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Cell Division Cycle Associated 7-Like Proteins (CDCA7L)

Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Additionally we are shipping Cell Division Cycle Associated 7-Like Antibodies (50) and Cell Division Cycle Associated 7-Like Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CDCA7L 217946 Q922M5
CDCA7L 619566 Q4G059
CDCA7L 55536 Q96GN5
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Top Cell Division Cycle Associated 7-Like Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,797.11
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$9,797.11
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,224.83
Details

CDCA7L Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human ,
,

More Proteins for Cell Division Cycle Associated 7-Like (CDCA7L) Interaction Partners

Mouse (Murine) Cell Division Cycle Associated 7-Like (CDCA7L) interaction partners

  1. Mouse JPO2/RAM2 (Cdca7l) interacts with cMyc (show MYC Proteins).

Human Cell Division Cycle Associated 7-Like (CDCA7L) interaction partners

  1. Suppression of CDCA7L limits multiple myeloma proliferation through apoptosis.

  2. We identify the Myc (show MYC Proteins)-interacting protein JPO2 and its partner binding protein LEDGF/p75 (show PSIP1 Proteins) as critical modulators of PI3K (show PIK3CA Proteins)/AKT (show AKT1 Proteins) signaling and metastasis in medulloblastoma

  3. common LEDGF/p75 (show PSIP1 Proteins) interaction interface shared by JPO2, PogZ (show POGZ Proteins), MLL1, IWS1 and HIV IN

  4. The data are consistent with the rs4487645-CDCA7L loci being responsible for the chromosome 7p11.2 association with multiple myeloma risk, probably exerting its effects through an extended pathway involving IRF4 (show IRF4 Proteins) and MYC (show MYC Proteins).

  5. Data indicate that JPO2 and LEDGF/p75 (show PSIP1 Proteins) interact directly and specifically in vivo through the specific interaction domain of JPO2 and the C-terminal domain of LEDGF/p75 (show PSIP1 Proteins).

  6. CDCA7L was able to activate the extracellular signal-regulated kinase 1/2 (show MAPK3 Proteins) (ERK1/2) signaling pathway and regulate the cell cycle, thus promoting HCC (show FAM126A Proteins) progression.

  7. Reduction in R1 repressor protein correlates significantly with an increase (approximately 40%) in monoamine oxidase A (show MAOA Proteins) protein levels within the major depressive disorder groups compared with controls.

  8. monoamine oxidase A (show MAOA Proteins) activation of glucocorticoids and androgens is regulated differently by R1 and Sp1 (show PSG1 Proteins)

  9. demonstrates the functions of MAO A (show MAOA Proteins) and its repressor R1(RAM2/CDCA7L/JPO2) in apoptotic signaling pathways

  10. Over-expression of JPO2 resulted in a modest but reproducible inhibition of HIV-1 replication, consistent with competition between integrase and JPO2 for binding to LEDGF/p75 (show PSIP1 Proteins)

Cell Division Cycle Associated 7-Like (CDCA7L) Protein Profile

Protein Summary

Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Play an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways\; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1 (By similarity).

Gene names and symbols associated with CDCA7L

  • cell division cycle associated 7 like (CDCA7L)
  • cell division cycle associated 7 like L homeolog (cdca7l.L)
  • cell division cycle-associated 7-like protein (LOC100454683)
  • cell division cycle associated 7 like (Cdca7l)
  • BC006933 protein
  • JPO2 protein
  • MGC154777 protein
  • R1 protein
  • RAM2 protein
  • RAPGEF5 protein

Protein level used designations for CDCA7L

cell division cycle associated 7-like , transcription factor RAM2 , cell division cycle-associated 7-like protein-like , cell division cycle-associated 7-like protein , Rap guanine nucleotide exchange factor (GEF) 5

GENE ID SPECIES
100067524 Equus caballus
472306 Pan troglodytes
711948 Macaca mulatta
779344 Xenopus laevis
100348574 Oryctolagus cuniculus
100394869 Callithrix jacchus
100454683 Pongo abelii
100472794 Ailuropoda melanoleuca
100585065 Nomascus leucogenys
217946 Mus musculus
619566 Rattus norvegicus
55536 Homo sapiens
420608 Gallus gallus
482347 Canis lupus familiaris
100518624 Sus scrofa
514631 Bos taurus
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