anti-Casein beta (CSN2) Antibodies

expression is induced by pseudophosphorylated prolactin in mammary gland [RGD, Feb 2006].. Additionally we are shipping CSN2 Kits (37) and CSN2 Proteins (22) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CSN2 1447 P05814
CSN2 12991 P10598
CSN2 29173  
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Top anti-CSN2 Antibodies at antibodies-online.com

Showing 10 out of 75 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB CSN2 Antibody (N-term) (ABIN656593) western blot analysis in MDA-MB435 cell line lysates (35 µg/lane). This demonstrates the CSN2 antibody detected the CSN2 protein (arrow). Anti-CSN2 Antibody (N-term) at 1:1000 dilution + SK-BR-3 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 25 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Dilution: 1:1000 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated EIA, WB CSN2 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35µg/lane).This demonstrates the CSN2 antibody detected the CSN2 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Cow Rabbit Un-conjugated IF (p), IHC (p), WB Bocine mammary tissue lysates probed with Rabbit Anti-Beta-casein Polyclonal Antibody, Unconjugated (ABIN1385095) at 1:300 overnight at 4 °C. Followed by a conjugated secondary antibody  at 1:5000 for 90 min at 37 °C. 100 μL Log in to see 3 to 7 Days
$329.45
Details
Human Rabbit Un-conjugated ICC, IHC, WB DAB staining on IHC-P; Samples: Human Breast cancer Tissue 100 μg Log in to see 13 to 16 Days
$350.00
Details
Human Mouse Un-conjugated IHC, WB   0.1 mg Log in to see 7 to 9 Days
$418.10
Details
Sheep Rabbit Un-conjugated IF (p), IHC (p), WB Lane 1: sheep non-fat milk Lane 2: bovine non-fat milk probed with Anti Beta-casein Polyclonal Antibody, Unconjugated (ABIN668976) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 23kD. Observed band size: 23kD 100 μL Log in to see 3 to 7 Days
$317.90
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: beta Casein Antibody [NBP1-88188] - Staining of human cerebral cortex shows moderate nuclear positivity in neuronal cells. Immunohistochemistry-Paraffin: beta Casein Antibody  - Staining of human lactating breast shows strong cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using CSN2 antibody. 200 μL Log in to see 12 to 14 Days
$438.90
Details
Cow Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$406.45
Details
Cow Rabbit Cy5 IF (p)   100 μL Log in to see 14 to 21 Days
$428.45
Details

Top referenced anti-CSN2 Antibodies

  1. Cow (Bovine) Polyclonal CSN2 Primary Antibody for IF (p), IHC (p) - ABIN1385095 : He, McMahon, McKeon, Brandon: Development of a novel immuno-PCR assay for detection of ricin in ground beef, liquid chicken egg, and milk. in Journal of food protection 2010 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal CSN2 Primary Antibody for IHC, WB - ABIN251165 : Chiba, Kimura, Takahashi, Morimoto, Sanbe, Ueda, Kudo: Serotonin suppresses β-casein expression via inhibition of the signal transducer and activator of transcription 5 (STAT5) protein phosphorylation in human mammary epithelial cells MCF-12A. in Biological & pharmaceutical bulletin 2014 (PubMed)
    Show all 2 Pubmed References

More Antibodies against CSN2 Interaction Partners

Human Casein beta (CSN2) interaction partners

  1. Data suggest that neurogenesis in neuronal stem cells is differentially affected by human and bovine beta-casein-derived opioid peptides BCM7 and BCM9; such neurogenic changes are accompanied by changes in glutathione/glutathione disulfide ratio and in S-adenosylmethionine/S-adenosylhomocysteine ratio, indicative of changes in redox and methylation states (including DNA methylation).

  2. Exogenous 5-HT decreased beta-casein expression in MCF-12A human mammary epithelial cells and was responsible for inhibiting phosphorylation of STAT5, resulting in a decline in lactational function.

  3. The acidic fragment of human Abeta (Abeta1-11) and a phosphorylated fragment of beta-Casein induced tau fibrillization in vitro.

  4. Milk congestion gives rise to higher levels of beta-casomorphin-8 in milk and plasma than in lactating women without problems.

