CD276 Molecule (CD276) ELISA Kits

The protein encoded by CD276 belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Additionally we are shipping CD276 Antibodies (224) and CD276 Proteins (46) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CD276 102657 Q8VE98
CD276 80381 Q5ZPR3
CD276 315716 Q7TPB4
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Top CD276 ELISA Kits at

Showing 4 out of 25 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.78 ng/mL 3.12-200 ng/mL Typical standard curve 96 Tests Log in to see 13 to 16 Days
Mouse 0.625 ng/mL 2.5-160 ng/mL   96 Tests Log in to see 15 to 18 Days
Rat 0.39 ng/mL 1.56-100 ng/mL   96 Tests Log in to see 15 to 18 Days
  1 kit Log in to see 11 to 12 Days

More ELISA Kits for CD276 Interaction Partners

Cow (Bovine) CD276 Molecule (CD276) interaction partners

  1. Anterior pituitary gland progenitor cells containing 4Ig-B7-H3 (CD276) may play a critical role in the immunoendocrine network.

Mouse (Murine) CD276 Molecule (CD276) interaction partners

  1. These results indicated an important role for B7-H3 in the development of Th1 and Th2 cells in a murine model of asthma and its proinflammatory effects are not dependent on TLR2 signaling.

  2. These results demonstrate that B7H3 substantially ameliorates LPS-induced Acute lung injury and this protection afforded by B7H3 is predominantly associated with its inhibitory effect on pulmonary PMN migration and infiltration

  3. Inhibition of the B7-H3 immune checkpoint limits tumor growth by enhancing cytotoxic lymphocyte function

  4. blockage of NF-kappaB p65 and/or MAPK p38 with their specific inhibitors strongly attenuated B7-H3-amplified inflammatory response with significantly reduced proinflammatory cytokine and chemokine production, and markedly ameliorated B7-H3-exacerbated disruption of blood-brain barrier and severity of disease status in S. pneumoniae-infected mice.

  5. CD276 is broadly expressed by tumor cells and tumor vasculature but Is dispensable for tumor growth.

  6. this study shows that B7-H3 participates in the development of acute pancreatitis

  7. Data show that B7-H3 protein is over-expressed in cerulein-induced acute pancreatitis, and anti-B7-H3 monoclonal antibody can attenuate the inflammation and alleviate the injury of pancreas and lung tissues.

  8. Ablation of B7-H3 but Not B7-H4 Results in Highly Increased Tumor Burden in a Murine Model of Spontaneous Prostate Cancer

  9. Murine B7-H3 is a positive co-stimulatory molecule in the regulation of T cell-mediated immune responses.

  10. B7-H3 inhibits T cell proliferation. FG loop of the IgV domain plays a critical role in this function. B7-H3 crystallized as an unusual dimer arising from the exchange of the G strands in the IgV domains of partner molecules

  11. The study investigates the role of B7-H3 in pancreatic cancer progression and shows that this protein promotes cancer cell migration and invasiveness in vitro and in vivo.

  12. Graft prolongation achieved by CTLA4 Ig was shortened both by B7-H3 blockade and the absence of recipient B7-H3.

  13. Macrophage-tumor cell interaction-induced membrane-bound B7-H3 represents a novel immune escape mechanism which links the pro-inflammatory response to immune tolerance in the tumor milieu.

  14. Exogenous administration of B7-H3 strongly amplifies the inflammatory response, exacerbates blood-brain barrier disruption, and aggravates the clinical disease status in Streptococcus pneumoniae-infected C3H/HeN wild-type mice.

  15. Tumour-associated B7-H3 directly augments CD8(+) T-cell effector function, possibly by ligation of TLT-2 on tumour-infiltrating CD8(+) T cells at the local tumour site.

  16. preferentially down-regulates t helper type 1-mediated immune responses

  17. B7-H3 serves as a negative regulator of T cell activation and function

  18. Plays a positive regulatory role in bone formation. In addition, has a dual role in the bone-immune interface.

  19. A role is established for B7-H3 in the costimulation of T cell-mediated tumor immunity in vivo.

  20. Dendritic cells expressing soluble mB7h3-hIg showed a significant reduced allo-stimulatory capability compared with controls. Soluble mB7h3-hIg also inhibited IL-2 and IFN-gamma production of allogenic T cells, suggesting therapeutic potential

Human CD276 Molecule (CD276) interaction partners

  1. Increased B7 protein expression by infiltrating immune cells was associated with disease progression, and specifically, the level of B7-H3 expression and localization of B7-H4 expression differed significantly among different stages of gastric carcinogenesis.

  2. B7-H3 is associated with the major vault protein (MVP) and activates MEK through MVP-enhancing B-RAF and MEK interaction. B7-H3 expression increases stem cell population by binding to MVP which regulates the activation of the MAPK kinase pathway. Depletion of MVP blocks the activation of MEK induced by B7-H3 and dramatically inhibits B7-H3 induced stem cells.

