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Members of the CEACAM subfamily, including CEACAM5, belong to the CEA gene family. Additionally we are shipping CEACAM5 Antibodies (464) and CEACAM5 Kits (11) and many more products for this protein.
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The detection of TK1 (show TK1 Proteins) combined with that of cytokeratin-19 (show KRT19 Proteins) fragment (CYFRA21-1), CEA or NSE (show ENO2 Proteins) increased the diagnostic value of TK1 (show TK1 Proteins) for lung squamous cell carcinoma, adenocarcinoma and small cell lung cancer, respectively.
Helicobacter pylori HopQ binds the amino-terminal IgV-like domain of human CEACAM1 (show CEACAM1 Proteins), CEACAM3 (show CEACAM3 Proteins), CEACAM5 or CEACAM6 proteins, thereby enabling translocation of the major pathogenicity factor CagA (show S100A8 Proteins) into host cells.
Here, the authors identify members of the carcinoembryonic antigen-related cell adhesion molecule (show MCAM Proteins) (CEACAM) family as receptors of Helicobacter pylori and show that HopQ is the surface-exposed adhesin that specifically binds human CEACAM1 (show CEACAM1 Proteins), CEACAM3 (show CEACAM3 Proteins), CEACAM5 and CEACAM6.
Combining the targets E-cadherin (show CDH1 Proteins), epithelial membrane antigen (EMA (show ETFA Proteins)), human epidermal growth receptor type 2 (Her2/neu (show ERBB2 Proteins)), carcinoembryonic antigen (CEA) resulted in nearly 100% detection of ductal ovarian metastases, whereas the combination of EMA (show ETFA Proteins), Her2/neu (show ERBB2 Proteins) and epithelial cell adhesion molecule (EpCAM (show EPCAM Proteins)) was most suitable to detect lobular ovarian metastases.
In patients with non-small-cell lung cancer treated with nivolumab, worse pretreatment performance status, and higher carcinoembryonic antigen were associated with inferior progression-free survival.
To examine the relation of carcinoembryonic antigen (CEA) response with tumor response and survival in patients with (K)RAS (show HRAS Proteins) wild-type metastatic colorectal cancer receiving first-line chemotherapy in the FIRE-3 trial comparing FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab
This is the first population-based investigation of a large cohort of exclusively stage I rectal cancer patients providing compelling evidence that elevated preoperative CEA level is a strong predictor of worse overall and cancer-specific survival.
Elevated levels of systemic IFNgamma and IL-6 (show IL6 Proteins) implied that the CEACAM5-specific T cells had undergone immune activation in vivo but only in patients receiving high-intensity pre-conditioning.
Combination of the two tumor markers, CEA and CYFRA21-1, is a predictive and prognostic marker of docetaxel monotherapy for previously treated NSCLC patients
Patients with CEA-High stage I NSCLC have a higher risk of regional or systemic relapse and should be followed-up carefully.
a new mechanistic insight into how the CEA (show CEA Proteins) IgV-like N domain participates in cellular events that can have a macroscopic impact in terms of cancer progression and metastasis.
Members of the CEACAM subfamily, including CEACAM5, belong to the CEA gene family. For general information on the CEA gene family, see CEACAM1 (MIM 109770).
carcinoembryonic antigen-related cell adhesion molecule 5
, carcinoembryonic antigen
, carcinoembryonic antigen-related cell adhesion molecule 5-like
, CEA-related cell adhesion molecule 20
, meconium antigen 100
, pregnancy-specific glycoprotein 30