CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) ELISA Kits

CTCF is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse CTCF CTCF 13018 Q61164
Anti-Human CTCF CTCF 10664 P49711
Anti-Rat CTCF CTCF 83726 Q9R1D1
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Top CTCF ELISA Kits at antibodies-online.com

Showing 4 out of 9 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 6.25 pg/mL 25-1600 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Mouse 78-5000 pg/mL   96 Tests Log in to see 2 to 3 Days
$713.90
Details
Rat
  96 Tests Log in to see 15 to 18 Days
$875.60
Details
Chicken
  96 Tests Log in to see 15 to 18 Days
$1,095.60
Details

More ELISA Kits for CTCF Interaction Partners

Zebrafish CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) interaction partners

  1. We propose that cohesin and CTCF have distinct functions in the regulation of runx1 (show RUNX1 ELISA Kits) during zebrafish embryogenesis.

  2. Data conclude that CTCF modulates MRF functional interactions in the orchestration of myogenesis.

Mouse (Murine) CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) interaction partners

  1. CCCTC-binding factor CTCF supports the homeostatic maintenance of hematopoietic stem cell (HSCs) pools by sustaining HSC quiescence in a reactive oxygen species ROS (show ROS1 ELISA Kits)-dependent manner.

  2. Authors show that mice devoid of an inducible CTCF binding element, located in the alpha constant gene, display a marked isotype-specific increase of GL transcription in developing and resting splenic B cells and altered CSR in activated B cells.

  3. The study provides evidence that CTCF regulates chromatin organization during spermiogenesis, contributing to the functional organization of mature sperm.

  4. CTCF Binding Sites in the Herpes Simplex Virus 1 Genome Display Site-Specific CTCF Occupation, Protein Recruitment, and Insulator Function.

  5. Both LDB1 (show LDB1 ELISA Kits) and CTCF are required for enhancer-Car2 (show CA2 ELISA Kits) looping, and the domain of LDB1 (show LDB1 ELISA Kits) contacted by CTCF is necessary to rescue Car2 (show CA2 ELISA Kits) transcription in LDB1 (show LDB1 ELISA Kits)-deficient cells.

  6. CTCF physically associates with Wdr5 and further transcriptionally controls its expression by directly targeting the Wdr5 gene promoter.

  7. Since CTCF and cohesin are required for loop domain formation, our results suggest that chromatin loops are dynamic and frequently break and reform throughout the cell cycle.

  8. Nearly half of all DNase hypersensitivity sites (both constitutive and dynamic) overlap binding events of the bone-essential RUNX2 (show RUNX2 ELISA Kits) and/or the chromatin-related CTCF transcription factors.

  9. Chromatin immunoprecipitation-DNA sequence analysis was performed in adult cerebellum and Wiz peaks were found at promoters and transcription factor CTCF binding sites.

  10. CTCF knockdown attenuates fear-conditioning-induced hippocampal gene expression of key learning genes and loss of long-range interactions at the BDNF (show BDNF ELISA Kits) and Arc loci.

Human CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) interaction partners

  1. This study confirms that haploinsufficiency of CTCF causes distinct clinical features, and that a microdeletion encompassing CTCF could cause a recognisable CTCF deletion syndrome. Perturbed DNA methylation at CTCF binding sites, not at imprinted loci, may underlie the pathomechanism of the syndrome.

  2. structural studies show that the sequence-specific interactions between zinc fingers and CTCF-binding sites determine the directionality and conservation of CTCF recognition.

  3. CTCF may be a key factor that contributes to gene co-mutations in cancer.

  4. results support a model in which YY1 (show YY1 ELISA Kits) acts as an architectural protein to connect developmentally regulated looping interactions; the location of YY1 (show YY1 ELISA Kits)-mediated interactions may be demarcated in development by a preexisting topological framework created by constitutive CTCF-mediated interactions.

  5. The MeCP2, a protein whose mutated forms are involved in Rett syndrome; and CTCF, a constitutive transcriptional insulator.

  6. The results show that cohesin has an essential genome-wide function in mediating long-range chromatin interactions and support the hypothesis that cohesin creates these by loop extrusion, until it is delayed by CTCF in a manner dependent on PDS5 proteins, or until it is released from DNA by WAPL.

  7. CTCF-FOXM1 (show FOXM1 ELISA Kits) axis regulates tumour growth and metastasis in hepatocellular carcinoma cells.

  8. we show CTCF binding site mutations to be functional by demonstrating allele-specific reduction of CTCF binding to mutant alleles. While topologically associating domains with mutated CTCF anchors in melanoma contain differentially expressed cancer-associated genes, CTCF motif mutations appear generally under neutral selection

  9. CTCF-mediated long-range interactions are integral for a multitude of topological features of interphase chromatin, such as the formation of topologically associated domains, domain insulation, enhancer blocking and even enhancer function.

  10. Authors have identified two novel pro-tumorigenic roles (promoting cell survival and altering cell polarity) for genetic alterations of CTCF in endometrial cancer.

CTCF Antigen Profile

Antigen Summary

This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CTCF

  • CCCTC-binding factor (CTCF) antibody
  • CCCTC-binding factor (zinc finger protein) (ctcf) antibody
  • CCCTC-binding factor (ctcf) antibody
  • CCCTC-binding factor (Ctcf) antibody
  • AW108038 antibody
  • CTCF antibody
  • im:7152666 antibody
  • xctcf antibody

Protein level used designations for CTCF

transcriptional repressor CTCF , CCCTC-binding factor (zinc finger protein) , transcriptional repressor CTCF-like , 11-zinc finger protein , CTCFL paralog , 11 zinc finger transcriptional repressor

GENE ID SPECIES
100053363 Equus caballus
415104 Danio rerio
454169 Pan troglodytes
100101689 Xenopus (Silurana) tropicalis
100224119 Taeniopygia guttata
100350641 Oryctolagus cuniculus
100465401 Ailuropoda melanoleuca
13018 Mus musculus
10664 Homo sapiens
396274 Gallus gallus
479684 Canis lupus familiaris
517097 Bos taurus
83726 Rattus norvegicus
100623274 Sus scrofa
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