaction partners

  1. These results suggest that Cebpd may protect from ionizing radiation-induced neurocognitive dysfunction by suppressing oxidative stress in aged mice.

  2. we found that ROS formation and expression of p47(phox) and p67(phox), subunits of NADPH oxidase, were increased in AppTg mice but attenuated in AppTg/Cebpd(-/-) mice. Cebpd can up-regulate p47(phox) and p67(phox) transcription via a direct binding on their promoters, which results in an increase in intracellular oxidative stress

  3. tudy underscores how CEBPD functions at the junction of inflammation and lipid accumulation in M1 macrophages

  4. astrocytic C/EBPdelta is integral to the inflammatory cascades leading to glial scar formation after spinal cord injury.

  5. These findings demonstrate a critical function for the astrocytic CEBPD, and point to miR-135a antagonist as an attractive therapeutic target for the treatment of Alzheimer's disease.

  6. This study demonstrates a novel role for CEBPd in protection from basal as well as radiation-induced oxidative stress and mitochondrial dysfunction thus promoting post-radiation survival.

  7. Results show that C/EBPbeta and C/EBPdelta actively regulate the promotor region of both splicing variants Ppargamma1sv and Ppargamma2 in mouse adipocytes.

  8. C/EBPdelta facilitates bacterial dissemination to the brain and enhances the immune response in the blood compartment. This study suggests that C/EBPdelta plays a detrimental role during the initial development of blood-borne brain infection.

  9. Taken together, these results suggested that alpha1B-adrenoceptor signaling is required for bone formation and regulated cellular proliferation through a mechanism relevant to the up-regulation of CCAAT/enhancer-binding protein delta in osteoblasts and, thus, provide new evidence for the physiological importance of alpha1B-adrenoceptor signalling in bone homeostasis

  10. The C/EBPdelta in the brain drives the inflammatory response and contributes to bacterial dissemination during pneumococcal meningitis. C/EBPdelta does, however, not affect clinical parameters of the disease and does not confer a survival benefit.

  11. CEBPA, CEBPB and CEBPD regulate proliferation and differentiation of chondrocytes.

  12. SOCS3 is an inflammatory enhancer in IgG immune complex-treated macrophages by increasing C/EBPD activity.

  13. It mediates PGE2-induced angiogenesis in Alzheimer's disease.

  14. This study provides the first evidence that ZNF179, PLZF, IGFBP3, and BIK contributed to the novel CEBPD-induced antiapoptotic feature of astrocytes.

  15. a novel biological function for C/EBPdelta in promoting the response to radiation-induced DNA-damage and in protecting hematopoietic and intestinal tissues from radiation-induced injury

  16. Studied role of C/EBPdelta in the development of renal tubulointerstitial fibrosis by subjecting 8- to 12-week-old C/EBPdelta-deficient mice and age- and sex-matched wild-type controls to the unilateral ureteral obstruction model.

  17. C/EBP delta is a mediator of the pathway from p-Stat3 to myostatin because its knockout of C/EBP delta inhibits myostatin expression and suppresses muscle wasting.

  18. CEBPbeta and CEBPdelta transcription factors are inhibited by Hsp70 treatment, and their inhibition occurs via the TLR2-ERK-STAT3-IL-10 pathway in BMDCs, mediating the anti-inflammatory effects of Hsp70.

  19. Isoniazid suppresses antioxidant response element activity and expression of C/EBPbeta and C/EBPdelta during early stage of adipogenesis.

  20. data show that C/EBPdelta is not an important factor in host defense against urinary tract infection

Human CCAAT/enhancer Binding Protein (C/EBP), delta (CEBPD) interaction partners

  1. MAIT cells selectively expressed CCAAT/enhancer-binding protein delta (C/EBPdelta). Knockdown of C/EBPdelta diminished expression of FUT7, ST3GAL4 and CCR6, decreasing MAIT cell rolling and arrest, and consequently the cells' ability to cross an endothelial monolayer in vitro and extravasate in mice.

  2. gemcabene decreases CRP by C/EBP-delta and NF-kappaB-mediated transcriptional mechanism and suppresses IL-6 and IL-1beta-induced CRP production.

  3. tudy underscores how CEBPD functions at the junction of inflammation and lipid accumulation in M1 macrophages

  4. the EGFR/STAT3 pathway contributed to CDDP-induced CEBPD expression in UCUB cells. Gefitinib and S3I-201 treatment significantly reduced the expression of CEBPD and enhanced the sensitivity of CDDP-resistant UCUB cells to CDDP and paclitaxel

  5. These findings demonstrate a critical function for the astrocytic CEBPD, and point to miR-135a antagonist as an attractive therapeutic target for the treatment of Alzheimer's disease.

  6. These findings identify a molecular mechanism by which ERalpha signaling reduces the aggressiveness of cancer cells, and demonstrate that C/EBPdelta can have different functions in different types of cancer.

