Chemokine (C-C Motif) Ligand 22 Proteins (CCL22)

CCL22 is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Additionally we are shipping CCL22 Antibodies (185) and CCL22 Kits (108) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CCL22 6367 O00626
CCL22 20299 O88430
CCL22 117551  
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Top CCL22 Proteins at antibodies-online.com

Showing 10 out of 65 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse Un-conjugated 25 μg Log in to see 10 to 12 Days
$251.53
Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,370.21
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,370.21
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,749.58
Details
Escherichia coli (E. coli) Human Un-conjugated 25 μg Log in to see 10 to 12 Days
$251.53
Details
Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 15 to 18 Days
$640.00
Details
Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 15 to 18 Days
$704.00
Details
Escherichia coli (E. coli) Rat His tag,GST tag 100 μg Log in to see 15 to 18 Days
$707.00
Details
Escherichia coli (E. coli) Cow His tag,GST tag 100 μg Log in to see 15 to 18 Days
$768.00
Details
Escherichia coli (E. coli) Dog His tag,GST tag 100 μg Log in to see 15 to 18 Days
$800.00
Details

CCL22 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, , , ,
Mouse (Murine) , ,
,
Rat (Rattus)

More Proteins for Chemokine (C-C Motif) Ligand 22 (CCL22) Interaction Partners

Human Chemokine (C-C Motif) Ligand 22 (CCL22) interaction partners

  1. This review presents key clinical studies of Multiple sclerosis together with experimental studies in animals that have demonstrated functional roles of CCR4, CCL17, and CCL22 in experimental autoimmune encephalomyelitis pathogenesis. [review]

  2. MDC might serve as a marker of pharmacological therapy response in major depressive disorder

  3. Data suggest that high levels of CCL17 and CCL22 in endometrium in women with endometriosis promote (1) recruitment of Tregs, (2) immunosuppression of Tregs, and (3) angiogenesis in endometrium. (Tregs = regulatory T cells)

  4. blood CCL22 levels were positively associated with IgE sensitization at age 2. A high cord blood CCL22/CXCL10 chemokine ratio was significantly associated with a higher risk of allergic sensitization at age 3.

  5. Tumor-associated macrophages promote prostate cancer migration through activation of the CCL22-CCR4 signaling axis.

  6. Elevations in serum MDC and BLC were independently associated with the significant risk of early stage lung adenocarcinoma, even in non-smokers and in stage IA patients.

  7. These results showed that the higher levels of CXCL10, CCL20 and CCL22 were associated with ischemic heart disease. The serum levels of chemokines may influence by the certain traditional risk factors of IHD and some studied SNPs, but did not influence by treatment and gender of patients.

  8. CCL22 plays an important role in supporting gastric cancer development presumably by increasing the percentage of regulatory T cells in the tumor microenvironments. CCL22 levels in sera have a predictive value for gastric cancer peritoneal metastasis and the early recurrence.

  9. The CCL22-mediated enhancement of antitumor responses is however not due to conversion, but rather to redirection of existing regulatory T cells to the site of cutaneous overexpression.

  10. CCL22 and IL-37 with a co-localization in non-small cell lung cancer A549 cells inhibited the proliferation and epithelial-mesenchymal transition process

  11. Data suggest that Th1 (IFN-gamma-inducible protein-10 IP-10/CXCL10) and Th2 (thymus and activation regulated chemokine TARC/CCL17) and (macrophage derived chemokine MDC/CCL22) cooperatively play a role in the development of ankylosing spondylitis (AS).

  12. increased amounts released by neutrophils from fibromyalgia patients

  13. Our results demonstrate that CCL22 is expressed in human placenta. Decidual expression was only observed in miscarriage conditions and correlates with Treg infiltration.

  14. Distinctive Treg associated CCR4-CCL22 expression profile with altered frequency of Th17/Treg cell in the immunopathogenesis of Pemphigus Vulgaris.

  15. type I IFN blocks the regulatory T cell-attracting chemokine CCL22 and thus helps limit the recruitment of regulatory T cells to tumors

  16. First-episode psychosis patients had higher serum CCL22, which decreased substantially following antipsychotic treatment.

  17. Elevated levels of CCL22 found in the ascites could create a chemokine gradient aiding in Treg cells migration. Increased Tregs percentage in the local microenvironment of ovarian cancer might be an important mechanism of immunosuppression.

  18. Circulating CCL22 levels are related to both glioma risk and survival duration independent of age, histology, grade and IDH mutation status. CCL22 should be considered a marker of immune status with potential prognostic value

  19. CCL22 is a novel mediator of lung inflammation following hemorrhage and resuscitation

  20. CCR4 C1014T and CCL22 C16A genetic variations were neither associated with the risk, nor with the progression of colorectal cancer in Iranian population

CCL22 Protein Profile

Protein Summary

This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology.

Gene names and symbols associated with CCL22

  • C-C motif chemokine ligand 22 (CCL22)
  • chemokine (C-C motif) ligand 22 (Ccl22)
  • C-C motif chemokine ligand 22 (Ccl22)
  • ABCD-1 protein
  • CCL22 protein
  • DC/B-CK protein
  • DCBCK protein
  • Mdc protein
  • Scya22 protein
  • STCP-1 protein

Protein level used designations for CCL22

C-C motif chemokine 22 , CC chemokine STCP-1 , MDC(1-69) , macrophage-derived chemokine , small inducible cytokine A22 , small inducible cytokine subfamily A (Cys-Cys), member 22 , small-inducible cytokine A22 , stimulated T cell chemotactic protein 1 , stimulated T-cell chemotactic protein 1 , CC chemokine ABCD-1 , SMALL INDUCIBLE CYTOKINE A22 PRECURSOR (CC CHEMOKINE ABCD-1) (ACTIVATED B AND DENDRITIC CELL-DERIVED) , activated B and dendritic cell-derived , dendritic cell and B cell derived chemokine , small inducible cytokine subfamily A, member 22 , small inducible cytokine subfamily A22 , small inducible cytokine subfamily A (Cys-Cys) member 22 , chemokine (C-C motif) ligand 22

GENE ID SPECIES
6367 Homo sapiens
20299 Mus musculus
117551 Rattus norvegicus
616996 Bos taurus
736543 Pan troglodytes
100686212 Canis lupus familiaris
100516016 Sus scrofa
100716085 Cavia porcellus
101123141 Ovis aries
103348469 Oryctolagus cuniculus
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