  5. derivatives of peptide fragment (54-59) exhibit immunosuppressant activity

  6. New functions of lactoferrin and beta-casein in mammalian milk as cysteine protease inhibitors. They might play a role in antiseptic and antiinfectious functions due to cysteine protease inhibition of bacteria and viruses.

  7. The RCM-kappa does form concentration-dependent micelles. Also, beta-CN phosphorylation level influences micelle formation. Complexes were low-temperature reversible and RCM-kappa fibrils were seen.

  8. a negative cross talk between PR and Stat5a/GR may contribute to the physiological role of progesterone to repress lactogenic hormone induction of the beta-casein gene

Cow (Bovine) Casein beta (CSN2) interaction partners

  1. Data suggest that neurogenesis in neuronal stem cells is differentially affected by human and bovine beta-casein-derived opioid peptides BCM7 and BCM9; such neurogenic changes are accompanied by changes in glutathione/glutathione disulfide ratio and in S-adenosylmethionine/S-adenosylhomocysteine ratio, indicative of changes in redox and methylation states (including DNA methylation).

  2. Data suggest that the resulting knock-in cells and blastocysts could be used for the production of transgenic cattle that express human fibroblast growth factor 2 (hFGF2) within the bovine beta-casein gene locus.

  3. Translation attenuation via 3' terminal codon usage in bovine mRNA is responsible for the difference in alpha-S2- and beta-casein profile in milk.

  4. This suggests a superiority of allele A2 (0.7072) which does not produce BCM-7, and thus is safe for human consumption. The expected homozygosity for gene CSN2 is in the population stated a slight increase in homozygosity

  5. chaperone-like activity of bovine beta-casein (beta-CN) against thermal denaturation and aggregation processes of bovine carbonic anhydrase

  6. The obtained results lead to the following conclusion: the highest amount of beta-casomorphin-7 released from the hydrolyzed and processed milk is related to the beta-casein A1 allele, irrespective of a lactation period.

  7. These results demonstrate the enhanced chaperone activity of modified beta-casein and its protective effects on lysozyme refolding.

  8. Effects of beta-kappa-casein (CSN2-CSN3) haplotypes and BLG genotypes on yields were weak or trivial.

  9. New functions of lactoferrin and beta-casein in mammalian milk as cysteine protease inhibitors. They might play a role in antiseptic and antiinfectious functions due to cysteine protease inhibition of bacteria and viruses.

  10. bovine beta-casein heat and alkaline denaturation analysis

  11. Data show that the tail peptide beta-casein-(f193-209) is important in maintaining the hydrophobic core of beta-casein.

  12. potential influence of beta-casein variants on human health [review]

  13. The effect of lactoferrin on beta-casein and kappa-casein mRNA expression in mammospheres while silencing of LTF increased casein mRNA expression.

  14. Substitution effects of paternal CSN2alpha(s1) allele versus CSN2alpha(s2) allele on protein yield deviations (YDs) are significant, whereas their effects on milk and fat YDs are not.

  15. characterize at high-resolution the CSN2 micelles' shape, dimensions, and aggregation numbers and to determine how these properties are affected by temperature between 1 and 40 degrees C.

  16. In heterozygotes, beta-casein A and beta-lactoglobulin A were found at higher concentrations in milk compared with the variant encoded by the alternative allele whereas kappa-casein A and B variants were found at similar concentrations in AB heterozygotes

  17. Genetic variation of CSN2 is consistently associated with both higher protein and milk yields.

  18. Dimerization of C208 beta-CN with two distal hydrophilic domains considerably improved its chaperone-like activity in comparison with its monomeric form.

  19. Serotonin suppressed beta-casein mRNA expression in lactogen-treated primary bovine mammary epithelial cell cultures.

  20. confirmed a possible role of C-terminal hydrophobic domain in the immunoreactivity profile of native beta-casein

Mouse (Murine) Casein beta (CSN2) interaction partners

  1. These results indicate that PRL, EGF and glucocorticoids have distinct roles in the establishment of beta-casein secretion pathway.

  2. Dexamethasone signaling upregulates Claudin-3 and -4 without beta-casein expression. Prolactin and dexamethasone signaling synergistically upregulate beta-casein expression.

