anti-Catenin, beta Interacting Protein 1 (CTNNBIP1) Antibodies

The protein encoded by CTNNBIP1 binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. Additionally we are shipping CTNNBIP1 Proteins (15) and CTNNBIP1 Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CTNNBIP1 67087 Q9JJN6
CTNNBIP1 56998 Q9NSA3
CTNNBIP1 503000  
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Top anti-CTNNBIP1 Antibodies at antibodies-online.com

Showing 10 out of 58 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated IF (p), IHC (p) Paraformaldehyde-fixed, paraffin embedded mouse brain Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes Blocking buffer (normal goat serum) at 37°C for 30min Antibody incubation with CTNNBIP1 Polyclonal Antibody, Unconjugated  at 1:400 overnight at 4°C, DAB staining. 100 μL 3 to 7 Days
$329.45
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. DAB staining on IHC-P; Samples: Human Liver Tissue. 100 μg 13 to 16 Days
$350.00
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Figure.DAB staining on IHC-P. Samples: Mouse Tissue 100 μg 13 to 16 Days
$360.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (34.65 KDa) . 200 μL 11 to 12 Days
$440.00
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL 14 to 21 Days
$428.45
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of mouse heart, using CTNNBIP1 antibody. 100 μL 11 to 13 Days
$366.77
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (35.02 KDa) . 50 μL 11 to 12 Days
$305.71
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL 14 to 21 Days
$428.45
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL 14 to 21 Days
$428.45
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL 14 to 21 Days
$428.45
Details

Top referenced anti-CTNNBIP1 Antibodies

  1. Human Polyclonal CTNNBIP1 Primary Antibody for IHC (p), WB - ABIN546113 : Marin, Bustos, Cesaro, Meggio, Pagano, Antonelli, Allende, Pinna, Allende: A noncanonical sequence phosphorylated by casein kinase 1 in beta-catenin may play a role in casein kinase 1 targeting of important signaling proteins. in Proceedings of the National Academy of Sciences of the United States of America 2003 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal CTNNBIP1 Primary Antibody for WB - ABIN546115 : Sakanaka: Phosphorylation and regulation of beta-catenin by casein kinase I epsilon. in Journal of biochemistry 2002 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal CTNNBIP1 Primary Antibody for IHC (p), WB - ABIN546114 : Xing, Clements, Kimelman, Xu: Crystal structure of a beta-catenin/axin complex suggests a mechanism for the beta-catenin destruction complex. in Genes & development 2003 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal CTNNBIP1 Primary Antibody for IF (p), IHC (p) - ABIN753748 : Qi, Chen, Cheng, Huang, Xiang, Li, Long, Zhu: Targeting the Wnt-Regulatory Protein CTNNBIP1 by micro RNA-214 Enhances the Stemness and Self-Renewal of Cancer Stem-Like Cells in Lung Adenocarcinomas. in Stem cells (Dayton, Ohio) 2015 (PubMed)

More Antibodies against CTNNBIP1 Interaction Partners

Mouse (Murine) Catenin, beta Interacting Protein 1 (CTNNBIP1) interaction partners

  1. miR-215-5p is a negative regulator of adipocyte differentiation through post-transcriptional regulation of FNDC3B and CTNNBIP1 during early adipogenesis

  2. miR-29b plays a pivotal role in fetal mouse neurogenesis by regulating ICAT-mediated Wnt/beta-catenin signaling.

  3. Mechanistic studies revealed that CTNNBIP1 suppresses Wnt/beta-catenin signaling and that miR-215 promotes beta-catenin activation and upregulates alpha-SMA and fibronectin expression in TGF-beta1-treated MMCs by targeting CTNNBIP1

  4. Overexpression of Icat induces G(2) arrest and cell death in tumor cell mutants for adenomatous polyposis coli, beta-catenin, or Axin.

  5. ICAT plays an important role in the anteriorization of neural cells by inhibiting the posteriorizing activity of Wnt signaling

  6. These results suggest that the loss of ICAT gene function causes the arrest of UB branching and the apoptotic death of MM cells, resulting in renal agenesis.

  7. Inhibition of beta-catenin signaling in articular chondrocytes causes increased cell apoptosis and articular cartilage destruction in Col2a1-ICAT- transgenic mice.

Human Catenin, beta Interacting Protein 1 (CTNNBIP1) interaction partners

  1. Using ICAT as a tool to disengage beta-catenin-mediated APC-Axin interaction, we demonstrate that Wnt quickly inhibits the direct interaction between APC and Axin

  2. Alterations (deletion/methylation/mutation/expression) of MCC and CTNNBIP1 were analyzed in breast cancer patients (N=120) followed by expression/mutation analysis of beta-catenin. The alterations of MCC/CTNNBIP1 showed significant correlation with increased nuclear beta-catenin/p-beta-catenin(Y654) expression.

