anti-Cancer Susceptibility Candidate 3 (CASC3) Antibodies

The product of CASC3 is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). Additionally we are shipping Cancer Susceptibility Candidate 3 Proteins (5) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CASC3 22794 O15234
CASC3 192160 Q8K3W3
CASC3 259170 Q8K3X0
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Top anti-Cancer Susceptibility Candidate 3 Antibodies at antibodies-online.com

Showing 10 out of 98 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CASC3 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Positive Control: ACHN cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-CASC3 Antibody (Y181) (ABIN391402) in NCI-H460 cell line lysates (35 µg/lane). CASC3(arrow) was detected using the purified polyclonal antibody (1:60dilution). Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with CASC3 Antibody (Y181) (ABIN391402), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with CASC3 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Western blot analysis of anti-CASC3 Antibody in NCI-H460 cell line lysates (35 µg/lane). CASC3 (arrow) was detected using the purified Pab (1:60 dilution). 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with CASC3 Antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Western blot analysis of CASC3 (arrow) using rabbit polyclonal CASC3 Antibody (Mouse C-term) . 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the CASC3 gene (Lane 2) (Origene Technologies). 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of CASC3 (arrow) using rabbit polyclonal CASC3 Antibody (Mouse C-term) (ABIN391401). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the CASC3 gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with CASC3 Antibody (C-term) (ABIN391401), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated IHC (p), IP, IHC Immunohistochemistry-Paraffin: CASC3 Antibody [NBP1-30321] - Human ovarian carcinoma. Antibody used at a dilution of 1:1000 (1ug/ml). 100 μL Log in to see 7 to 9 Days
$559.35
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 16 Days
$366.77
Details
Human Rabbit Un-conjugated IHC (p), WB Western Blot at 1:1000 dilution + NCI-H460 whole cell lysate Lysates/proteins at 20 ug per lane. Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with CASC3 Antibody (Y181) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated WB CASC3 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 9 to 11 Days
$473.93
Details

Top referenced anti-Cancer Susceptibility Candidate 3 Antibodies

  1. Human Polyclonal CASC3 Primary Antibody for ELISA, WB - ABIN544021 : Degot, Régnier, Wendling, Chenard, Rio, Tomasetto: Metastatic Lymph Node 51, a novel nucleo-cytoplasmic protein overexpressed in breast cancer. in Oncogene 2002 (PubMed)
    Show all 2 Pubmed References

More Antibodies against Cancer Susceptibility Candidate 3 Interaction Partners

Human Cancer Susceptibility Candidate 3 (CASC3) interaction partners

  1. High CASC3 expression is associated with hepatocellular carcinoma.

  2. MLN51, alone or as part of the EJC, interacts directly with the pivotal eukaryotic translation initiation factor eIF3

  3. MLN51 is a key factor in fibroblast-like synoviocyte hyperplasia of rheumatoid arthritis patients.

  4. data demonstrate that metastatic lymph node(MLN)51 protein associates with exon junction complex in the nucleus and remains stably associated with messenger RNA in the cytoplasm

  5. crystal structure of a tetrameric exon junction core complex containing the DEAD-box adenosine triphosphatase eukaryotic initiation factor 4AIII bound to an ATP analog, MAGOH, Y14, a fragment of MLN51, and a polyuracil mRNA mimic

  6. MLN51 is recruited into cytoplasmic aggregates known as stress granules (SGs) together with the SG-resident proteins.

Mouse (Murine) Cancer Susceptibility Candidate 3 (CASC3) interaction partners

  1. data suggest that the mRNA transport machinery is conserved during evolution, and that mammalian Btz is an additional component of the dendritic ribonucleoprotein particles in hippocampal neurons

Cancer Susceptibility Candidate 3 (CASC3) Antigen Profile

Protein Summary

The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles.

Gene names and symbols associated with CASC3

  • cancer susceptibility 3 (CASC3) antibody
  • cancer susceptibility candidate 3 (Casc3) antibody
  • cancer susceptibility 3 (Casc3) antibody
  • cancer susceptibility 3 (casc3) antibody
  • protein CASC3 (casc3) antibody
  • cancer susceptibility 3 S homeolog (casc3.S) antibody
  • cancer susceptibility candidate 3 (casc3) antibody
  • barentsz antibody
  • btz antibody
  • CASC3 antibody
  • mln51 antibody
  • StMLN51 antibody
  • XlMLN51 antibody

Protein level used designations for CASC3

MLN 51 , barentsz , cancer susceptibility candidate gene 3 protein , metastatic lymph node 51 , metastatic lymph node gene 51 protein , protein CASC3 , protein barentsz , Barentsz , MLN 51 homolog , cancer susceptibility candidate gene 3 protein homolog , mBtz , metastatic lymph node gene 51 protein homolog , barentsz protein , cancer susceptibility candidate 3 , Cancer susceptibility candidate gene 3 protein homolog , Metastatic lymph node protein 51 homolog , Protein MLN 51 homolog , drMLN51 , metastatic lymph node protein 51 homolog , protein MLN 51 homolog

GENE ID SPECIES
22794 Homo sapiens
192160 Mus musculus
259170 Rattus norvegicus
426135 Gallus gallus
454646 Pan troglodytes
480528 Canis lupus familiaris
503560 Xenopus (Silurana) tropicalis
531673 Bos taurus
699712 Macaca mulatta
100189566 Xenopus laevis
100358381 Oryctolagus cuniculus
398567 Xenopus laevis
403025 Danio rerio
100727378 Cavia porcellus
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