anti-CD5 Molecule-Like (CD5L) Antibodies

May play a role in the regulation of the immune system. Additionally we are shipping CD5L Kits (47) and CD5L Proteins (20) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CD5L 922 O43866
CD5L 11801 Q9QWK4
CD5L 310693  
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Top anti-CD5L Antibodies at antibodies-online.com

Showing 10 out of 130 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry: CD5L Antibody [NBP2-39061] - Staining of human liver shows distinct cytoplasmic positivity in Kupffer cells. Western Blot: CD5L Antibody [NBP2-39061] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: RT-4.Lane 3: U-251 MG.Lane 4: Human Plasma 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Human Tonsil (formalin-fixed, paraffin-embedded) stained with CD5L antibody ABIN214596 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-CD5L antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Log in to see 11 to 14 Days
$561.00
Details
Human Rabbit Un-conjugated WB CD5L Antibody (N-term) (ABIN1881187) western blot analysis in A549 cell line lysates (35 µg/lane). This demonstrates the CD5L antibody detected the CD5L protein (arrow). 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 3 to 4 Days
$372.71
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 3 to 4 Days
$372.71
Details
Mouse Rabbit Un-conjugated ELISA   100 μg Log in to see 14 to 16 Days
$183.12
Details
Human Mouse Un-conjugated IP, ELISA, WB CD5L monoclonal antibody (M01), clone 1C8. Western Blot analysis of CD5L expression in HL-60 . CD5L monoclonal antibody (M01), clone 1C8. Western Blot analysis of CD5L expression in different cell lines. 100 μg Log in to see 11 to 12 Days
$364.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of CD5L expression in Raji cell lysate,The lane on the left is treated with the antigen-specific peptide. 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$687.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse lymphoma tissue labeled with Anti-CD5L/Api6 Polyclonal Antibody, Unconjugated (ABIN740985) at 1:200 followed by conjugation to the secondary antibody and DAB staining Paraformaldehyde-fixed, paraffin embedded rat spleen, Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes, Blocking buffer (normal goat serum) at 37°C for 30min, Antibody incubation with CD5L Polyclonal Antibody, Unconjugated  at 1:400 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining. 100 μL Log in to see 3 to 7 Days
$317.90
Details

Top referenced anti-CD5L Antibodies

  1. Human Polyclonal CD5L Primary Antibody for WB - ABIN1881187 : Qu, Du, Li, Yan: Myeloid-specific expression of Api6/AIM/Sp alpha induces systemic inflammation and adenocarcinoma in the lung. in Journal of immunology (Baltimore, Md. : 1950) 2009 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal CD5L Primary Antibody for WB - ABIN550286 : Miyazaki, Hirokami, Matsuhashi, Takatsuka, Naito: Increased susceptibility of thymocytes to apoptosis in mice lacking AIM, a novel murine macrophage-derived soluble factor belonging to the scavenger receptor cysteine-rich domain superfamily. in The Journal of experimental medicine 1999 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal CD5L Primary Antibody for WB - ABIN550285 : Haruta, Kato, Hashimoto, Minjares, Kennedy, Uto, Yamauchi, Kobayashi, Yusa, Müller, Hayashi, Miyazaki: Association of AIM, a novel apoptosis inhibitory factor, with hepatitis via supporting macrophage survival and enhancing phagocytotic function of macrophages. in The Journal of biological chemistry 2001 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal CD5L Primary Antibody for IHC (p), WB - ABIN2472165 : Ruibal Francisco, Seara Aguilar, Fernández Méndez, Noya Beiroa, Reverte Blanc, Valor García, Cabranes Díaz, Casado de Frías: [Nocturnal use of pirenzepine by a group of insulin dependent juvenile diabetics]. in Anales españoles de pediatría 1992 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal CD5L Primary Antibody for IHC (p), WB - ABIN2472166 : Sarrias, Roselló, Sánchez-Barbero, Sierra, Vila, Yélamos, Vives, Casals, Lozano: A role for human Sp alpha as a pattern recognition receptor. in The Journal of biological chemistry 2005 (PubMed)
    Show all 2 Pubmed References

More Antibodies against CD5L Interaction Partners

Human CD5 Molecule-Like (CD5L) interaction partners

  1. CD5L is upregulated in hepatocellular carcinoma. CD5L promotes liver cancer cell proliferation and antiapoptotic responses by binding to HSPA5.

  2. Low serum AIM levels in patients who have previously experienced peritoneal dialysis-related peritonitis.

  3. Taken together with our results on the aberrant ex vivo production of CD5L, this study has provided new evidence for the potential immunopathological role of CD5L in the exacerbation of SLE disease, and circulating concentration of CD5L may act as a potential disease marker for the monitoring of disease severity and therapeutic effects in SLE patients.