  7. CREB overexpression increased CCAAT-enhancer-binding protein-delta (C/EBPdelta) levels to cause myeloid differentiation arrest, and the silencing of CREB-C/EBPdelta axis restored myeloid terminal differentiation

  8. Data suggest that proinflammatory cytokine interleukin-1beta (IL1B) up-regulates hepcidin expression in hepatocytes; inflammation induces IL1B production in Kupffer cells and hepatocytes; IL1B up-regulates CEBPD (CCAAT/enhancer binding protein delta) expression in hepatocytes; up-regulation of CEBPD expression up-regulates hepcidin transcription.

  9. the C/EBPD binding site is required for RU486-mediated activation of the CHOP promoter.

  10. Results suggest that CCAAT/enhancer binding protein delta (CEBPD) could be a useful diagnostic marker and therapeutic target in hepatocellular carcinoma (HCC).

  11. CEBPD amplification and overexpression is associated with urothelial carcinoma.

  12. Knock-down of C/EBPdelta expression in pericytes following immune stimulation increased chemokine and adhesion molecule expression.

  13. We have discovered the CEBPD-hypoxia-inducible factor-1 (HIF-1) pathway as a new HIF-1-regulating fundamental mechanism in tubular epithelial cells for the cellular protection against kidney injury.

  14. Authors found that CK2 bound to C/EBPdelta, which might help to target CK2 to the transcriptional machinery where it can phosphorylate other transcription factors or co-activators.

  15. Data indicate that dysfunction of the Rho-associated kinase 2 (Rock2)-p-GSK3beta/beta-catenin-CCAAT/enhancer-binding protein delta (CEBPD) regulatory circuitry may contribute to the tumorigenic characteristic of hepatocellular carcinoma (HCC).

  16. GSK3beta-mediated CEBPD phosphorylation in astrocytes plays an important role in the activation of microglia.

  17. Isoniazid suppresses antioxidant response element activity and expression of C/EBPbeta and C/EBPdelta during early stage of adipogenesis.

  18. the inflammatory PGE-HuR-C/EBPdelta axis in macrophages promotes tumor progression by preventing the phagocytosis of tumor cells and inducing immunosuppressive cytokine production.

  19. CEBPD inhibits FBXW7 expression and augments HIF-1 alpha expression and activity under hypoxia

  20. CEBPD supports inflammatory signaling through activation of the TLR4 gene; and is downregulated by FBXW7 alpha following phosphorylation by GSK-3 beta.

Cow (Bovine) CCAAT/enhancer Binding Protein (C/EBP), delta (CEBPD) interaction partners

  1. Elevated C/EBPdelta can induce the adipogenesis in the fibroblasts of cattle.

  2. chromosome mapping of this gene to BTA14q15-17

Xenopus laevis CCAAT/enhancer Binding Protein (C/EBP), delta (CEBPD) interaction partners

  1. Xenopus C/EBP delta plays a role in apoptotic cell death of larval-type epithelium during the stomach remodeling.

CEBPD Protein Profile

Protein Summary

The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages. The cytogenetic location of this locus has been reported as both 8p11 and 8q11.

Gene names and symbols associated with CEBPD

  • CCAAT/enhancer binding protein (C/EBP), delta (Cebpd)
  • CCAAT/enhancer binding protein delta (CEBPD)
  • CCAAT/enhancer binding protein delta (Cebpd)
  • CCAAT/enhancer binding protein delta L homeolog (cebpd.L)
  • CCAAT/enhancer binding protein delta S homeolog (cebpd.S)
  • CCAAT/enhancer binding protein delta (cebpd)
  • CCAAT/enhancer binding protein (C/EBP), delta (cebpd)
  • CCAAT/enhancer binding protein (C/EBP), delta (CEBPD)
  • c/ebp-delta protein
  • c/ebpd protein
  • cebpd protein
  • celf protein
  • crp3 protein
  • LOC398729 protein
  • LOC398730 protein
  • MGC114740 protein
  • nf-il6-beta protein
  • wu:fa99c04 protein
  • wu:fb61h03 protein

Protein level used designations for CEBPD

CCAAT/enhancer-binding protein delta , c/EBP delta , c/EBP-related protein 3 , nuclear factor NF-IL6-beta , C/EBPdelta , transcription factor CELF , C/EBP-delta , CCAAT/enhancer binding protein delta , binding protein (C/EBP), delta , CCAAT-enhancer binding protein delta , X. C/EBP delta-2 , X. C/EBP delta-1 , C/EBP delta , cebpd, CCAAT/enhancer binding protein (C/EBP), delta , CCAAT/enhancer binding protein (C/EBP), delta

GENE ID SPECIES
12609 Mus musculus
1052 Homo sapiens
25695 Rattus norvegicus
281678 Bos taurus
398729 Xenopus laevis
398730 Xenopus laevis
594973 Xenopus (Silurana) tropicalis
140817 Danio rerio
606783 Canis lupus familiaris
100050784 Equus caballus
100196464 Salmo salar
100301812 Oncorhynchus mykiss
464163 Pan troglodytes
100153946 Sus scrofa
101104916 Ovis aries
103348009 Oryctolagus cuniculus
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