anti-Calpain 6 (CAPN6) Antibodies

Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Additionally we are shipping Calpain 6 Kits (10) and Calpain 6 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CAPN6 827 Q9Y6Q1
CAPN6 12338 O35646
CAPN6 83685 O88501
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Top anti-Calpain 6 Antibodies at antibodies-online.com

Showing 10 out of 68 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB CAPN6 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CAPN6 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. CAPN6 Antibody (Center) western blot analysis in HL-60 cell line lysates (35µg/lane).This demonstrates the CAPN6 antibody detected the CAPN6 protein (arrow). 0.4 mL 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated ELISA, IHC, WB Western blot analysis of CAPN6 using NIH-3T3 whole cell lysates ABIN6279235 at 1/100 staining Mouse placenta tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL 11 to 14 Days
$419.83
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-CAPN6 / Calpain 6 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg 11 to 14 Days
$616.00
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Recombinant protein. 100 μg 13 to 16 Days
$350.00
Details
Human Rabbit Un-conjugated IHC (p), WB Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) Western blot analysis of CAPN6 in rat lung tissue lysate with CAPN6 antibody at (A) 0.5 and (B) 1 µg/ml. 50 μg 6 to 8 Days
$495.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.1 mg 4 to 8 Days
$522.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of human placenta, using CAPN6 antibody (ABIN5971957). 100 μL 11 to 16 Days
$426.40
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB   100 μg 15 to 19 Days
$527.03
Details
Human Rabbit Un-conjugated ELISA, FM, IHC, WB Immunofluorescence of CAPN6 Antibody Immunofluorescence Microscopy of CAPN6 antibody.   Tissue: Human lung cells.   Fixation:  0.5% PFA. Antigen retrieval:  not required. Primary antibody:  CAPN6 antibody  at 20 µg/mL  for 1 h at RT. Secondary antibody:  Fluorescein rabbit secondary antibody at 1:10,000 for 45 min at RT. Staining: CAPN6 as a red fluorescent signal. Western Blot of CAPN6 Antibody Western Blot of CAPN6 antibody.   Lane A:  Rat lung tissue lysate at 0.5 µg/mL.   Lane B:  Rat lung tissue lysate at 1 µg/mL. Load:  35 µg per lane. Secondary antibody:   Peroxidase rabbit secondary antibody at 1:10,000 for 45 min at RT. Block:  5% BLOTTO overnight at 4°C. Predicted/Observed size:  74.5 kDa,  ~75 kDa for CAPN6. 100 μg 1 to 2 Days
$394.90
Details

Top referenced anti-Calpain 6 Antibodies

  1. Human Polyclonal Calpain 6 Primary Antibody for IHC (fro), WB - ABIN549022 : Matena, Boehm, Dear: Genomic organization of mouse Capn5 and Capn6 genes confirms that they are a distinct calpain subfamily. in Genomics 1998 (PubMed)
    Show all 3 Pubmed References

More Antibodies against Calpain 6 Interaction Partners

Human Calpain 6 (CAPN6) interaction partners

  1. High CAPN6 expression is associated with liver cancer.

  2. CAPN6 promotes atherogenicity in inflamed macrophages by disturbing CWC22/EJC systems.

  3. syndecan-2 exerts its pro-apoptotic function through modulation of the endothelin-1/NFkappaB signaling and through downregulation of calpain-6.

  4. results indicated that calpain 6 supported tumorigenesis by inhibiting apoptosis and facilitating angiogenesis. To our knowledge, this result is the first evidence implicating calpain 6 in tumorigenesis

Mouse (Murine) Calpain 6 (CAPN6) interaction partners

  1. CAPN6 promotes atherogenicity in inflamed macrophages by disturbing CWC22/EJC systems.

  2. These results collectively showed that a loss of CAPN6 promotes skeletal muscle differentiation during both development and regeneration, suggesting a novel physiological function of CAPN6 as a suppressor of skeletal muscle differentiation.

  3. CAPN6 acts as a regulator of Rac1 and cell motility through interaction with GEF-H1.

  4. Capn6 promotes cytoskeletal organization and microtubule stability in osteoclasts.

  5. Capn6 is a microtubule-stabilizing protein expressed in embryonic tissues that may be involved in the regulation of microtubule dynamics and cytoskeletal organization.

Calpain 6 (CAPN6) Antigen Profile

Protein Summary

Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.

Gene names and symbols associated with anti-Calpain 6 (CAPN6) Antibodies

  • calpain 6 (CAPN6) antibody
  • calpain 6 (Capn6) antibody
  • CalpM antibody
  • CANPX antibody
  • CAPN6 antibody
  • CAPNX antibody
  • DJ914P14.1 antibody

Protein level used designations for anti-Calpain 6 (CAPN6) Antibodies

calpain 6 , calpain-6 , calpain-6-like , calpain-like protease X-linked , calpamodulin

GENE ID SPECIES
422341 Gallus gallus
465810 Pan troglodytes
492068 Canis lupus familiaris
539360 Bos taurus
100054264 Equus caballus
100348781 Oryctolagus cuniculus
100414757 Callithrix jacchus
100445314 Pongo abelii
100480750 Ailuropoda melanoleuca
100522971 Sus scrofa
100593880 Nomascus leucogenys
827 Homo sapiens
12338 Mus musculus
83685 Rattus norvegicus
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