  4. AIM enhances intratubular debris clearance and ameliorates acute kidney injury via interaction with KIM-1.

  5. The present study provides the first evidence that apoptosis inhibitor of macrophages binds to IGFBP2, 3 and 4.

  6. CD36 is involved in autophagy; the CD5L-CD36 axis has a role in the induction of macrophage autophagy

  7. CD5L is a key protein in the control of immune homeostasis and inflammatory disease. (Review)

  8. Apoptosis inhibitor of macrophage levels were markedly higher in patients with advanced liver damage, regardless of disease type, and correlated significantly with multiple parameters representing liver function.

  9. AIM contributes to key macrophage responses to M. tuberculosis

  10. Our data represent the first evidence that human AIM is involved in macrophage survival, adhesion, and foam cell formation

  11. N-glycosylation plays important roles in the secretion and lipolytic function of AIM

  12. AIM is involved in the progression of MetS in both an advancing and inhibitory fashion. Regulation of AIM could therefore be therapeutically applicable for MetS.

  13. Spalpha is an active constituent of the innate immune response of the host

  14. CD5L and ApoE were significantly up-regulated or down-regulated, respectively, in the plasma from AD patients compared with that from healthy donors.

  15. Dysregulation of myeloid cell populations by extracellular transgene Api6 signaling leads to abnormal myelopoiesis and lung cancer in bitransgenic mice.

Mouse (Murine) CD5 Molecule-Like (CD5L) interaction partners

  1. AIM appears to be involved in the prevention and repair process of a peritoneal dialysis-related fungal peritonitis.

  2. AIM/CD5L-deficient mice demonstrated a smaller infarct size and less of an inflammatory response via inflammatory pathways after myocardial infarction; these data provide the first evidence that AIM/CD5L plays an important role in the inflammatory responses after myocardial injury

  3. AIM enhances intratubular debris clearance and ameliorates acute kidney injury via interaction with KIM-1.

  4. CD5L as a critical regulator that distinguishes Th17 functional states and identified T cell lipid metabolism as an integral component of the pathways regulating Th17 cell pathogenicity.

  5. plays a general homeostatic role by supporting innate immunity during pathogen aggression

  6. the assembled p40-CD5L heterodimer does not recapitulate the biological activity of IL-12.

  7. AIM contributes to key macrophage responses to M. tuberculosis

  8. AIM-IgM association plays a critical role in the obesity-associated autoimmune process.

  9. SREBP-1a specifically activates the Api6 gene through a binding site in its proximal promoter, thus establishing the Api6 gene as a newly identified SREBP-1a target gene

  10. N-glycosylation plays important roles in the secretion and lipolytic function of AIM

  11. AIM induces lipolysis in a manner distinct from that of hormone-dependent lipolysis, without activation or augmentation of lipases.

  12. Apoptosis inhibitor of macrophage (AIM) is required for obesity-associated recruitment of inflammatory macrophages into adipose tissue.

  13. AIM binds to cytosolic FAS protein at various regions responsible for elongation of fatty acids, release of synthesized palmitate, and stabilization of FAS dimerization.

  14. The protein inhibits apoptosis of T cells and NKT cells in Corynebacterium-induced granuloma formation in mice.

  15. Api6 production facilitates macrophage survival within atherosclerotic lesions and that loss of Api6 decreases early lesion development by increasing macrophage apoptosis

  16. Bacterial lipoteichoic acid might affect the pathogenesis of epithelial inflammation followed by fibrosis in systemic multifocal epithelial inflammations in chronic colitis-harboring TCR alpha(-/-) x AIM(-/-) mice

CD5L Antigen Profile

Protein Summary

May play a role in the regulation of the immune system. Seems to play a role as an inhibitor of apoptosis.

Gene names and symbols associated with CD5L

  • CD5 molecule like (CD5L) antibody
  • CD5 antigen-like (Cd5l) antibody
  • Cd5 molecule-like (Cd5l) antibody
  • CD5 molecule-like (CD5L) antibody
  • scavenger receptor cysteine-rich domain superfamily protein-like (LOC100375137) antibody
  • CD5 molecule like (Cd5l) antibody
  • 1/6 antibody
  • AAC-11 antibody
  • AI047839 antibody
  • AIM antibody
  • Api6 antibody
  • CD5L antibody
  • CT2 antibody
  • Pdp antibody
  • PRO229 antibody
  • Sp-alpha antibody
  • Spalpha antibody

Protein level used designations for CD5L

CD5 antigen-like , CD5 antigen-like (scavenger receptor cysteine rich family) , CT-2 , apoptosis inhibitor 6 , igM-associated peptide , AIM/Spalpha , Pdp 1/6 , apoptosis inhibitor expressed by macrophages , CD5 molecule-like

GENE ID SPECIES
922 Homo sapiens
11801 Mus musculus
310693 Rattus norvegicus
100392030 Callithrix jacchus
100479381 Ailuropoda melanoleuca
457415 Pan troglodytes
528593 Bos taurus
609953 Canis lupus familiaris
718856 Macaca mulatta
776284 Gallus gallus
100375137 Saccoglossus kowalevskii
100443069 Pongo abelii
100596474 Nomascus leucogenys
100154019 Sus scrofa
100729988 Cavia porcellus
103350036 Oryctolagus cuniculus
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