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anti-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase Antibodies

56 results:

anti-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (AA 103-130) antibody Primary Antibody

CBLB Reactivity: Rat FACS, IHC (p), WB Host: Rabbit Polyclonal RB21574 unconjugated
Catalog No. ABIN652612
$412.50
Plus shipping costs $45.00
400 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 10 to 11 Business Days

anti-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) antibody Primary Antibody

CBLB Reactivity: Human IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3015830
$589.88
Plus shipping costs $45.00
100 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 10 to 11 Business Days

anti-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (C-Term) antibody Primary Antibody

CBLB Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855378
$509.08
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 3 to 4 Business Days

anti-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) antibody Primary Antibody

CBLB Reactivity: Human DB, WB Host: Mouse Monoclonal 246C5a unconjugated
Catalog No. ABIN933045
$869.46
Plus shipping costs $45.00
100 μg
local_shipping Shipping to: United States
Delivery in 9 to 11 Business Days

anti-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) antibody Primary Antibody

CBLB Reactivity: Human, Mouse, Rat IF (p), IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN760256
$339.90
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 4 to 6 Business Days

anti-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (full length) antibody Primary Antibody

CBLB Reactivity: Human, Mouse, Rat IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6043252
$417.12
Plus shipping costs $45.00
100 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 18 Business Days

anti-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) antibody Primary Antibody

CBLB Reactivity: Human ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6388803
$367.82
Plus shipping costs $45.00
100 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 13 Business Days

anti-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) antibody Primary Antibody

CBLB Reactivity: Human IF, IHC, ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2135605
$506.61
Plus shipping costs $45.00
50 μL
local_shipping Shipping to: United States
Delivery in 9 to 11 Business Days

anti-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) (AA 862-889), (C-Term) antibody Primary Antibody

CBLB Reactivity: Mouse WB Host: Rabbit Polyclonal RB39998 unconjugated
Catalog No. ABIN1537633
$412.50
Plus shipping costs $45.00
400 μL (More quantities available)
local_shipping Shipping to: United States
Delivery in 10 to 11 Business Days

anti-Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) antibody Primary Antibody

CBLB Reactivity: Human, Mouse, Rat ELISA, IF, IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5696838
$380.00
Plus shipping costs $45.00
100 μg
local_shipping Shipping to: United States
Delivery in 10 to 13 Business Days
  • Type Primary
    • Primary
  • Target Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB)
    • Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB)
    • Histone 3 (H3)
    • Epidermal Growth Factor Receptor (EGFR)
    • Tumor Protein P53 (TP53)
    • Mast/stem Cell Growth Factor Receptor (KIT)
    • Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
    • tau Protein
    • CD4
    • Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2)
    • Tumor Necrosis Factor alpha (TNF alpha)
    • V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1)
    • Interferon gamma (IFNG)
    • Estrogen Receptor 1 (ESR1)
    • Nuclear Factor-kB p65 (NFkBP65)
    • BCL2-Associated Agonist of Cell Death (BAD)
    • V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1)
    • Albumin (ALB)
    • B-Cell CLL/lymphoma 2 (BCL2)
    • Tuberous Sclerosis 2 (TSC2)
    • CD8a Molecule (CD8A)
    • CD19 Molecule (CD19)
    • Platelet/endothelial Cell Adhesion Molecule (PECAM1)
    • Hemagglutinin (HA)
    • CD3 epsilon (CD3E)
    • Jun Proto-Oncogene (JUN)
    • Integrin alpha M (ITGAM)
    • Myc Proto-Oncogene protein (MYC)
    • CD44
    • Histone H4
    • Interleukin 6 (IL6)
    • Interleukin 2 Receptor, alpha (IL2RA)
    • Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1)
    • Vimentin (VIM)
    • CD8
    • C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1)
    • Interleukin 2 (IL2)
    • VEGF Receptor 2 (VEGFR2)
    • Tuberous Sclerosis 1 (TSC1)
    • CD5
    • Insulin Receptor Substrate 1 (IRS1)
    • Amyloid beta (A4) Precursor Protein (APP)
    • Glial Fibrillary Acidic Protein (GFAP)
    • CD14
    • CD34
    • Epithelial Cell Adhesion Molecule (EPCAM)
    • Mucin 1 (MUC1)
    • CD3
    • PTK2 Protein tyrosine Kinase 2 (PTK2)
    • Catenin, beta (CATNB)
    • Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1)
    • Synuclein, alpha (SNCA)
  • Application
    • Western Blotting (WB)
    • ELISA
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Immunofluorescence (Cultured Cells) (IF (cc))
    • Flow Cytometry (FACS)
    • Immunofluorescence (IF)
    • Immunohistochemistry (IHC)
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Dot Blot (DB)
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Immunoprecipitation (IP)
  • Reactivity
    • Human
    • Mouse
    • Rat
    • Cow
    • Guinea Pig
    • Horse
    • Pig
    • Rabbit
  • Images available
  • Preservative free only
  • Host
    • Rabbit
    • Mouse
  • Clonality
    • Polyclonal
    • Monoclonal
  • Clone
    • 246C5a
    • 8C51
    • RB21574
    • RB39998
  • Binding Specificity
    • AA 101-200
    • C-Term
    • AA 862-889
    • AA 103-130
    • AA 861-889
    • Center
    • Internal Region
    • AA 932-982
    • full length
  • Conjugate
    • Un-conjugated
    • Biotin
    • FITC
    • HRP
    • APC
    • Alkaline Phosphatase (AP)
    • PE
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • Alexa Fluor 350
    • Cy3
    • Cy5
    • Cy5.5
    • Cy7
  • Isotype
    • IgG
    • IgG2a
    • Ig Fraction
  • Format
    • Liquid

