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Drug-resistance related protein, its expression is associated with the chemotherapy resistant and neoplastic phenotype.
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DNA demethylation is an important epigenetic mechanism that regulates the TRAG-3 tumor antigen in human tumors
As the TRAG-3 gene is located on Xq28, which is the same locus as the MAGE (show MAGEB10 Antibodies) gene family, we found a frequent synchronous expression pattern with TRAG-3 and MAGE-3 (show MAGEA3 Antibodies) in esophageal cancer.
TRAG-3-specific CD4+ T cells recognize in vitro not only peptide pulsed antigen presenting cells but also autologous dendritic cells loaded with the TRAG-3 protein.
Human VCX/Y, SPANX, and CSAG2 gene families together with the murine SPANX gene and the CYPT family may share a common ancestor.
TRAG3 was significantly higher in T24-L and T24-B than T24-P. TRAG3 gene expression is likely controlled by DNA methylation (show HELLS Antibodies) but not histone acetylation
Drug-resistance related protein, its expression is associated with the chemotherapy resistant and neoplastic phenotype. May also be linked to the malignant phenotype.
CSAG family, member 2
, CSAG family, member 3B
, chondrosarcoma associated gene 1
, cancer/testis antigen 24.2
, cancer/testis antigen family 24, member 2
, chondrosarcoma-associated gene 2/3 protein
, chondrosarcoma-associated gene 2/3 protein-like
, taxol resistance associated gene 3
, taxol-resistant-associated gene 3 protein