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Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). Additionally we are shipping CNPY2 Antibodies (53) and CNPY2 Proteins (9) and many more products for this protein.
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Human CNPY2 ELISA Kit for Sandwich ELISA - ABIN1169616
Yan, Gong, Zhai, Feng, Wu, He, Guo, Wang, Guo, Xie, Li: Decreasing CNPY2 Expression Diminishes Colorectal Tumor Growth and Development through Activation of p53 Pathway. in The American journal of pathology 2016
Free CNPY2 then engages protein kinase (show CDK7 ELISA Kits) R-like endoplasmic reticulum kinase (PERK (show EIF2AK3 ELISA Kits)) to induce expression of the transcription factor C/EBP homologous protein (CHOP (show DDIT3 ELISA Kits)), thereby initiating the unfolded protein response.
CNPY2 may play a critical role in colorectal cancer development by enhancing cell proliferation, migration, and angiogenesis and by inhibiting apoptosis through negative regulation of the p53 (show TP53 ELISA Kits) pathway
The data demonstrate CNPY2 is widely distributed in tissues and suggest the protein has biological functions that have yet to be identified.
CNPY2 is a HIF-1alpha (show HIF1A ELISA Kits)-regulated, secreted angiogenic growth factor that promotes smooth muscle cell migration, proliferation, and tissue revascularization.
Overexpression of CNPY2 can activate the AKT (show AKT1 ELISA Kits)/GSK3beta pathway, which leads to the inactivation of GSK-3beta. The inactivation of GSK-3beta increases the level of Snail (show SNAI1 ELISA Kits), and then decreases the expression of E-cadherin (show CDH1 ELISA Kits) to promote EMT (show ITK ELISA Kits).
CNPY2 can serve as a therapeutic target to promote the effect of chemotherapy in non-small cell lung cancer.
CNPY2 isoform2 represents as a novel and valuable prognostic indicator for colorectal cancer patients.
These findings suggested that CNPY2 promoted cancer cell growth in renal cell carcinoma (show MOK ELISA Kits) cells through regulating TP53 (show TP53 ELISA Kits) gene expression.
Our results are consistent with an important role of FGF21 (show FGF21 ELISA Kits) and Cnpy2/Msap in the regulation of LDLRs in cultured cells.
MSAP is a novel MIR-interacting protein that enhances neurite outgrowth and increases myosin regulatory light chain in fetal and adult brain.
Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation (By similarity).
MIR-interacting saposin-like protein
, protein canopy homolog 2
, putative secreted protein ZSIG9
, transmembrane protein 4
, canopy 2 homolog
, putative secreted protein Zsig9