anti-CD6 (CD6) Antibodies

CD6 encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells.

list all antibodies Gene Name GeneID UniProt
Anti-Mouse CD6 CD6 12511 Q61003
Anti-Human CD6 CD6 923 P30203
Anti-Rat CD6 CD6 25752  
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Top anti-CD6 Antibodies at antibodies-online.com

Showing 10 out of 482 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated FACS, IHC (p), IP, WB Surface staining of human peripheral blood cells with anti-human CD6 (MEM-98) FITC. 0.1 mg Log in to see 5 to 7 Days
$253.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse PE FACS, IHC (p), IP, WB Surface staining of human peripheral blood cells with anti-human CD6 (MEM-98) FITC. 100 Tests Log in to see 5 to 7 Days
$366.85
Details
Human Mouse Un-conjugated IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Immunohistochemical analysis of paraffin-embedded stomach cancer tissues using CD6 mouse mAb with DAB staining. 100 μg Log in to see 2 to 3 Days
$430.10
Details
Human Mouse Un-conjugated ELISA, IHC, WB 100 μg Log in to see 7 to 9 Days
$551.83
Details
Rat Mouse Un-conjugated IHC (fro), FACS, IHC (p), IP   0.1 mg Log in to see 15 to 18 Days
$130.32
Details
Rat Mouse Un-conjugated FACS, IHC (fro), IP, IHC Flow Cytometry: CD6 Antibody (OX-52) [ABIN2599906] - Rat spleen cells. Flow Cytometry: CD6 Antibody (OX-52) [ABIN2599906] - Analysis using the Biotin conjugate of ABIN2599906. Staining of rat spleen cells. 0.25 mg Log in to see 7 to 9 Days
$444.19
Details
Human Mouse Un-conjugated FACS, IHC, IHC (p), IP, WB Human Spleen (formalin-fixed, paraffin-embedded) stained with CD6 antibody ABIN294221 at 10 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$484.00
Details
Human Goat Alexa Fluor 488 FACS Detection of CD6 in Human Whole Blood Lymphocytes by Flow Cytometry. Human whole blood lymphocytes were stained with Goat Anti-Human CD6 Alexa Fluor 488-conjugated Antigen Affinity-purified Polyclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$328.90
Details
Human Rabbit Un-conjugated WB Western Blot: CD6 Antibody [NBP1-33753] - Sample (30 ug of whole cell lysate) A: H1299 B: Hela 7. 5% SDS PAGE; antibody diluted at 1:1000. 0.1 mL Log in to see 7 to 9 Days
$514.63
Details

Top referenced anti-CD6 Antibodies

  1. Rat (Rattus) Monoclonal CD6 Primary Antibody for IHC (fro), FACS - ABIN2689349 : Lawetzky, Tiefenthaler, Kubo, Hünig: Identification and characterization of rat T cell subpopulations expressing T cell receptors alpha/beta and gamma/delta. in European journal of immunology 1990 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal CD6 Primary Antibody for FACS, IHC (p) - ABIN94206 : Castro, Oliveira, Nunes, Fabre, Barbosa, Peixoto, Brown, Parnes, Bismuth, Moreira, Rocha, Carmo: Extracellular isoforms of CD6 generated by alternative splicing regulate targeting of CD6 to the immunological synapse. in Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)
    Show all 5 Pubmed References

  3. Pig (Porcine) Monoclonal CD6 Primary Antibody for IHC (fro), FACS - ABIN2472176 : Pescovitz, Book, Aasted, Dominguez, Bullido, Trebichavsky, Novikov, Valpotic, Nielsen, Arn, Sachs, Lunney, Boyd, Walker, Lee, Petrinec, Saalmüller: Analyses of monoclonal antibodies reacting with porcine wCD6: results from the Second International Swine CD Workshop. in Veterinary immunology and immunopathology 1998 (PubMed)
    Show all 4 Pubmed References

  4. Human Monoclonal CD6 Primary Antibody for IHC, ELISA - ABIN1098118 : Alonso, Buors, Le Dantec, Hillion, Pers, Saraux, Montero, Marianowski, Loisel, Devauchelle, Youinou, Renaudineau: Aberrant expression of CD6 on B-cell subsets from patients with Sjögren's syndrome. in Journal of autoimmunity 2010 (PubMed)
    Show all 4 Pubmed References

  5. Rat (Rattus) Monoclonal CD6 Primary Antibody for FACS, IHC (fro) - ABIN259990 : Crook, Hunt: Enrichment of early fetal-liver hemopoietic stem cells of the rat using monoclonal antibodies against the transferrin receptor, Thy-1, and MRC-OX82. in Developmental immunology 1996 (PubMed)
    Show all 2 Pubmed References

  6. Human Monoclonal CD6 Primary Antibody for IHC (fro), FACS - ABIN2689348 : Bott, Doshi, Li, McMurtry, Sanders, Fox: Transcriptional regulation of CD6 expression on human T lymphocytes by phorbol ester. in Journal of immunology (Baltimore, Md. : 1950) 1994 (PubMed)
    Show all 2 Pubmed References