  3. octamer-binding transcription factor-1 may serve as a master regulator that facilitates the DNA binding of both signal transducer and activator of transcription 5 and glucocorticoid receptor in hormone-induced beta-casein expression

  4. It was found that both IGF-1 and IGF-2 activate the expression of milk protein beta-casein in the presence of prolactin and hydrocortisone. It was found that beta-casein expression is accompanied by cyclin D1 coexpression.

  5. mammary cells express beta-casein in response to prolactin in a pathway that involves gap junction intracellular communication and OCT-1 and is independent of STAT5 nuclear translocation

  6. Progesterone receptor directly inhibits beta-casein gene transcription in mammary epithelial cells through promoting promoter and enhancer repressive chromatin modifications

  7. Our data thus suggest that the degradation of beta-casein occurs via the microautophagic pathway.

  8. In vitro expression of recombinant basement membrane-mediated beta-casein gene can be controlled pharmacologically by histone deacetylase inhibitors or by overexpression of a histone acetylase enzyme.

  9. Elevated levels of beta-casein gene expression were found in transgenic mice with stat5 during late pregnancy and lactation.

  10. the first intron of the murine beta-casein gene contains a functional promoter, and beta-casein has intronic enhancer elements

  11. Liver-enriched inhibitory protein plays critical role in mediating TNF-induced down-regulation of the beta-casein gene.

  12. The ubiquitous Oct-1 transcription factor may be involved in hormonally regulated, tissue-specific beta-casein gene expression.

  13. a negative cross talk between PR and Stat5a/GR may contribute to the physiological role of progesterone to repress lactogenic hormone induction of the beta-casein gene

  14. These results demonstrate that TGF-beta abrogates prolactin-stimulated beta-casein gene expression in mammary epithelial cells through, at least in part, a Smad3-dependent mechanism.

  15. the interaction of glucocorticoid receptor with Oct-1 on the beta-casein gene promoter

  16. The developmental regulation of DNA looping between the beta-casein regulatory regions was observed in lactating but not in virgin mouse mammary glands.

Goat Casein beta (CSN2) interaction partners

  1. CSN2 polymorphisms are potential markers for milk production in goats.

  2. the nucleotide C at position 1311 negatively affects the promoter activity of the CSN2 gene; the SNP g.1311T>C associated with the absence of beta-casein in milk

  3. findings demonstrate that the proximal -300 bp of CSN2 promoter containing the STAT5a binding site (-102 to -82) is the response element for lactogenic hormone stimulation; also intron 1 may be required for tissue or developmental stage-specific expression in mammary gland

  4. Data show that the presence of beta-casein (CSN2) transcripts was detected in all samples, including cells originating from non-lactating goat.

Horse (Equine) Casein beta (CSN2) interaction partners

  1. Results describe the primary structure of a low-molecular weight multiphosphorylated variant of beta-casein in equine milk.

Pig (Porcine) Casein beta (CSN2) interaction partners

  1. The effects of prolactin receptor and beta-casein genotype on the nutritive value of sow milk are reported.

  2. The authors describe five novel missense single nucleotide polymorphisms in the CSN2 and CSN3 genes that have large differences in allele frequencies among commercial pig breeds.

  3. Transcription of porcine CSN2 is regulated by lactogenic signals via the STAT5 site (-102bp to -84bp) and intron 1.

CSN2 Antigen Profile

Protein Summary

expression is induced by pseudophosphorylated prolactin in mammary gland

Gene names and symbols associated with anti-Casein beta (CSN2) Antibodies

  • casein beta (CSN2) antibody
  • casein beta (Csn2) antibody
  • CASB antibody
  • Csnb antibody

Protein level used designations for anti-Casein beta (CSN2) Antibodies

beta-casein , beta casein B , milk protein , beta casein , pre-beta-casein (AA -15 to 213)

GENE ID SPECIES
1447 Homo sapiens
281099 Bos taurus
443391 Ovis aries
12991 Mus musculus
29173 Rattus norvegicus
100860784 Capra hircus
100033903 Equus caballus
404088 Sus scrofa
100009539 Oryctolagus cuniculus
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