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The 83 kDa subunit binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation.
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Human Polyclonal CPN2 Primary Antibody for IHC, IHC (p) - ABIN4300256
Kato, Nicholson, Neiman, Rantalainen, Holmes, Barrett, Uhlén, Nilsson, Spector, Schwenk: Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model. in Proteome science 2011
Real-time PCR and western blotting show the following CPN2 expression: minimal in MDA-MB-468 cells but obvious in MDA-MB-231 and MCF7 cells. MDA-MB-231 breast cancer cell lines were selected for the control group and CPN2 was knocked out for the experimental group.
The 83 kDa subunit binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation. Under some circumstances it may be an allosteric modifier of the catalytic subunit.
carboxypeptidase N, polypeptide 2
, carboxypeptidase N, polypeptide 2, 83kD
, carboxypeptidase N subunit 2
, carboxypeptidase N 83 kDa chain
, arginine carboxypeptidase (carboxypeptidase N)
, carboxypeptidase N large subunit
, carboxypeptidase N regulatory subunit
, carboxypeptidase N, polypeptide 2 homolog