anti-CD48 Molecule (CD48) Antibodies

CD48 encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. Additionally we are shipping CD48 Proteins (25) and CD48 Kits (15) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CD48 12506 P18181
CD48 245962 P10252
CD48 962 P09326
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Top anti-CD48 Antibodies at antibodies-online.com

Showing 10 out of 310 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL 2 to 3 Days
$289.00
Details
Human Mouse APC FACS, IHC (p), IP, WB Surface staining of human peripheral blood cells with anti-CD48 (MEM-102) Alexa Fluor® 700. 100 Tests 5 to 7 Days
$497.45
Details
Human Mouse Biotin FACS, IHC (p), IP, WB Surface staining of human peripheral blood cells with anti-CD48 (MEM-102) Alexa Fluor® 700. 0.1 mg 5 to 7 Days
$428.84
Details
Human Mouse Un-conjugated FACS, IHC (p), IP, WB Surface staining of human peripheral blood cells with anti-CD48 (MEM-102) Alexa Fluor® 700. 0.1 mg 5 to 7 Days
$343.07
Details
Human Mouse FITC FACS, IHC (p), IP, WB Surface staining of human peripheral blood cells with anti-CD48 (MEM-102) Alexa Fluor® 700. Surface staining of human peripheral blood with anti-CD48 (MEM-102) FITC. 100 Tests 5 to 7 Days
$428.84
Details
Human Mouse PE FACS, IHC (p), IP, WB Surface staining of human peripheral blood cells with anti-CD48 (MEM-102) Alexa Fluor® 700. 100 Tests 5 to 7 Days
$497.45
Details
Human Rabbit Un-conjugated WB Western blot analysis of CD48 expression in CEM whole cell lysates ( Lane 1). CD48 at 39KD was detected using rabbit anti- CD48 Antigen Affinity purified polyclonal antibody (Catalog #) at 0.5 µg/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002). 100 μg 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IP, ELISA, WB 100 μL 14 to 16 Days
$247.82
Details
Human Mouse Un-conjugated FACS, IHC (p), IP, WB   0.1 mg 6 to 8 Days
$258.50
Details
Human Rabbit Un-conjugated ELISA, IHC (p), WB Immunohistochemistry (IHC) analysis of paraffin-embedded Human Lung Cancer, antibody was diluted at 1:100. 100 μL Available
$363.46
Details

Top referenced anti-CD48 Antibodies

  1. Human Monoclonal CD48 Primary Antibody for FACS, IHC (p) - ABIN192135 : Bazil, Stefanová, Hilgert, Kristofová, Van?k, Bukovský, Horejsí: Monoclonal antibodies against human leucocyte antigens. III. Antibodies against CD45R, CD6, CD44 and two newly described broadly expressed glycoproteins MEM-53 and MEM-102. in Folia biologica 1990 (PubMed)
    Show all 11 Pubmed References

  2. Human Monoclonal CD48 Primary Antibody for FACS, IHC (p) - ABIN94158 : Drbal, Moertelmaier, Holzhauser, Muhammad, Fuertbauer, Howorka, Hinterberger, Stockinger, Schütz: Single-molecule microscopy reveals heterogeneous dynamics of lipid raft components upon TCR engagement. in International immunology 2007 (PubMed)
    Show all 10 Pubmed References

  3. Human Monoclonal CD48 Primary Antibody for FACS, IHC (p) - ABIN1302987 : Munitz, Bachelet, Eliashar, Khodoun, Finkelman, Rothenberg, Levi-Schaffer: CD48 is an allergen and IL-3-induced activation molecule on eosinophils. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)
    Show all 9 Pubmed References

  4. Human Monoclonal CD48 Primary Antibody for FACS, IHC (p) - ABIN94157 : Angelisová, Drbal, Horejsí, Cerný: Association of CD10/neutral endopeptidase 24.11 with membrane microdomains rich in glycosylphosphatidylinositol-anchored proteins and Lyn kinase. in Blood 1999 (PubMed)
    Show all 9 Pubmed References

  5. Human Monoclonal CD48 Primary Antibody for FACS, IHC (p) - ABIN94159 : Lee, Forman, McNerney, Stepp, Kuppireddi, Guzior, Latchman, Sayegh, Yagita, Park, Oh, Wülfing, Schatzle, Mathew, Sharpe, Kumar: Requirement of homotypic NK-cell interactions through 2B4(CD244)/CD48 in the generation of NK effector functions. in Blood 2006 (PubMed)
    Show all 9 Pubmed References

