Chemokine (C-C Motif) Ligand 9 Proteins (Ccl9)

Mouse (Murine) Chemokine (C-C Motif) Ligand 9 (Ccl9) interaction partners

1. Results show that MIP-1g promotes tumor cell growth in vitro through the activation of NFkB pathway in colorectal tumor cells.

2. we report that chemokine CCL9 was highly induced in Gr-1 (show GSR Proteins)(+)CD11b (show ITGAM Proteins)(+) immature myeloid cells and in premetastatic lung in tumor-bearing mice

3. Plasmid codelivery of murine CCL19 (show CCL19 Proteins) and CCL28 (show CCL28 Proteins) enhanced Ag-specific systemic and mucosal Ab responses to HIV-1 gp140, augmented balanced Th1 (show HAND1 Proteins)/Th2 responses, and increased lymphocyte subsets in various lymphoid tissues.

4. Taken together the data presented strongly suggest that 4T1 mammary tumor cell invasion in vitro is promoted by D1 mesenchymal stem cell secretions, especially the chemokines CCL5 (show CCL5 Proteins) and CCL9.

5. There is protein-DNA interaction between ETV5 (show ETV5 Proteins) and Ccl9, suggesting that ETV5 (show ETV5 Proteins) might be a direct regulator of Ccl9 expression.

6. Mice lacking RXRalpha (show RXRA Proteins) in myeloid cells exhibit reduced levels of CCL6 (show CCL6 Proteins) and CCL9, impaired recruitment of leukocytes to sites of inflammation, and lower susceptibility to sepsis.

7. Results reveal the potential involvement of CCL9 and CCR1 in macrophage and microglial cells by CpG-ODNs and may help understanding the role of the chemokine/chemokine (show CCL1 Proteins) receptor pairs in macrophage/microglia under physiologic and pathologic conditions.

8. MRP-2 may be an important contributing factor in the development of atherosclerosis

9. CCL9 and its receptor CCR1 are the major chemokine (show CCL1 Proteins) and receptor species expressed by osteoclasts, CCL9 has a role in the regulation of bone resorption

10. An important role for CCL9 is demonstrated in the recruitment of CD11b (show ITGAM Proteins)+ dendritic cells to the dome regions of mouse Peyer's patches.