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The protein encoded by CA6 is one of several isozymes of carbonic anhydrase. Additionally we are shipping Carbonic Anhydrase VI Kits (18) and Carbonic Anhydrase VI Proteins (12) and many more products for this protein.
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Molecular cloning of a full-length cDNA of carbonic anhydrase VI and its expression in mutliple tissues are reported.
he altered biological processes included antigen transport by M-cells, potassium transport, muscle contraction, and thyroid hormone (show PTH Antibodies) synthesis. Immunohistochemical staining confirmed the absence of CA VI in the submandibular gland of Car6 (-/-) mice
knockout mouse model confirms that CA VI is involved in bitter taste perception. CA VI may be one of the factors which contribute to avoidance of bitter, potentially harmful, substances.
The generation of Car6 (-/-) mice and examination of the effects of CAVI deficiency on gene transcription have revealed several affected clusters of biological processes, which implicate CAVI in catabolic processes and the immune system response.
Car4, Car6, and Car12 showed moderate expression levels in the mouse harderian gland.
expression of Car6 significantly decreased in enamel organs from Mmp20 (show MMP20 Antibodies)(-/-) mice. A feedback mechanism regulates ion-responsive gene expression during enamel development.
genetic association studies in population of elderly women in Poland: Data suggest that SNPs in TAS2R38 (show TAS2R38 Antibodies) (rs713598, rs1726866, rs10246939) and an SNP in CA6 (rs2274333) are associated with intake of and preferences for some foods (coffee and white cabbage) among the population studied. (TAS2R38 (show TAS2R38 Antibodies) = taste receptor type 2 member 38 (show TAS2R38 Antibodies); CA6 = carbonic anhydrase VI)
Results found that the CA VI gene polymorphism rs2274327 showed no correlation between salivary parameters and dental-oral health status in Eastern Anatolian Turkish children.
dental plaque amount, lactobacilli count, age, and saliva (show RAG1AP1 Antibodies) buffer capacity, as well as CA6 (T55M) gene polymorphism, explained total of 87.8% of variations in DMFT scores.
We also found that the haplotype (ACA) (rs2274328, rs17032907 and rs11576766)of the carbonic anhydrase VI was associated with a low number of decayed, missing, and filled teeth index with an odds ratio (95% confidence interval) of 0.635 (0.440-0.918).
Study showed that PROP (6-n-propylthiouracil) bitterness was due to TAS2R38 (show TAS2R38 Antibodies) diplotypes, whereas the density of fungiform papillae was more closely associated with gustin genotypes
results suggest that polymorphisms in the CA6 gene are associated with the concentrations of secreted CA VI.
The rs2274333 polymorphism of the gustin gene affects PROP sensitivity.
The aim of this study was to investigate carbonic anhydrase (CA) VI Exon 2 single nucleotide polymorphism (SNP) and its possible association with salivary parameters in type 2 diabetic patients compared to healthy adults.
The 1.9A crystal structure of the human CA VI catalytic domain reveals a prototypical mammalian CA fold, and a novel dimeric arrangement as compared to previously-reported CA structures.
The data of this study showed how the combination of the TAS2R38 (show TAS2R38 Antibodies) and gustin gene genotypes modulate PROP phenotype.
Bovine mammary epithelial cells synthesize and secrete CA VI in colostrum at higher concentration than in normal milk, implying its role to compensate for low CA VI secretion in neonatal calves.
Date suggest that the localisation of carbonic anhydrase VI (CA-VI) indicates that it may play a specialised role in the kidney.
The protein encoded by this gene is one of several isozymes of carbonic anhydrase. This protein is found only in salivary glands and saliva and protein may play a role in the reversible hydratation of carbon dioxide though its function in saliva is unknown.
carbonic anhydrase VI
, carbonic anhydrase 6
, carbonate dehydratase VI
, salivary carbonic anhydrase
, secreted carbonic anhydrase