anti-Charged Multivesicular Body Protein 4C (CHMP4C) Antibodies

CHMP4C belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. Additionally we are shipping CHMP4C Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CHMP4C 66371 Q9D7F7
CHMP4C 92421 Q96CF2
CHMP4C 361916 Q569C1
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Top anti-CHMP4C Antibodies at antibodies-online.com

Showing 10 out of 16 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: Chmp4c Sample Tissue: Mouse Liver lysates Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: CHMP4C Antibody [NBP1-81166] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY407666) Immunohistochemistry-Paraffin: CHMP4C Antibody [NBP1-81166] - Immunohistochemical staining of human small intestine shows strong granular positivity in glandular cells. 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: CHMP4C Antibody [NBP2-15888] - Sample (20 ug of whole cell lysate) A: HeLa B: HeLa cytoplasm, 12% SDS PAGE gel, diluted at 1:1000. Western Blot: CHMP4C Antibody [NBP2-15888] - Sample (50 ug of whole cell lysate) A: Mouse Kidney, 12% SDS PAGE gel, diluted at 1:1000. 0.1 mL Log in to see 8 to 11 Days
$516.98
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 11 to 14 Days
$493.17
Details
Human Mouse Un-conjugated WB Western Blot analysis of CHMP4C expression in transfected 293T cell line by CHMP4C MaxPab polyclonal antibody.Lane 1: CHMP4C transfected lysate(25.63 KDa).Lane 2: Non-transfected lysate. 50 μg Log in to see 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated IHC, WB   0.1 mL Log in to see 2 to 3 Days
$445.50
Details
Human Rabbit FITC ELISA   100 μg Log in to see 11 to 16 Days
$412.19
Details
Human Rabbit Biotin ELISA   100 μg Log in to see 11 to 16 Days
$412.19
Details
Human Rabbit HRP ELISA   100 μg Log in to see 11 to 16 Days
$412.19
Details

Top referenced anti-CHMP4C Antibodies

  1. Human Polyclonal CHMP4C Primary Antibody for IHC, WB - ABIN2718533 : Streck, Carmichael, Buchkovich: Nonenvelopment Role for the ESCRT-III Complex during Human Cytomegalovirus Infection. in Journal of virology 2018 (PubMed)

More Antibodies against CHMP4C Interaction Partners

Human Charged Multivesicular Body Protein 4C (CHMP4C) interaction partners

  1. These results show that Chmp4c regulates the mitotic spindle checkpoint by promoting localization of the RZZ complex to unattached kinetochores.

  2. Data demonstrate the biological importance of the abscission checkpoint and suggest that dysregulation of abscission by CHMP4CT232 may synergize with oncogene-induced mitotic stress to promote genomic instability and tumorigenesis.

  3. Results show that CHMP4C, under the regulation of the chromosomal passenger complex, binds to highly curved membranes and promotes the closure of membrane gaps. Two distinctly localized pools of phosphorylated CHMP4C exist during cytokinesisI but the phosphorylation is not required for its assembly into spiral filaments. Also, the centralspindlin complex associates preferentially with the with unphosphorylated form.

  4. CHMP4C mediates radiation resistance in lung cancer cells.

  5. The ESCRT-III subunit CHMP4B is a key effector in abscission, whereas its paralogue, CHMP4C, is a component in the abscission checkpoint that delays abscission until chromatin is cleared from the intercellular bridge.

  6. AURKB phosphorylates CHMP4C at 3 serines its C-terminal tail.Phosphorylation at these sites appears essential for CHMP4C function because their mutation leads to cytokinesis defects.

  7. Single nucleotide polymorphisms in CHMP4C gene is associated with ovarian cancer.

  8. findings show CHMP4C is involved in abscission timing; this function correlated with its differential spatiotemporal distribution during late stages of cytokinesis; CHMP4C functioned in the Aurora B-dependent abscission checkpoint

  9. The Bro1 domain of ALIX binds specifically to C-terminal residues of the human CHMP4C.

CHMP4C Antigen Profile

Protein Summary

CHMP4C belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006

Gene names and symbols associated with CHMP4C

  • charged multivesicular body protein 4C (Chmp4c) antibody
  • charged multivesicular body protein 4C (CHMP4C) antibody
  • charged multivesicular body protein 4C (chmp4c) antibody
  • charged multivesicular body protein 4C L homeolog (chmp4c.L) antibody
  • 2010012P02Rik antibody
  • 2210015K02Rik antibody
  • 2310010I16Rik antibody
  • chmp4c antibody
  • Shax3 antibody
  • SNF7-3 antibody
  • VPS32C antibody
  • zgc:110173 antibody

Protein level used designations for CHMP4C

Snf7 homologue associated with Alix 3 , charged multivesicular body protein 4c , chromatin modifying protein 4C , chromatin-modifying protein 4c , SNF7 homolog associated with Alix 3 , hSnf7-3 , hVps32-3 , vacuolar protein sorting-associated protein 32-3 , vps32-3 , charged multivesicular body protein 4C , Chromatin-modifying protein 4c

GENE ID SPECIES
66371 Mus musculus
92421 Homo sapiens
361916 Rattus norvegicus
550542 Danio rerio
100723062 Cavia porcellus
507572 Bos taurus
444307 Xenopus laevis
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