  3. B7-H3 might be an independent risk factor for 5-year mortality for Congenital Heart Disease (CHD) patients. Serum levels of B7-H3 were related to long-term major cardiovascular events and 5-year mortality of CHD patients.

  4. Study indicates that breast cancer patients have detectable circulating epithelial tumor cells (CETCs) with a high frequency of B7-H3 expression regardless of the stage of the disease. B7-H3 seems to be an important factor in immune evasion and may thus be a promising target for anticancer therapies.

  5. it is likely that B7-H3 plays an important role in cancer diagnosis and treatment, aside from its role as a co-stimulatory molecule--{REVIEW}

  6. High B7-H3 expression is associated with phyllodes tumors.

  7. characterization of the expression pattern and biological function of B7-H3 in brain gliomas; B7-H3 expression is regulated by multiple mechanisms and is potentially involved in the T-cell receptor signaling pathway; higher B7-H3 expression indicates a worse prognosis for glioma patients

  8. High expression level of B7H3 in muscleinvasive bladder cancer (MIBC) tissues is associated with a poor clinico-pathological status and poor prognosis, and promotes the development of MIBC in vitro and in vivo.

  9. Tumor B7-H3 expression was significantly higher in immunocompetent vs. immunosuppressed patients, largely driven by very low expression in HIV+ patients.

  10. Colorectal cancer (CRC) patients expressing both high B7-H3 and high B3GALT4 contributed to a significant decrease in overall survival. The expression of B3GALT4 in CRC is positively correlated with B7-H3 expression in vitro. B7-H3/B3GLAT4 may be used as dual prognostic biomarkers for CRC.

  11. this study shows reduced sB7-H3 expression in the peripheral blood of systemic lupus erythematosus patients

  12. High B7-H3 expression is associated with cervical cancer invasiveness.

  13. IDH1 and B7H3 cannot be used as independent prognostic factors, co-expression of IDH1 and B7H3 significantly correlated with the prognosis of CRC patients and may serve as a combined predictive marker. Thus, the correlation between IDH1 and B7H3 has been proven in vivo and in vitro.

  14. Our findings revealed that B7-H3 affect ovarian cancer progression through the Jak2/Stat3 pathway, indicating that B7-H3 has the potential to be a useful prognostic marker.

  15. B7-H3 protein is expressed in the majority of NSCLCs and is associated with smoking history. High levels of B7-H3 protein have a negative prognostic impact in lung carcinomas. Coexpression of B7-H3 with PD-L1 and B7-H4 is relatively low, suggesting a nonredundant biological role of these targets.

  16. metastatic melanoma cells with knockdown expression of B7-H3 showed modest decrease in proliferation and glycolytic capacity.

  17. results suggest that B7-H3 may be a valuable biomarker in determining tumor progression and prognosis of intrahepatic cholangiocarcinoma

  18. these results demonstrate that sB7-H3 promotes invasion and metastasis through the TLR4/NF-kappaB pathway in pancreatic carcinoma

  19. Inhibition of the B7-H3 immune checkpoint limits tumor growth by enhancing cytotoxic lymphocyte function

  20. Higher B7-H3 expression correlates with Gleason grade, prostate cancer stage and poor oncologic outcomes in prostatectomy cohorts. B7-H3 expression appears to be related to androgen signaling as well as the immune reactome.

CD276 Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CD276 Molecule (CD276) ELISA Kits

  • CD276 molecule (CD276) antibody
  • CD276 molecule S homeolog (cd276.S) antibody
  • CD276 molecule (cd276) antibody
  • CD276 antigen (Cd276) antibody
  • Cd276 molecule (Cd276) antibody
  • 4Ig-B7-H3 antibody
  • 6030411F23Rik antibody
  • AU016588 antibody
  • B7-H3 antibody
  • B7H3 antibody
  • B7RP-2 antibody
  • sc:d0645 antibody
  • zgc:158279 antibody

Protein level used designations for CD276 Molecule (CD276) ELISA Kits

CD276 molecule , CD276 antigen-like , CD276 antigen homolog , CD276 antigen , B7 homolog 3 , B7-H3 , costimulatory molecule

100471106 Ailuropoda melanoleuca
447379 Xenopus laevis
467818 Pan troglodytes
487638 Canis lupus familiaris
508656 Bos taurus
699877 Macaca mulatta
791140 Danio rerio
100195762 Salmo salar
100397167 Callithrix jacchus
100446767 Pongo abelii
102657 Mus musculus
415315 Gallus gallus
80381 Homo sapiens
315716 Rattus norvegicus
Selected quality suppliers for CD276 (CD276) ELISA Kits
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