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Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Additionally we are shipping CELF6 Antibodies (32) and CELF6 Kits (12) and many more products for this protein.
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Analysis of common variants near the corresponding genes implicated the RNA binding protein (show PTBP1 Proteins) CELF6 in autism risk
CELF6 is a member of the CELF (show CEBPD Proteins) family of RNA-binding proteins that regulates muscle-specific (show EIF3K Proteins) splicing enhancer-dependent alternative splicing
Results suggest that disruption of CUG-BP, Elav-like factor 6 expression in hypothalamic nuclei may impact a variety of behaviors downstream of neuropeptide activity, while disruption in neuromodulatory transmitter expressing areas such as the ventral tegmental area, substantia nigra, raphe nuclei and locus coeruleus may have far-reaching influences on overall brain activity.
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
CUGBP Elav-like family member 6
, CUGBP, Elav-like family member 6
, Bruno -like 6, RNA binding protein
, CUG-BP and ETR-3 like factor 6
, CUG-BP- and ETR-3-like factor 6
, RNA-binding protein BRUNOL-6
, bruno-like 6, RNA binding protein
, bruno-like protein 6