  6. Mouse (Murine) Monoclonal CD48 Primary Antibody for BR, Func - ABIN1177003 : Kato, Koyanagi, Okada, Takanashi, Wong, Williams, Okumura, Yagita: CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation. in The Journal of experimental medicine 1992 (PubMed)
    Show all 3 Pubmed References

  7. Mouse (Murine) Monoclonal CD48 Primary Antibody for FACS - ABIN2480672 : Robinson: Ragdale Hall Health Hydro. in Nursing mirror and midwives journal 1976 (PubMed)
    Show all 4 Pubmed References

  8. Mouse (Murine) Monoclonal CD48 Primary Antibody for FACS - ABIN2480673 : Lapaque, Forquet, de Chastellier, Mishal, Jolly, Moreno, Moriyon, Heuser, He, Gorvel: Characterization of Brucella abortus lipopolysaccharide macrodomains as mega rafts. in Cellular microbiology 2006 (PubMed)
    Show all 4 Pubmed References

  9. Mouse (Murine) Monoclonal CD48 Primary Antibody for FACS - ABIN2480675 : Kashiwakura, Sakurai, Kanno, Hashiguchi, Kobayashi, Kurosu, Tokudome, Kobata, Kojima: CD2-mediated regulation of peripheral CD4(+)  CD25(+) regulatory T-cell apoptosis accompanied by down-regulation of Bim. in Immunology 2013 (PubMed)
    Show all 4 Pubmed References

  10. Human Monoclonal CD48 Primary Antibody for FACS, IHC (p) - ABIN532767 : Baitsch, Legat, Barba, Fuertes Marraco, Rivals, Baumgaertner, Christiansen-Jucht, Bouzourene, Rimoldi, Pircher, Rufer, Matter, Michielin, Speiser: Extended co-expression of inhibitory receptors by human CD8 T-cells depending on differentiation, antigen-specificity and anatomical localization. in PLoS ONE 2012 (PubMed)

More Antibodies against CD48 Interaction Partners

Mouse (Murine) CD48 Molecule (CD48) interaction partners

  1. Molecular dynamic simulation explains unbinding and unfolding of CD48-2B4 protein complexes.

  2. These data demonstrate the important role of CD48 in SA/exotoxins-eosinophil activating interactions that can take place during allergic responses and indicate CD48 as a novel therapeutic target for allergy and especially of AD.

  3. ORMDL3 promotes eosinophil trafficking and activation via regulation of CD18, CD49d, and CD48.

  4. Ox-LDL significantly promoted the interaction of natural killer cells and dendritic cells via CD48-2B4 contact-dependent mechanisms.

  5. B6-specific background genes modulate the effect of CD48 on lupus nephritis in a recessive manner

  6. CD48 plays a vital role as an environmental sensor for regulating hematopoietic stem cells and progenitor cell numbers and inhibiting tumor development

  7. CD48 on surrounding NK or non-NK cells serves primarily as a ligand to stimulate 2B4 on the adjacent NK cells in mice

  8. CD137 and CD28 can promote bcl-2 expression at both mRNA and protein level in T cells.

  9. molecular mechanism of heterophilic adhesion between the murine T-cell adhesion glycoprotein CD2 and its ligand CD48

  10. CD48 interactions with NK cell receptor 2B4 among neighboring T cells during T cell priming augment CTL lysis of their specific targets.

  11. Analysis of the ligand-receptor pairs involved in induction of germline transcripts (Igamma2a) necessary for switch recombination revealed that expression of CD48 on B cells and ligands CD2 and CD244 on NK cells are able to stimulate Igamma2a

  12. compare the relative contributions of MHC class I and CD48 to NK cell self-tolerance; and CD244 regulates NK cell tolerance to normal cells in vivo; evidence for MHC-independent NK self-recognition in a bone marrow rejection assay

  13. Cell surface receptors of the SLAM family, including CD150, CD244, and CD48, were differentially expressed among functionally distinct hematopoietic progenitor cells.

  14. Review of recent studies suggests an important role for interactions between 2B4 and CD48 in the course of T cell activation and proliferation

  15. T cell-induced experimental colitis is ameliorated only when CD48 is absent from both T cells and antigen-presenting cells.

  16. the mechanism of signal transduction by CD244 is to regulate FYN kinase recruitment and/or activity and the outcome of CD48/CD244 interactions is determined by which other receptors are engaged.

  17. nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse

Human CD48 Molecule (CD48) interaction partners

  1. soluble CD48 levels were significantly elevated in patients with nonallergic asthma compared to control and to the allergic asthma cohort

  2. mCD48 and sCD48 are differentially expressed in the peripheral blood of asthma patients of varying severity. sCD48 inhibits CD244-mediated eosinophil activation. These findings suggest that CD48 may play an important role in human asthma.