Cbl Proto-Oncogene B, E3 Ubiquitin Protein Ligase (CBLB) Antigen Profile

Protein Summary

E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. Negatively regulates TCR (T-cell receptor), BCR (B- cell receptor) and FCER1 (high affinity immunoglobulin epsilon receptor) signal transduction pathways. In naive T-cells, inhibits VAV1 activation upon TCR engagement and imposes a requirement for CD28 costimulation for proliferation and IL-2 production. Also acts by promoting PIK3R1/p85 ubiquitination, which impairs its recruitment to the TCR and subsequent activation. In activated T- cells, inhibits PLCG1 activation and calcium mobilization upon restimulation and promotes anergy. In B-cells, acts by ubiquitinating SYK and promoting its proteasomal degradation. Slightly promotes SRC ubiquitination. May be involved in EGFR ubiquitination and internalization. May be functionally coupled with the E2 ubiquitin-protein ligase UB2D3. {ECO:0000269|PubMed:10646608, ECO:0000269|PubMed:10646609, ECO:0000269|PubMed:11070165, ECO:0000269|PubMed:11526404, ECO:0000269|PubMed:12771181, ECO:0000269|PubMed:15308098}.

Gene names and symbols associated with CBLB

  • Cbl proto-oncogene B, E3 ubiquitin protein ligase L homeolog (cblb.L) antibody
  • Casitas B-lineage lymphoma b (Cblb) antibody
  • Cbl proto-oncogene B (Cblb) antibody
  • Cbl proto-oncogene B (CBLB) antibody
  • AI429560 antibody
  • AI851073 antibody
  • Cbl-b antibody
  • cblb antibody
  • rnf56 antibody

Protein level used designations for CBLB

Cas-Br-M (murine) ecotropic retroviral transforming sequence b , Cbl proto-oncogene, E3 ubiquitin protein ligase B , E3 ubiquitin-protein ligase CBL-B-A , SH3-binding protein CBL-B-A , signal transduction protein CBL-B-A , Casitas B-lineage lymphoma proto-oncogene b , E3 ubiquitin-protein ligase CBL-B , RING-type E3 ubiquitin transferase CBL-B , SH3-binding protein CBL-B , Signal transduction protein CBL-B , casitas B-lineage lymphoma proto-oncogene b , signal transduction protein CBL-B , Cas-Br-M (murine) ectropic retroviral transforming sequence b , Casitas B-lineage lymphoma b , Cbl proto-oncogene B, E3 ubiquitin protein ligase , LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase CBL-B , Cas-Br-M ecotropic retroviral transforming sequence b

GENE ID SPECIES
443854 Xenopus laevis
208650 Mus musculus
171136 Rattus norvegicus
100718857 Cavia porcellus
100621690 Sus scrofa
100355469 Oryctolagus cuniculus
525906 Bos taurus
100061819 Equus caballus

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