CD6 (CD6) ELISA Kits

Mouse (Murine) CD6 interaction partners

1. these data indicate that CD6 modulates the threshold for thymocyte selection and the generation and/or function of several peripheral T cell subpopulations, including T reg cells

2. results reveal an unexpected role of CD6 in the pathogenesis of intestinal IR-induced injury by regulating the self-renewal of B1a cells.

3. this analysis identified 65 proteins not associated before with the Zap70 (show ZAP70 ELISA Kits)-Lat (show LAT ELISA Kits)-SLP-76 (show LCP2 ELISA Kits) network and thus should provide cues for future functional experiments.

Human CD6 interaction partners

1. These data are consistent with a model in which bivalent recruitment of a GADS (show GRAP2 ELISA Kits)/SLP-76 (show LCP2 ELISA Kits) complex is required for costimulation by CD6.

2. Data indicate that the T cell-specific adaptor protein (TSAd) SH2 domain interacts with CD6 antigen and linker for activation of T cells (show LAT ELISA Kits) protein (LAT) phosphotyrosine (pTyr) peptides.

3. Results from recent genetic association studies provide evidence for a role of CD6 in multiple sclerosis and in rheumatoid arthritis pathogenesis. [review]

4. Study provides evidence on the role of CD6, a lymphocyte-specific surface receptor from to the ancient and highly conserved Scavenger Receptor Cysteine-Rich (SRCR) superfamily, as a pattern recognition receptor, and the functional consequences this may have on T cell activation and differentiation. [review]

5. Data show the multiple aspects that determine the nature of the signals transmitted via CD6 and the context that may define a dual role for this important T cell surface molecule (show CD8A ELISA Kits). [review]

6. Data show a role for extracellular and intracellular interactions of CD6 in lateral movement in response to T cell activation. [review]

7. The binding sites on CD6 and CD166 (show ALCAM ELISA Kits) have been characterized to show that a SNP in CD6 causes glycosylation that hinders the CD6/CD166 (show ALCAM ELISA Kits) interaction.

8. CD6 regulatory T cells are characterized by CD6 expression and FOXP3 (show FOXP3 ELISA Kits) expression.

9. interaction of Galectin-1 (show LGALS1 ELISA Kits) and -3 with CD6

10. upon T cell activation, SRSF1 (show SRSF1 ELISA Kits) becomes limiting, and its function in CD6 exon 5 splicing is countered by an increase in CD6 transcription, dependent on chromatin acetylation.