  3. The present study provides further insights into the role of the 2B4-CD48 interaction in the fine regulation of CD8(+) T-cell effector function upon antigenic stimulation.

  4. Data show that 2B4 not only can bind to CD48 in trans but also interacts with CD48 in cis by using the same binding interface. Also, the results demonstrated that constitutive phosphorylation of 2B4 occurs only in the presence of CD48, and that cis binding is sufficient to induce substantial levels of baseline phosphorylation.

  5. Our data indicate sCD48 as a SEB-induced 'decoy' receptor derived from eosinophil and therefore as a potential anti-inflammatory tool in S. aureus-induced eosinophil inflammation often associated with allergy.

  6. CD48 expression was increased in patients with a short disease duration compared to both controls and patients with longer disease duration. In patients with short disease duration, increased CD48 expression was associated with alveolar inflammation.

  7. These data demonstrate the important role of CD48 in SA/exotoxins-eosinophil activating interactions that can take place during allergic responses and indicate CD48 as a novel therapeutic target for allergy and especially of AD.

  8. Blockade of 2B4/CD48 interaction resulted in improvement in function via perforin expression and degranulation as measured by CD107a surface mobilization on HTLV-1 specific CD8+ T cells.

  9. we propose that SLAMF2 engagement regulates adaptive immune responses

  10. Monocyte-induced natural killer cell dysfunction was markedly attenuated by blocking CD48 receptor 2B4 on NK cells, but not by blockade of NKG2D and NKp30.

  11. replication study of association of 2 SNPs in HERV-K18 and 19 tagSNPs in CD48 with schizophrenia (SZ)and type 2 diabetes (T2D) in patients with SZ in 2 Danish samples; no association was found with SZ or with T2D among individuals with SZ for any of the SNPs

  12. Stimulation of CD48 induces rearrangement of signaling factors in lipid rafts, Lck-kinase activity, and tyrosine phosphorylation.

  13. The ligand (CD48) of the 2B4 receptor can exert both activating and inhibiting signals; natural killer (NK) cells might be at risk for self-killing were it not for the inhibiting signals generated by the 2B4-CD48 interaction.

  14. CM1-induced apoptosis is achieved via different initiation pathways, which are cell-type dependent

  15. Signal-dependent adhesion of resting NK cells initiated by expression of ICAM-1 is greatly enhanced by coexpression of CD48, even in the absence of cytokines.

  16. Engagement of natural killer (NK) cell receptor 2B4 by its counterreceptor, CD48, expressed on target cells leads to an inhibition in NK cytotoxicity independent of signaling lymphocytic activation molecule-associated protein (SAP) expression.

  17. IL-18, IL-18 receptor alpha, and CD48 complex formation via glycosylphosphatidylinositol anchor glycan triggers binding to IL-18 receptor beta, and thereby induces intracellular signal transduction and IFN-gamma production.

  18. Review of recent studies suggests an important role for interactions between 2B4 and CD48 in the course of T cell activation and proliferation

  19. 2B4 (CD244) can stimulate NK cell cytotoxicity and cytokine production by interacting with NK cell expressed CD48 and adds CD48 to the growing number of activating NK cell receptors

  20. CD48 is an interleukin (IL)-3-induced activating receptor on eosinophils and may be involved in promoting allergic inflammation.

CD48 Antigen Profile

Protein Summary

This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-CD48 Molecule (CD48) Antibodies

  • CD48 antigen (Cd48) antibody
  • Cd48 molecule (Cd48) antibody
  • CD48 molecule (CD48) antibody
  • AI449234 antibody
  • AW610730 antibody
  • Bcm-1 antibody
  • BCM1 antibody
  • BLAST antibody
  • BLAST-1 antibody
  • BLAST1 antibody
  • hCD48 antibody
  • mCD48 antibody
  • MEM-102 antibody
  • Sgp-60 antibody
  • SLAMF2 antibody

Protein level used designations for anti-CD48 Molecule (CD48) Antibodies

BCM1 surface antigen , HM48-1 , MRC OX-45 surface antigen , SLAM family member 2 , signaling lymphocytic activation molecule 2 , BLAST-1 , CD48 antigen , B-lymphocyte activation marker BLAST-1 , CD48 antigen (B-cell membrane protein) , TCT.1 , leukocyte antigen MEM-102

GENE ID SPECIES
12506 Mus musculus
245962 Rattus norvegicus
962 Homo sapiens
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