  7. Human Monoclonal CD6 Primary Antibody for FACS, IHC (p) - ABIN192058 : Hassan, Simmonds, Clarkson, Hanrahan, Puklavec, Bomb, Barclay, Brown: CD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76. in Molecular and cellular biology 2006 (PubMed)
    Show all 5 Pubmed References

  8. Human Monoclonal CD6 Primary Antibody for FACS - ABIN2472171 : Pauleikhoff, Harper, Marshall, Bird: Aging changes in Bruch's membrane. A histochemical and morphologic study. in Ophthalmology 1990 (PubMed)
    Show all 4 Pubmed References

  9. Human Monoclonal CD6 Primary Antibody for FACS, IP - ABIN2472169 : Bazil, Stefanová, Hilgert, Kristofová, Van?k, Bukovský, Horejsí: Monoclonal antibodies against human leucocyte antigens. III. Antibodies against CD45R, CD6, CD44 and two newly described broadly expressed glycoproteins MEM-53 and MEM-102. in Folia biologica 1990 (PubMed)
    Show all 4 Pubmed References

  10. Human Monoclonal CD6 Primary Antibody for FACS - ABIN1383806 : Cortés, Deschaseaux, Uchida, Labastie, Friera, He, Charbord, Péault: HCA, an immunoglobulin-like adhesion molecule present on the earliest human hematopoietic precursor cells, is also expressed by stromal cells in blood-forming tissues. in Blood 1999 (PubMed)

More Antibodies against CD6 Interaction Partners

Mouse (Murine) CD6 interaction partners

  1. Results indicate Cdcp1 (CD318 (show CDCP1 Antibodies)) as a ligand of T-cell differentiation antigen CD6 (CD6) and a potential target for the diagnosis and treatment of autoimmune diseases.

  2. These results suggest that (i) CD6 is a negative regulator of T-cell activation, (ii) at the same time, CD6 is a positive regulator of activated T-cell survival/proliferation and infiltration; and (iii) CD6 is a potential new target for treating multiple sclerosis (MS)and potentially other T-cell-driven autoimmune conditions.

  3. these data indicate that CD6 modulates the threshold for thymocyte selection and the generation and/or function of several peripheral T cell subpopulations, including T reg (show KCNH2 Antibodies) cells

  4. results reveal an unexpected role of CD6 in the pathogenesis of intestinal IR-induced injury by regulating the self-renewal of B1a cells.

  5. this analysis identified 65 proteins not associated before with the Zap70 (show ZAP70 Antibodies)-Lat (show LAT Antibodies)-SLP-76 (show LCP2 Antibodies) network and thus should provide cues for future functional experiments.

Human CD6 interaction partners

  1. These results suggest that (i) CD6 is a negative regulator of T-cell activation, (ii) at the same time, CD6 is a positive regulator of activated T-cell survival/proliferation and infiltration; and (iii) CD6 is a potential new target for treating multiple sclerosis (MS)and potentially other T-cell-driven autoimmune conditions.

  2. These data are consistent with a model in which bivalent recruitment of a GADS (show GRAP2 Antibodies)/SLP-76 (show LCP2 Antibodies) complex is required for costimulation by CD6.

  3. Data indicate that the T cell-specific adaptor protein (TSAd (show SH2D2A Antibodies)) SH2 domain interacts with CD6 antigen and linker for activation of T cells (show LAT Antibodies) protein (LAT (show ORC3 Antibodies)) phosphotyrosine (pTyr) peptides.

  4. Results from recent genetic association studies provide evidence for a role of CD6 in multiple sclerosis and in rheumatoid arthritis pathogenesis. [review]

  5. Study provides evidence on the role of CD6, a lymphocyte-specific surface receptor from to the ancient and highly conserved Scavenger Receptor Cysteine-Rich (SRCR) superfamily, as a pattern recognition receptor, and the functional consequences this may have on T cell activation and differentiation. [review]

  6. Data show the multiple aspects that determine the nature of the signals transmitted via CD6 and the context that may define a dual role for this important T cell surface molecule (show CD8A Antibodies). [review]

  7. Data show a role for extracellular and intracellular interactions of CD6 in lateral movement in response to T cell activation. [review]

  8. The binding sites on CD6 and CD166 (show ALCAM Antibodies) have been characterized to show that a SNP in CD6 causes glycosylation that hinders the CD6/CD166 (show ALCAM Antibodies) interaction.

  9. CD6 regulatory T cells are characterized by CD6 expression and FOXP3 (show FOXP3 Antibodies) expression.

  10. interaction of Galectin-1 (show LGALS1 Antibodies) and -3 with CD6

CD6 Antigen Profile

Protein Summary

This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-CD6 (CD6) Antibodies

  • CD6 antigen (Cd6) antibody
  • CD6 molecule (CD6) antibody
  • Cd6 molecule (Cd6) antibody
  • OX52 antibody
  • TP120 antibody

Protein level used designations for anti-CD6 (CD6) Antibodies

T-cell differentiation antigen CD6 , CD6 antigen , T12 , CD6 antigen, Tp120

GENE ID SPECIES
12511 Mus musculus
923 Homo sapiens
25752 Rattus norvegicus
100513519 Sus scrofa
282881 Bos taurus
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