  3. CircRNA_102171 interacted with CTNNBIP1 to block its interaction with the beta-catenin/TCF3/TCF4/LEF1 complex, leading to activation of Wnt/beta-catenin pathway.

  4. Data demonstrated that ICAT was highly expressed in cervical cancer tissues and had a role in control of epithelial-mesenchymal transition (EMT) in cervical cancer cells. Its overexpression promoted cell proliferation, migration, invasion and resulted in EMT by disrupting the stability of E-cadherin/betacatenin complex.

  5. Low PLD1 expression and high ICAT expression were significantly associated with increased survival in colorectal cancer patients.

  6. The present work aims to investigate the relationship between the expression of AEG-1(astrocyte elevated gene-1), b-FGF(basic-fibroblast growth factor), beta-catenin, Ki-67, TNF-alpha (tumor necrosis factor-alfa) other prognostic parameters in DC (Ductal Carcinomas) and ductal intraepithelial neoplasm. We found a relationship between these factors.

  7. Overexpression of ICAT promoted Caski cells' proliferation, arrested the cell cycle in the S phase and enhanced cell migration. Conclusion Overexpression of ICAT can promote the proliferation and migration of Caski cervical cancer cells.

  8. Somatic mutation of beta-catenin (CTNNB1) is known to be crucial for Wilms tumor development in up to 15% of cases.

  9. CTNNBIP1 expression correlated with longer overall survival in LAC patients. This study reveals that miR-214 plays a critical role in CSLC self-renewal and stemness by targeting CTNNBIP1.

  10. Data show that microRNA miR-215 activates beta-catenin pathways by decreasing catenin beta interacting protein 1 (CTNNBIP1)expression in gliomas.

  11. Simultaneous silencing of beta-catenin and STAT3 synergistically induces apoptosis and inhibits cell proliferation in HepG2 liver cancer cells.

  12. Finally, pro-incubation with idebenone inhibited mitochondrial dysfunction induced by oxLDL through the mitochondrial-dependent apoptotic pathway and GSK3beta/beta-catenin signalling pathways.

  13. A potent beta-catenin inhibitor, ICAT/CTNNBIP1 was a direct target of miR-424-5p.

  14. Particulate matter (PM10) downregulates E-Cadherin/beta-Catenin expression.

  15. A statistically significant lapatinib- and gefitinib-induced repression of cyclin D1, MMP9 and beta-catenin in CERV196 cells.

  16. Nuclear YAP and cytoplasmic beta-catenin play important roles in carcinogenesis.

  17. review of control of cell fate and proliferation in colon cancer

  18. miR-603 regulates glioma development via Wnt-beta-cateninn signaling pathway and its WIF1 and CTNNBIP1 targets.

  19. These results indicate that beta-catenin translation is initiated via the IRES and this is regulated by PTX, suggesting that regulation of the IRES-dependent translation of beta-catenin may be involved in the cancer cell response to PTX treatment.

  20. ICAT may serve as a tumor-suppressor in human glioma.

CTNNBIP1 Antigen Profile

Protein Summary

The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with CTNNBIP1

  • catenin, beta interacting protein 1 (ctnnbip1) antibody
  • catenin beta interacting protein 1 L homeolog (ctnnbip1.L) antibody
  • catenin beta interacting protein 1 S homeolog (ctnnbip1.S) antibody
  • catenin beta interacting protein 1 (ctnnbip1) antibody
  • catenin, beta interacting protein 1 (CTNNBIP1) antibody
  • catenin beta interacting protein 1 (CTNNBIP1) antibody
  • catenin beta interacting protein 1 (Ctnnbip1) antibody
  • catenin, beta-interacting protein 1 (Ctnnbip1) antibody
  • 1110008O09Rik antibody
  • 2310001I19Rik antibody
  • AW457332 antibody
  • catnbip1 antibody
  • CTNNBIP1 antibody
  • ctnnbip1a antibody
  • ctnnbip1b antibody
  • fa95e12 antibody
  • Icat antibody
  • wu:fa95e12 antibody

Protein level used designations for CTNNBIP1

beta-catenin-interacting protein , beta-catenin-interacting protein 1 , catenin, beta interacting protein 1 a , catenin beta interacting protein 1 b , catenin, beta interacting protein 1 , inhibitor of beta-catenin and Tcf-4 , beta-catenin-interacting protein ICAT

GENE ID SPECIES
58117 Danio rerio
399114 Xenopus laevis
446455 Xenopus laevis
493465 Xenopus (Silurana) tropicalis
608589 Canis lupus familiaris
712257 Macaca mulatta
749394 Pan troglodytes
67087 Mus musculus
56998 Homo sapiens
771460 Gallus gallus
614630 Bos taurus
503000 Rattus norvegicus
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